Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,075

Sort By: Relevance

$205K - $256K *

Transform your career by leading Apollo's data strategy, ensuring the highest quality B2B data for GTM success. Drive product vision, collaborate cross-functionally, and enhance customer experiences t...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$404K - $500K+*

Transform the Federal Civilian landscape by leading sales teams to drive adoption of cybersecurity and data solutions. Cultivate executive relationships, establish GTM strategies, and achieve multi-mi...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$235K - $291K *

Champion strategic leadership across diverse digital and marketing initiatives, guiding cross-disciplinary teams and fostering client relationships to drive impactful solutions and business growth in...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Technical Services

$150K - $180K *

Drive enterprise sales strategy for innovative agentic products, building relationships with key decision-makers. Collaborate with product and engineering teams to translate customer needs into compel...

RemoteRemote

2 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$94K - $293K *

Join a team that's redefining data architecture by leading scalable, governed solutions. Leverage your expertise to guide engineering best practices and ensure high-quality data management across ente...

2 weeks ago

  •   8 - 10 years exp.  •   Business Services

$110K - $145K *

Optimize compensation strategies by providing expert advisory support, leading complex analyses, and enhancing program effectiveness. Collaborate with leaders to ensure alignment with business needs a...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$110K - $145K *

Shape the future of military aviation by developing and testing Flight Management System software. Collaborate with engineering teams to deliver reliable avionics solutions, leveraging your expertise...

2 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$88K - $154K *

Engineer innovative Electronic Security Systems solutions for diverse clients, guiding projects from concept to construction. Collaborate with teams to ensure compliance with specifications and delive...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$110K - $130K *

Drive impactful employment law solutions as a Virtual Office Counsel, managing administrative charges and litigation while collaborating with a skilled legal team in a flexible, remote environment foc...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Staffing

$80K - $90K *

Transform your marketing career by driving product strategies and campaigns. Collaborate with cross-functional teams to create compelling messaging and targeted programs that enhance customer engageme...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$152K - $190K *

Engage with mid-sized customers to drive IoT solutions, managing complex sales cycles and building relationships with key stakeholders. Your efforts will directly impact industries that keep our world...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$85K - $100K *

Drive financial excellence by owning month-end close, reconciliations, and management reporting. Collaborate with leadership to enhance processes and ERP systems, ensuring accuracy and compliance as t...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Food & Beverages

$124K - $169K *

Optimize cross-portfolio analytics to enhance Gross-to-Net performance, identify anomalies, and drive process improvements. Collaborate with diverse teams to deliver actionable insights and scalable r...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$83K *

Engage with group leaders to enhance fundraising efforts, ensuring compliance and support. Manage administrative functions, track spending, and foster collaboration across departments while promoting...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$95K - $115K *

Transform manufacturing processes by designing and implementing advanced PLC/HMI control systems for food and beverage plants, ensuring optimal performance and efficiency through innovative automation...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Technical Services

$100K - $300K *

Unlock potential by driving enterprise growth in non-commercial foodservice technology. Own the full sales lifecycle, engage stakeholders, and deliver tailored solutions that enhance operational effic...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$95K - $115K *

Unlock your potential by developing innovative control systems for diverse industries. Collaborate with clients to solve complex manufacturing challenges through automation and controls, ensuring effi...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Technical Services

$177K - $221K *

Champion regulatory excellence by leading cross-functional teams, ensuring compliance, and driving successful oncology drug development through strategic planning and expert guidance...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$76K - $103K *

Drive the management and operation of county parks and wildlife areas, overseeing staff, maintenance, and public engagement to enhance facilities and ensure safety for all visitors...

2 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$80K - $100K *

Unlock potential by leading a dynamic team of developers to deliver high-quality software solutions, collaborating with stakeholders, and driving strategic project initiatives while fostering a cultur...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$109K - $145K *

Contribute to the development of a cloud storage solution, designing and delivering features for a medical imaging platform. Collaborate within an Agile team, taking ownership of the development lifec...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $90K *

Join a dynamic team to drive product marketing and ABM strategies, enhancing customer engagement and market presence through compelling messaging and targeted campaigns that foster growth and awarenes...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$192K - $235K *

Lead analytical development and quality control for sterile parenteral products, ensuring regulatory compliance and successful product launches. Collaborate cross-functionally to establish strategies...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$85K - $90K *

Help us lead a dynamic accounting team, overseeing financial operations and ensuring compliance across multiple projects while driving process improvements and fostering collaboration in a remote envi...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$135K - $160K *

Lead the charge in scaling our Customer Success Management team, driving product adoption and retention across diverse customer segments. Collaborate cross-functionally to create impactful processes a...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Legal & Accounting

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.