Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,016

Sort By: Relevance

$110K - $130K *

Empower teams by translating complex data into actionable insights, guiding strategic financial modeling, and enhancing decision-making processes for portfolio companies through collaborative relation...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$119K - $186K *

Lead transformative process improvements by leveraging customer insights to enhance operational excellence across Health Systems & Government Services, ensuring scalable, customer-centered execution a...

RemoteRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$180K - $225K *

Lead the charge in shaping the future of consumer products for anglers. Drive growth by setting a visionary roadmap, developing a high-performing team, and delivering exceptional user experiences that...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Enterprise Technology

$207K - $244K *

Shape the future of payment methods by owning the strategy and roadmap for customer bank accounts, cards, and digital wallets, ensuring seamless integration and optimal performance across platforms...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$72K - $90K *

Join a supportive team to provide telehealth psychotherapy for older adults. Enjoy flexible scheduling, a full caseload, and minimal paperwork while making a meaningful impact in patients' lives. Your...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Elevate your career by leading a dynamic BDR team, driving pipeline generation, and optimizing sales processes. Collaborate with marketing and sales to enhance engagement strategies while fostering ta...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$95K - $110K *

Transform construction management through collaboration with franchisees and cross-functional teams. Oversee site feasibility, planning, and execution of new shop projects to ensure timely, cost-effec...

RemoteRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Food & Beverages

$100K - $130K *

Join our team to conduct ISO/IATF 16949 audits across North America, ensuring compliance and quality. Engage with clients at all management levels, providing detailed reports and guidance while mainta...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Business Services

$110K - $145K *

Elevate medical communications by developing high-quality, strategic content across therapeutic areas. Collaborate with teams and clients to ensure accuracy and adherence to guidelines while supervisi...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K *

Partner with us to lead recruitment initiatives and workforce planning, driving talent acquisition strategies across skilled nursing and assisted living sectors. Collaborate with leaders to build stro...

Yesterday

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$215K - $250K *

Build your career with a pioneering role to shape grantmaking, partner programs, and organizational independence. Lead initiatives, engage stakeholders, and measure success while establishing a founda...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$95K - $105K *

Unlock potential by conducting advanced quantitative analyses in behavioral health research. Collaborate with senior investigators on diverse projects, manage data, and produce insightful reports to d...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$100K - $200K *

Transform your career by leading key client relationships, understanding business goals, and driving innovative manufacturing solutions to market. Leverage your expertise to boost sales and collaborat...

United StatesRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$63K - $98K *

Lead the charge in ensuring seamless onboarding for new customers, coordinating efforts across teams to deliver a professional transition from sales to support, while fostering strong relationships an...

RemoteRemote

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$75K - $125K *

Empower growth by driving strategic account management and sales initiatives. Collaborate with diverse teams to deliver innovative manufacturing solutions, ensuring client success and exceeding revenu...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$164K - $241K *

Lead a global TPRM program, enhancing vendor security risk management through AI-driven workflows and assessments. Manage a team, ensure compliance, and drive risk decisions while collaborating with c...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$86K - $138K *

Optimize financial analysis and reporting by conducting in-depth research, preparing forecasts, and collaborating across departments to enhance business outcomes and drive strategic decision-making...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$100K - $110K *

Join us to drive cross-functional GTM initiatives, enhance operational efficiency, and support executive decision-making. You'll collaborate with teams to align strategies and improve processes, ensur...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$115K - $160K *

Transform the quality oversight program for unsecured lending by executing risk-based testing, documenting findings, and collaborating with cross-functional teams to enhance compliance and operational...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$128K - $191K *

Join a team that's driving growth in the CBRNe Safety & Security sector. You'll identify new business opportunities, develop strategies, and manage the sales cycle while collaborating with cross-funct...

RemoteRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$159K - $211K *

Drive enterprise technology portfolio strategy and governance, ensuring effective delivery management and performance visibility. Collaborate with leadership to translate strategy into actionable init...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$104K *

Champion legal excellence by representing the County in complex criminal, juvenile, and civil cases. Collaborate with officials, mentor junior attorneys, and provide strategic legal counsel while ensu...

Yesterday

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$135K - $160K *

Elevate your career by leading strategic initiatives that drive provider growth. Collaborate with C-suite leaders to design scalable operations and align cross-functional teams, while mentoring a dedi...

United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Healthcare

$92K - $115K *

Unlock your potential by providing holistic patient care across diverse settings. Collaborate with a dedicated team to enhance health outcomes for underserved populations while navigating evolving hea...

Yesterday

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$145K - $160K *

Drive the future of Workforce AI by leading business development initiatives, engaging with executives, and translating complex technology into impactful solutions that enhance enterprise productivity...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.