Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,016

Sort By: Relevance

$100K *

Lead the charge in transforming patient care by driving sales of innovative visual electrophysiology solutions. Build relationships with eye care professionals, deliver impactful demonstrations, and e...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Explore a pivotal role in financial management, ensuring accuracy in reporting, compliance with GAAP, and supporting audits. Drive process improvements while mentoring junior staff and collaborating a...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$135K - $160K *

Shape the future of global employee services by leading a scalable organization that enhances support, streamlines processes, and leverages AI for seamless service delivery across diverse regions and...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Information Technology

$103K - $181K *

Shape the future of secure software by developing full-stack applications that support critical government missions. Collaborate with diverse teams to deliver reliable, scalable solutions in dynamic e...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Real Estate & Construction

$203K - $285K *

Advance security solutions by engaging with enterprise customers, providing expert guidance, and driving strategic initiatives. Collaborate across teams to enhance security practices and ensure compli...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Information Technology

$175K - $210K *

Drive revenue growth by leading a high-performing sales team focused on acquiring new clients in managed services. Collaborate with marketing to develop effective prospecting campaigns and establish p...

United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Information Technology

$68K - $106K *

Join a team that's driving growth by acquiring new logos and expanding market presence. You'll navigate complex sales cycles, build relationships from scratch, and directly impact company growth while...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$149K - $175K *

Accelerate growth by driving enterprise sales in the public sector, focusing on large SLED accounts. Leverage your expertise to navigate complex procurement processes and build strategic relationships...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$103K - $181K *

Lead the charge in wastewater treatment engineering, driving innovative solutions for municipal and industrial projects. Collaborate with multidisciplinary teams to ensure compliance, efficiency, and...

United StatesRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Real Estate & Construction

$250K - $280K *

Champion strategic growth by leading a high-performing sales team focused on K-12 core curriculum and supplemental products. Drive revenue, build talent, and foster partnerships with education leaders...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$93K - $158K *

Unlock potential by providing expert technical guidance to customers, ensuring successful adoption of GitLab's solutions. Collaborate with cross-functional teams to deliver tailored enablement and sup...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$103K - $181K *

Shape the future of training by leading curriculum development and event execution. Collaborate with instructors and management to ensure high-quality training programs that meet project goals and enh...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Real Estate & Construction

$145K - $175K *

Transform your career by leading cross-functional teams to drive drug development strategies. Collaborate with key stakeholders to ensure successful execution of integrated plans, manage risks, and de...

United StatesRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Champion the delivery of multi-team software programs, ensuring alignment across offshore development pods while driving AI-native methodologies and continuous improvement for optimal performance and...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$100K - $110K *

Join a team that's transforming data into actionable insights through Power BI. In this hands-on role, you'll develop dashboards and reports, ensuring data quality and collaboration across stakeholder...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$90K - $120K *

Accelerate progress at Attendance Plus by owning product positioning and go-to-market strategies. Collaborate with cross-functional teams to enhance student attendance solutions, driving adoption and...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Optimize coding quality and compliance through independent audits, validation, and collaboration with healthcare teams. Drive improvements in accuracy, consistency, and regulatory adherence to enhance...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

Drive impactful change by providing therapeutic support and guidance to clients, enabling their journey toward recovery through individualized therapy and collaborative treatment strategies. Play a pi...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Healthcare

$103K - $134K *

Champion customer success by managing complex accounts, driving growth, and ensuring seamless communication. Collaborate with internal teams to enhance operational efficiency and deliver value, while...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Healthcare

$110K - $148K *

Transform global congress planning by leading cross-functional teams, managing timelines, and ensuring quality execution. Drive strategic alignment and operational excellence to deliver impactful cong...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $100K *

Join a team that's dedicated to providing homeowners peace of mind through expert pest control solutions. Drive sales by conducting inspections, building trust, and showcasing the value of our service...

Yesterday

  •   Less than 5 years exp.  •   Staffing

$90K *

Optimize clinical workflows by configuring and supporting Epic EHR systems. Collaborate with healthcare teams to enhance system performance, ensure compliance, and provide training, while driving cont...

Yesterday

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$90K *

Champion the optimization of clinical workflows by configuring and supporting Epic EHR systems. Collaborate with healthcare teams to enhance system performance, ensure compliance, and provide training...

Yesterday

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$90K *

Contribute to optimizing clinical workflows by configuring and supporting Epic EHR applications. Collaborate with healthcare teams to enhance system performance, ensure compliance, and provide trainin...

Yesterday

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$155K - $175K *

Unlock potential by leading treasury operations, managing liquidity, and optimizing investment strategies. Drive risk management and compliance while fostering banking relationships in a dynamic finte...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.