Explore $100K+ Jobs in Kentucky

Find vetted professional opportunities paying $100,000 or more across Kentucky with Ladders. From Louisville and Lexington to growing communities throughout the state, explore roles for experienced professionals ready to take the next step in their careers. Browse openings across industries and compare opportunities that match your skills, experience, and goals.

Professional Opportunities Across Kentucky

Kentucky’s economy includes established sectors such as healthcare, manufacturing, logistics, finance, and technology, alongside growing businesses and regional employers. Opportunities vary by location and experience, with roles in corporate leadership, operations, sales, engineering, healthcare administration, and other professional fields. Review each listing for location, qualifications, compensation details, and work arrangement.

Find the Right Role for Your Experience

Use Ladders to focus your search on vetted jobs with salaries of at least $100,000. Explore positions by title, employer, location, or industry, and consider opportunities in major employment centers as well as other parts of Kentucky. Tailor your resume to each role and highlight measurable results, relevant expertise, and leadership experience.

Advance Your Career in Kentucky

Whether you are planning a career move within Kentucky or considering relocating to the state, compare openings and employer requirements to identify a strong fit. New listings and hiring needs can change, so check back regularly for current $100K+ professional opportunities.

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1,000+

Jobs in Kentucky

Average Salary in USD

Average Salary: $108,152

Sort By: Relevance

$104K - $123K *

Lead a dynamic team managing Moves, Adds & Changes (MAC) and decommissioning projects across a vast portfolio. Drive operational excellence, customer satisfaction, and team development while ensuring...

Reposted 4 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$160K - $190K *

Optimize software engineering strategies to enhance patient support services. Lead cross-functional teams in developing scalable, secure solutions while driving innovation and best practices in a coll...

4 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$124K - $158K *

Engage in transforming health care by delivering exceptional patient care, overseeing pharmacy operations, and leading a dedicated team. Your role is vital in ensuring safe dispensing, enhancing patie...

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$106K - $176K *

Join a team that's transforming healthcare finance by leading patient financial services operations. Drive revenue cycle improvements, manage billing processes, and enhance compliance while fostering...

United StatesRemote

4 days ago

  •   11 - 15 years exp.  •   Business Services

$110K - $125K *

Engage with a dynamic team to oversee copy responsibilities, crafting compelling content across various mediums. Collaborate creatively to drive engagement for diverse audiences, including healthcare...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$88K - $105K *

Join a dynamic team as you drive innovation in technical design, ensuring quality and scalability in product development. Collaborate with cross-functional teams to enhance manufacturing operations an...

4 days ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$110K - $130K *

Empower your career by joining a dynamic team as a Field Support Engineer, where you'll tackle complex technical challenges in mission-critical environments, leveraging your expertise in Red Hat OpenS...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Elevate your career by contributing to critical security initiatives, leveraging your expertise in incident response, cryptographic modernization, and technical policy formulation to enhance enterpris...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Information Technology

$103K - $155K *

Join a dedicated team focused on innovating multi-factor authentication strategies to combat digital fraud. Collaborate across functions to design frameworks that enhance security, improve customer ac...

Reposted 4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$175K *

Engage with high-net-worth clients, converting prospects to loyal partners. Leverage provided leads and support to educate about wealth management solutions while developing your sales expertise in a...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$83K - $104K *

Join a team that's driving strategic marketing initiatives and influencing success. Collaborate with leaders to develop compelling narratives and innovative strategies that elevate project pursuits an...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$87K - $157K *

Lead the charge in executing the Medicare Compliance Advisory program, ensuring adherence to CMS regulations. Collaborate with stakeholders to provide regulatory guidance, assess compliance risks, and...

RemoteRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $110K *

Drive valuable insights by enhancing Anaplan models and dashboards, collaborating with teams to implement solutions and improve functionality, while supporting users throughout the development lifecyc...

United StatesRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$120K - $160K *

Join a team to lead commissioning projects, providing technical expertise and project management for critical facilities. Collaborate across teams, mentor others, and ensure successful testing and val...

United StatesRemote

Reposted 4 days ago

  •   11 - 15 years exp.  •   Technical Services

$385K - $400K *

Transform regional sales performance by leading a high-impact team, driving strategic growth, and utilizing best practices to meet ambitious quotas within a dynamic environment. Foster relationships a...

RemoteRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Information Technology

$212K - $287K *

Transform the Hematology landscape by leading a high-performing sales team, driving strategic initiatives, and ensuring compliance while exceeding sales objectives in the Great Plains region...

RemoteRemote

4 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$184K - $356K *

Drive technical engagement with telecom accounts, connecting customer workloads to NVIDIA's ecosystem. Serve as a trusted advisor, co-design scalable architectures, and lead technical enablement to en...

RemoteRemote

4 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$145K - $170K *

Join us to drive strategic sales initiatives, leveraging a robust resource model and tech stack to achieve performance goals and maximize customer value in a dynamic, collaborative environment...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$85K - $192K *

Engineer innovative mainframe solutions to enhance critical business operations. Collaborate with cross-functional teams to optimize performance, ensure reliability, and align IT strategies with Mater...

4 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$132K - $250K *

Shape your career by driving enhancements in yield, quality, and efficiency. Collaborate with teams to leverage AI, build data models, and implement actionable solutions that advance plant performance...

Reposted 4 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$80K - $90K *

Transform the claims landscape by managing commercial property claims, collaborating with diverse teams, and enhancing your expertise in global and excess lines. Join a dynamic environment focused on...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$100K - $120K *

Engage with small and medium-sized businesses as a Direct Sales Leader, leveraging your extensive sales experience to train and mentor new team members while managing your own client relationships and...

Reposted 4 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$80K - $95K *

Empower the CDL program by leading training initiatives, ensuring compliance, and optimizing fleet management. Collaborate with regional leaders to enhance operational efficiency and drive revenue gro...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$124K - $158K *

Lead pharmacy operations by ensuring safe dispensing, patient care, and team performance. Collaborate with management to enhance patient experiences and maintain compliance while fostering a supportiv...

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$135K - $160K *

Lead the charge in developing and executing CMC strategies for antibody-based radiopharmaceuticals, ensuring alignment with Stage-Gate requirements while managing cross-functional teams and external p...

RemoteRemote

4 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • Where can I find jobs paying $100,000 or more in Kentucky?question toggle

    Browse Ladders for vetted professional openings in Kentucky with salaries of $100,000 or more. Search by job title, employer, industry, or location to narrow your options.

  • What types of high-paying professional jobs are available in Kentucky?question toggle

    Opportunities may include leadership, healthcare administration, manufacturing, logistics, finance, technology, sales, and engineering roles. Availability and qualifications vary by employer and location.

  • Which Kentucky cities have professional job opportunities?question toggle

    Louisville and Lexington are major employment centers, and professional openings may also be available in other Kentucky communities. Check individual listings for the job location and work arrangement.

  • How can I improve my chances of getting a $100K+ job in Kentucky?question toggle

    Target roles that closely match your experience, tailor your resume to the job requirements, and emphasize measurable achievements, specialized expertise, and leadership impact.

  • Are all jobs listed in Kentucky remote or hybrid?question toggle

    Work arrangements vary by position and employer. Review each listing to see whether the role is onsite, hybrid, or remote.