Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,016

Sort By: Relevance

$150K - $180K *

Drive transformational growth by managing critical customer relationships and partnerships. Leverage AI insights to shape enterprise strategies, influence executive decisions, and mentor sales profess...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Technical Services

$85K - $95K *

Develop and deliver engaging training programs to enhance user adoption and operational excellence. Collaborate with diverse teams to create effective learning solutions, ensuring content aligns with...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$185K - $275K *

Transform the future of IT programs by leading a dynamic team in planning, budgeting, and compliance. Drive performance and innovation while ensuring alignment with organizational goals in a fully rem...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Information Technology

$95K - $115K *

Lead the charge in managing engineering and manufacturing projects, collaborating across teams to ensure timely execution, budget adherence, and high-quality outcomes that drive business growth and in...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$116K - $164K *

Engineer comprehensive land development projects for EV and AV charging stations. Oversee design, permitting, and construction phases while managing budgets and client communications. Collaborate with...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Real Estate & Construction

$95K *

Advance your career by auditing outpatient and specialty claims, ensuring coding accuracy and compliance. Leverage your clinical and coding expertise to enhance audit processes and contribute to quali...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Healthcare

$180K - $220K *

Lead the charge in transforming healthcare revenue cycles by optimizing financial operations, ensuring compliance, and enhancing patient experiences. Drive strategic initiatives and foster collaborati...

RemoteRemote

Yesterday

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$175K - $210K *

Transform the accounting landscape by leading a multi-disciplinary team, enhancing operational efficiency, and driving innovation through AI and automation while ensuring compliance and integrity in f...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Information Technology

$80K - $95K *

Drive impactful decision-making and support for EHRM initiatives, enhancing operational efficiency and stakeholder engagement through strategic analysis, project management, and effective communicatio...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Shape the future of healthcare IT by managing complex integration programs, driving Lean-Agile adoption, and ensuring successful delivery of enterprise reporting and analytics initiatives across multi...

United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Healthcare

$70K - $120K *

Drive data analytics to enhance audit and compliance processes, leveraging technical skills to improve efficiency and risk management across various assurance activities. Collaborate with cross-functi...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$162K - $195K *

Join a team that's dedicated to launching innovative cardiac therapies. Drive sales performance, build strategic relationships, and serve as a key resource in your territory, focusing on patient needs...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$162K - $195K *

Drive sales performance by launching a novel cardiac myosin inhibitor, building strategic relationships with healthcare providers, and coordinating a local integrated field team to meet patient needs...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$75K - $123K *

Join a team that's dedicated to enhancing Payment Integrity Audit programs by collaborating with stakeholders, managing inventory, and driving process improvements in a fast-paced environment focused...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Business Services

$85K - $110K *

Elevate quality assurance in clinical DRG audits by mentoring auditors, ensuring accuracy, and recommending process improvements. Collaborate with peers to enhance performance and uphold compliance st...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Business Services

$93K - $163K *

Drive effective marketing strategies for cybersecurity offerings, collaborating with cross-functional teams to enhance product management and deliver impactful go-to-market initiatives, while ensuring...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Information Technology

$73K - $101K *

Unlock potential by leading installation, maintenance, and repair of low voltage power distribution systems. Collaborate with teams to ensure safety and efficiency while delivering exceptional service...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$90K - $110K *

Transform enterprise modernization by leading user-centered design and business analysis initiatives. Collaborate with stakeholders to optimize workflows, enhance user experiences, and drive strategic...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$175K - $237K *

Empower your leadership skills by overseeing county operations, managing budgets, and driving strategic initiatives. Collaborate with diverse teams to enhance service delivery and ensure effective gov...

Yesterday

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Lead the charge in enhancing complex Federal applications by designing, developing, and maintaining full-stack solutions using Java and Angular. Collaborate in an Agile environment to deliver secure...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$100K - $120K *

Elevate your career by driving sales in the employer benefits space. Shape growth, manage relationships, and collaborate across teams to deliver impactful solutions for SMB clients in the Rocky Mounta...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Hospitality & Recreation

$85K - $90K *

Unlock potential by leading a dynamic Customer Success team to enhance client satisfaction, drive product adoption, and identify upselling opportunities, ensuring customers achieve their business goal...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Enterprise Technology

$95K - $105K *

Champion dealership sales performance by collaborating with management to enhance digital strategies, optimize processes, and drive effective communication, ensuring maximum impact on sales outcomes a...

Yesterday

  •   Less than 5 years exp.  •   Enterprise Technology

$125K *

Empower your sales career by driving growth in the SaaS/Security sector. Build relationships with key decision-makers, exceed quotas, and collaborate across teams to deliver exceptional value and solu...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$112K - $140K *

Transform the future of software development by architecting and enhancing back-end solutions across diverse applications, mentoring engineers, and driving Agile processes to deliver high-quality soft...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.