Explore $100K+ Jobs in Kentucky

Find vetted professional opportunities paying $100,000 or more across Kentucky with Ladders. From Louisville and Lexington to growing communities throughout the state, explore roles for experienced professionals ready to take the next step in their careers. Browse openings across industries and compare opportunities that match your skills, experience, and goals.

Professional Opportunities Across Kentucky

Kentucky’s economy includes established sectors such as healthcare, manufacturing, logistics, finance, and technology, alongside growing businesses and regional employers. Opportunities vary by location and experience, with roles in corporate leadership, operations, sales, engineering, healthcare administration, and other professional fields. Review each listing for location, qualifications, compensation details, and work arrangement.

Find the Right Role for Your Experience

Use Ladders to focus your search on vetted jobs with salaries of at least $100,000. Explore positions by title, employer, location, or industry, and consider opportunities in major employment centers as well as other parts of Kentucky. Tailor your resume to each role and highlight measurable results, relevant expertise, and leadership experience.

Advance Your Career in Kentucky

Whether you are planning a career move within Kentucky or considering relocating to the state, compare openings and employer requirements to identify a strong fit. New listings and hiring needs can change, so check back regularly for current $100K+ professional opportunities.

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1,000+

Jobs in Kentucky

Average Salary in USD

Average Salary: $108,152

Sort By: Relevance

$123K - $186K *

Drive strategic initiatives by conducting data analysis and market research, collaborating with cross-functional teams, and crafting executive presentations to enhance operational effectiveness in a d...

RemoteRemote

4 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$166K - $244K *

Join a dynamic team to lead the Employer PMO, driving strategic program delivery and cross-functional alignment while enhancing operational efficiency and leveraging modern tools for impactful outcome...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $190K *

The Consulting Manager for Workday Benefits will lead teams in delivering complex implementations and system optimizations for Workday Benefits. This role requires expertise in benefits administration...

RemoteRemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$95K - $115K *

Lead global clinical laboratory projects by ensuring operational excellence, client satisfaction, and effective cross-functional collaboration while mentoring junior project managers to elevate team p...

Kentucky, USRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$114K - $187K *

Optimize clinical data management processes by leading teams and ensuring compliance with standards. Collaborate with stakeholders to enhance data quality and streamline operations across multiple com...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Drive growth by developing strategic partnerships in the travel industry. Leverage your expertise to identify opportunities, negotiate agreements, and support travel advisors and agencies in maximizin...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $95K *

Engage with mission-driven organizations to drive growth in housing solutions. Own the full sales lifecycle, from prospecting to closing, while expanding your portfolio and collaborating across teams...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$175K - $200K *

Champion customer success by driving enterprise account value and adoption. Collaborate with stakeholders to ensure measurable outcomes, orchestrate resources, and uncover growth opportunities while f...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$88K - $105K *

Drive your career with a dynamic role focused on designing and implementing innovative logistics solutions. Collaborate with cross-functional teams to enhance client operations and deliver value-drive...

RemoteRemote

4 days ago

  •   5 - 7 years exp.  •   Transportation

$210K *

Unlock potential by joining a dynamic telehealth team, providing compassionate, patient-centered care across Kentucky. Enjoy flexible scheduling while managing diverse clinical cases through secure vi...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$210K *

Champion high-quality virtual care by managing diverse clinical cases through telehealth. Collaborate with a dedicated team to deliver patient-centered treatment plans while enjoying a flexible schedu...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$82K - $182K *

Analyze healthcare costs and quality outcomes to drive value-based care strategies, collaborating with clinical and financial teams. Lead data-driven insights and financial modeling to enhance operati...

RemoteRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$135K - $176K *

Join us to lead a pharmacy team dedicated to exceptional patient care, promoting best practices, and fostering a culture of excellence while navigating the evolving healthcare landscape and ensuring c...

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$145K - $175K *

Pioneer the future of data center construction by leading innovative manufacturing strategies, ensuring seamless integration of offsite components, and driving efficiency through advanced technologies...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$75K - $100K *

Engage with clients and drive sales as you build a rewarding career in life insurance. Enjoy comprehensive training, a supportive environment, and unlimited income potential while helping clients secu...

4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$90K - $110K *

Inspire and lead a dynamic sales team by mastering our sales system, closing deals, and training new agents. Drive success through effective coaching while achieving personal sales goals in a fast-pac...

4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$109K - $186K *

Champion business growth across European defense markets by developing strategies, engaging stakeholders, and managing sales cycles. Build long-term relationships to position solutions as the preferre...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$125K - $150K *

Drive new business growth by leveraging industry relationships and expertise in AdTech. Own the sales cycle, navigate complex deals, and collaborate with internal teams to deliver technology-driven ad...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $120K *

Help us shape the future of construction financing by leveraging your experience in loan origination. Join our dynamic team and gain direct access to a nationwide market, empowering clients with tailo...

United StatesRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$121K - $170K *

Lead the charge in delivering exceptional customer experiences through strategic oversight and collaboration across teams, ensuring operational excellence and strong client outcomes in a dynamic envir...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$102K - $177K *

Transform the sales training landscape by designing and executing innovative educational programs for Trauma & Extremities, enhancing team competency and driving strategic growth in alignment with glo...

United StatesRemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$84K - $140K *

Unlock potential by driving procurement strategies for advanced manufacturing. Collaborate with teams to manage supplier relationships, oversee bidding processes, and ensure compliance with purchasing...

4 days ago

  •   5 - 7 years exp.  •   Business Services

$170K - $210K *

Lead the design and implementation of cross-platform solutions in AWS GovCloud, focusing on Informatica architecture, security, and CI/CD practices. Collaborate with multidisciplinary teams to ensure...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Business Services

$110K - $130K *

Lead operational excellence and strategic initiatives to enhance growth, efficiency, and compliance across all facilities. Foster a culture of continuous improvement while overseeing program developme...

Reposted 4 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$104K - $166K *

Join a team that's dedicated to enhancing cybersecurity operations. As a Senior SOC Analyst, you'll monitor threats, analyze network traffic, and lead incident response efforts while mentoring junior...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

Frequently Asked Questions (FAQ)

  • Where can I find jobs paying $100,000 or more in Kentucky?question toggle

    Browse Ladders for vetted professional openings in Kentucky with salaries of $100,000 or more. Search by job title, employer, industry, or location to narrow your options.

  • What types of high-paying professional jobs are available in Kentucky?question toggle

    Opportunities may include leadership, healthcare administration, manufacturing, logistics, finance, technology, sales, and engineering roles. Availability and qualifications vary by employer and location.

  • Which Kentucky cities have professional job opportunities?question toggle

    Louisville and Lexington are major employment centers, and professional openings may also be available in other Kentucky communities. Check individual listings for the job location and work arrangement.

  • How can I improve my chances of getting a $100K+ job in Kentucky?question toggle

    Target roles that closely match your experience, tailor your resume to the job requirements, and emphasize measurable achievements, specialized expertise, and leadership impact.

  • Are all jobs listed in Kentucky remote or hybrid?question toggle

    Work arrangements vary by position and employer. Review each listing to see whether the role is onsite, hybrid, or remote.