Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.
Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.
Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.
Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.
Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.
Average Salary: $110,075
SAP Data Migration Senior Manager - CMT/SemiConductors
$132K - $302K *
Elevate enterprise data migration strategies for S/4HANA transformations. Lead complex projects, mentor teams, and engage with stakeholders to ensure data quality and successful execution across diver...
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$100K - $120K *
Shape the future of cloud applications by developing scalable modules and enhancing legacy systems. Collaborate with teams to ensure high-quality code and optimize performance within an Agile framewor...
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$118K - $140K *
Join a dynamic team to oversee the implementation and support of enterprise solutions, ensuring quality control and project management excellence while collaborating with clients on technical deployme...
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Director of Engineering, Advertiser Experience
$150K - $180K *
Empower engineering teams to innovate advertiser tools, driving technical strategy and delivery while enhancing user experience across self-service and managed workflows in a dynamic ad tech environme...
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Director, Field Medical Affairs (East)
$170K - $200K *
Lead and innovate within the Field Medical Affairs team, driving strategic alignment and operational excellence. Foster collaboration and scientific integrity while mentoring a high-performing team to...
Today
Director of Operational Finance
$160K - $170K *
Elevate your career by partnering with divisional leadership to drive financial strategy, enhance operational efficiency, and ensure accurate financial reporting within a dynamic SaaS environment. Mak...
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Senior Product Marketing Manager, CPQ
$140K - $160K *
Empower sales teams by owning the go-to-market strategy for CPQ. Collaborate with product and sales leadership to define messaging, drive adoption, and enhance revenue operations through innovative ma...
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Sr. Manager, Revenue Management Services (Medicaid Operations)
$150K - $195K *
Join a team that's redefining Medicaid operations. Lead a high-performing team, drive compliance, and enhance rebate management processes while ensuring client satisfaction and operational excellence...
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Pharmacist | 40 hours per week | Inpatient Pharmacy
$131K *
Champion safe and effective pharmaceutical care by supervising pharmacy staff, developing clinical programs, and providing expert medication therapy consultations to enhance patient outcomes and suppo...
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Audio AI Research Scientist - Audio Source Separation
$165K - $227K *
Unlock your potential as you develop cutting-edge AI algorithms for real-time audio processing. Collaborate with experts to enhance audio experiences through innovative source separation techniques an...
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$80K - $100K *
Join a dynamic team to build lasting client relationships, oversee accounts, and deliver tailored pest management solutions. Leverage industry expertise and innovative tools to drive sales and ensure...
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Quantitative Model Validator, NLP and Gen AI/ Agentic AI
$100K - $196K *
Unlock potential by validating advanced NLP and AI models, ensuring compliance and performance. Collaborate across teams in a dynamic environment, leveraging your quantitative expertise to drive impac...
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$90K - $110K *
Empower clinical excellence by leading a team of Care Guide RNs while managing a caseload of active members. Drive performance, coaching, and quality metrics in a hybrid role that blends leadership wi...
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Principal Technologist - 90335753 - Remote
$113K - $146K *
Empower innovation by leading the design and implementation of advanced technology solutions. Collaborate with teams to enhance operational efficiency, automate processes, and improve user experiences...
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Vice President, Decision Science
$160K - $220K *
Join us to lead and expand our Analytics practice, driving data insights and marketing strategies while managing a talented team in a dynamic and evolving digital landscape...
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$70K - $100K *
Champion new business growth by identifying and converting prospects into clients. Own the full sales cycle, leveraging data insights and consultative selling to drive urgency and deliver tailored sol...
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$91K - $129K *
Champion your career by managing and enhancing Salesforce environments. Collaborate with cross-functional teams to streamline workflows, support users, and drive impactful projects that scale business...
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Maintenance Technical Leader - Ingot
$80K - $95K *
Empower excellence in maintenance leadership, driving performance and safety while managing skilled teams in a dynamic manufacturing environment. Collaborate across departments to achieve key objectiv...
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Maintenance Technical Leader - Ingot
$80K - $95K *
Transform the Ingot Department by leading maintenance teams, ensuring safety and productivity, and driving reliability and performance through effective management and strategic initiatives within a d...
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Regional Sales Manager - Commercial & Industrial Water Treatment
$100K - $120K *
Unlock potential by driving commercial and industrial water treatment sales. Manage customer accounts, develop strategies, and actively participate in trade shows, ensuring robust client relationships...
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$135K - $203K *
Transform the Unity platform for Android ecosystems by optimizing performance and enabling seamless deployment across devices. Collaborate with teams to enhance software capabilities and drive innovat...
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Lead Transmission Line Engineer
$92K - $166K *
Empower a dynamic team by leading high voltage transmission line projects, ensuring quality design and execution while fostering collaboration and innovation in a fast-paced environment. Drive client...
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Manager of Quality Improvement
$80K - $95K *
Advance quality improvement initiatives by managing diverse health services, ensuring compliance with contract deliverables, and leading a dedicated team to achieve operational excellence and strategi...
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Channel Manager | Enterprise Accounts
$110K - $130K *
Empower your career by driving strategic partnerships and revenue growth. Collaborate with leadership to implement alliance strategies, enhance partner relationships, and promote ADP's value propositi...
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AI Marketing Strategist (PST based)
$120K - $150K *
Empower ecommerce brands to leverage AI marketing tools effectively, guiding users to understand and implement solutions that enhance their growth strategies while fostering confidence in AI capabilit...
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What kinds of $100,000+ jobs are available in Iowa?
Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.
Which Iowa cities have professional jobs listed?
Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.
Are all jobs on this page guaranteed to pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.
How can I find the right high-paying job in Iowa?
Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.