Explore $100K+ Jobs in Kentucky

Find vetted professional opportunities paying $100,000 or more across Kentucky with Ladders. From Louisville and Lexington to growing communities throughout the state, explore roles for experienced professionals ready to take the next step in their careers. Browse openings across industries and compare opportunities that match your skills, experience, and goals.

Professional Opportunities Across Kentucky

Kentucky’s economy includes established sectors such as healthcare, manufacturing, logistics, finance, and technology, alongside growing businesses and regional employers. Opportunities vary by location and experience, with roles in corporate leadership, operations, sales, engineering, healthcare administration, and other professional fields. Review each listing for location, qualifications, compensation details, and work arrangement.

Find the Right Role for Your Experience

Use Ladders to focus your search on vetted jobs with salaries of at least $100,000. Explore positions by title, employer, location, or industry, and consider opportunities in major employment centers as well as other parts of Kentucky. Tailor your resume to each role and highlight measurable results, relevant expertise, and leadership experience.

Advance Your Career in Kentucky

Whether you are planning a career move within Kentucky or considering relocating to the state, compare openings and employer requirements to identify a strong fit. New listings and hiring needs can change, so check back regularly for current $100K+ professional opportunities.

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1,000+

Jobs in Kentucky

Average Salary in USD

Average Salary: $108,183

Sort By: Relevance

$130K - $160K *

Transform data operations by leading our Snowflake platform migration, ensuring security, reliability, and cost efficiency while collaborating across teams to standardize practices and enhance data ma...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$125K - $157K *

Join our dynamic team to design and enhance a web portal application, improving user experience and functionality. Collaborate with engineers and product managers to deliver impactful solutions that s...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$130K - $150K *

Optimize IT operations by managing systems, enhancing security, and leading projects. Ensure seamless network infrastructure and provide technical support while coordinating with vendors and maintaini...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$130K - $155K *

Shape the future of data and AI solutions by driving product success, collaborating with cross-functional teams to align business goals with innovative platforms and ensuring continuous improvement th...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$124K - $153K *

Transform financial management practices by leading budgeting, forecasting, and resource allocation efforts. Collaborate with teams to enhance decision-making and optimize financial systems, ensuring...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$200K - $275K *

Lead the charge in building and scaling a dynamic partner program, driving revenue through strategic alliances and co-selling. Collaborate cross-functionally to establish processes and integrations, e...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Champion product excellence by owning the vision, backlog, and delivery outcomes. Collaborate with stakeholders and technical teams to ensure solutions align with business goals and regulatory standar...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$160K - $200K *

Lead the charge in enhancing client relationships and driving value realization for managed services. Oversee client success strategies, retention, and growth while collaborating cross-functionally to...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$118K - $196K *

Transform public health analytics by leading AI development and deployment. Guide multidisciplinary teams to create scalable solutions, ensuring compliance and quality while driving innovation and col...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Business Services

$100K - $120K *

Elevate sustainability initiatives by leading client engagements in impact inventory, strategy development, and target tracking. Utilize analytical tools to transform sustainability challenges into ac...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$100K - $120K *

Drive coordination and oversight of utility-scale solar site activities, ensuring compliance with quality standards and project requirements. Foster relationships with contractors and stakeholders to...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$110K - $130K *

Drive customer success by fostering executive relationships and ensuring retention and growth across a defined portfolio. Leverage strategic insights to translate customer outcomes into measurable bus...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$96K - $102K *

Join a dynamic team to develop and implement strategic communications initiatives that translate complex research into engaging content for diverse audiences, enhancing visibility and impact across ed...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$65K - $135K *

Champion your career by joining a dynamic team of Life Insurance Agents. Benefit from comprehensive training and a supportive environment as you engage with clients and drive sales in a rapidly expand...

6 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$100K - $120K *

Advance healthcare solutions by driving sales of innovative diagnostic instruments. Engage with key stakeholders to promote QIAstat-Dx systems, ensuring successful adoption and customer satisfaction t...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$190K - $214K *

Lead HCP personal promotion strategy, developing and optimizing initiatives that engage healthcare professionals. Collaborate cross-functionally to ensure compliance and effectiveness in promotional t...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$180K - $225K *

Lead the charge in transforming AI strategies into impactful solutions for revenue teams, collaborating closely with GTM leaders to drive innovation and measurable outcomes while enhancing engineering...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$160K - $180K *

Elevate healthcare creativity by leading innovative campaigns that transform client brands. Collaborate with teams to deliver impactful experiences across digital channels, leveraging insights and eme...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Join a team that's redefining cloud solutions by architecting and delivering complex Azure engagements. Lead migrations, mentor engineers, and drive innovation while ensuring robust security and gover...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$100K - $112K *

Join a team that's transforming customer engagement through innovative product launches. You'll lead cross-functional collaboration, develop training materials, and ensure readiness for market, all wh...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Join the forefront of quality assurance in government logistics. Lead the development and enhancement of a robust Quality Management System across multiple sites, ensuring compliance and operational e...

RemoteRemote

6 days ago

  •   8 - 10 years exp.  •   Consumer Technology

$76K - $124K *

Engage in foundational sales support, collaborating with Client Account Executives to develop skills in territory strategy, deal mechanics, and enterprise sales, while preparing for a quota-carrying r...

RemoteRemote

6 days ago

  •   Less than 5 years exp.  •   Information Technology

$100K - $120K *

Shape the future of automotive sales by leading a dynamic team, developing strategic initiatives, and engaging directly with clients to enhance their repair processes while achieving ambitious sales t...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$150K - $200K *

Bring your expertise to lead sales strategies and customer development across NCC and VIS product lines, driving profitable growth and enhancing commercial processes while fostering collaboration with...

RemoteRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$79K - $109K *

Transform financial operations by owning monthly close processes, ensuring accurate COGS and accruals. Collaborate with leadership to drive data-driven decisions in a dynamic, growth-stage tech enviro...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Consumer Technology

Frequently Asked Questions (FAQ)

  • Where can I find jobs paying $100,000 or more in Kentucky?question toggle

    Browse Ladders for vetted professional openings in Kentucky with salaries of $100,000 or more. Search by job title, employer, industry, or location to narrow your options.

  • What types of high-paying professional jobs are available in Kentucky?question toggle

    Opportunities may include leadership, healthcare administration, manufacturing, logistics, finance, technology, sales, and engineering roles. Availability and qualifications vary by employer and location.

  • Which Kentucky cities have professional job opportunities?question toggle

    Louisville and Lexington are major employment centers, and professional openings may also be available in other Kentucky communities. Check individual listings for the job location and work arrangement.

  • How can I improve my chances of getting a $100K+ job in Kentucky?question toggle

    Target roles that closely match your experience, tailor your resume to the job requirements, and emphasize measurable achievements, specialized expertise, and leadership impact.

  • Are all jobs listed in Kentucky remote or hybrid?question toggle

    Work arrangements vary by position and employer. Review each listing to see whether the role is onsite, hybrid, or remote.