Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,075

Sort By: Relevance

$125K - $150K *

Champion the enhancement of financial reporting processes and efficiencies, ensuring accurate visibility into organizational performance. Collaborate with leadership on strategic projects to drive ope...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$125K - $150K *

Join a team that's redefining identity management across diverse platforms. You'll architect secure authentication and authorization systems, ensuring seamless access for users and organizations while...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$232K - $348K *

Lead the charge in oncology pharmacology, managing scientific teams to drive drug discovery from early stages through regulatory approval while ensuring alignment across cross-functional teams...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Empower your career by joining a dynamic team as an Epic Prelude Analyst, driving enhancements in patient access and revenue cycle workflows through collaboration and innovative solutions...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $115K *

Join us to support advanced Warehouse Robotics in the field, delivering exceptional service and solutions to our North American customers. Leverage your technical expertise and customer empathy to dri...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$152K - $210K *

Transform workforce data into actionable insights by leading People programs, systems, and analytics. Drive strategic initiatives, enhance operational efficiency, and foster a culture of continuous im...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$82K - $97K *

Join a dynamic team to enhance client interactions and drive sales support. Leverage your logistics expertise to identify growth opportunities and streamline operations, ensuring exceptional service a...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Transportation

$106K - $141K *

Join a team that's building an AI-ready data foundation for marketing and GTM. You'll design, govern, and analyze data models, ensuring reliable insights for strategic decision-making across the organ...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$160K - $190K *

Champion project control excellence by developing strategies, collaborating with teams, and optimizing performance to ensure successful project delivery within timelines and budgets. Lead initiatives...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$210K - $250K *

Shape the future of healthcare by leading a dynamic clinic team, enhancing patient care, and driving operational excellence in a collaborative environment. Enjoy a rewarding career with competitive co...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Unlock potential by leading innovative demand generation strategies that drive pipeline growth and market engagement. Collaborate across departments to optimize campaigns and mentor teams, ensuring al...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$146K - $196K *

Transform genomic insights into clinical applications by designing automated solutions and integrating AI/ML approaches. Collaborate with cross-functional teams to enhance variant curation and ensure...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$185K - $312K *

Engineer the future of home shopping by developing a foundational AI model that integrates market dynamics, consumer behavior, and economic factors to enhance user experience and decision-making in re...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$110K - $130K *

Shape the future of secure software development by integrating security practices into engineering workflows, building automation tools, and conducting penetration tests to identify vulnerabilities an...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $105K *

Transform creative visions into tangible assets by managing the entire production lifecycle. Oversee timelines, quality control, and vendor relationships to ensure projects are delivered on-brand, on...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Media

$72K - $116K *

Engage in financial analysis and reporting, developing forecasts and insights. Collaborate across departments to enhance business outcomes and present findings to management, driving strategic decisio...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$170K - $200K *

Unlock potential by leading product strategy for organic discovery and AI visibility across a vast platform. Drive client success through innovative solutions, collaborating with engineering and desig...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$89K - $115K *

Shape innovative software solutions by designing, developing, and maintaining robust applications. Collaborate with cross-functional teams to enhance user experience and optimize application performan...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Lead the charge in designing scalable, cloud-based SaaS solutions for Higher Education. Collaborate with cross-functional teams to translate institutional needs into actionable solutions, ensuring ali...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$109K - $197K *

Lead the design and implementation of MuleSoft integration solutions, focusing on API development and cloud deployments. Collaborate with teams to translate business needs into technical specification...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$95K - $115K *

Lead the charge in developing robust Java/Spring backend services, enhancing data processing and reliability for financial institutions. Collaborate with a skilled team to drive technical improvements...

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $215K *

Lead the charge in developing a cutting-edge compliance program for consumer financial products. You'll oversee a team, drive strategy, and ensure adherence to regulations in a fast-paced, innovative...

RemoteRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$83K *

Elevate community health by delivering compassionate nursing care, ensuring adherence to care plans, and fostering a collaborative environment among team members to enhance residents' well-being and q...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$125K - $150K *

Advance the future of financial engineering by building a robust platform for pricing, billing, and revenue management in an AI-driven environment. Collaborate cross-functionally to automate processes...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Inspire patient recruitment strategies by leading a dynamic team, collaborating with senior management, and leveraging innovative tools to enhance enrollment across clinical trials while ensuring dive...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.