Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,075

Sort By: Relevance

$115K - $275K *

Manage the delivery of GPU clusters for AI workloads by coordinating teams across engineering, networking, and operations. Develop strategies, manage risks, and ensure timely, quality launches to scal...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Drive strategic initiatives and operational excellence across a global portfolio, partnering with leadership to enhance business performance and deliver measurable outcomes in oncology and rare diseas...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Transform client engagement by leading a dynamic conflicts managed services practice. Drive service quality, team development, and innovative solutions while shaping a scalable model for modernizing c...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$135K - $185K *

Transform enterprise architecture by defining our technology strategy, guiding scalable solutions, and leading modernization initiatives that align with business goals. Thrive in a role that fosters i...

RemoteRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Transportation

$98K - $120K *

Shape the future of manufacturing by driving safety, quality, and cost improvements. Collaborate with innovative teams to implement continuous improvement projects and support new product introduction...

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$120K - $171K *

Join a dynamic team to develop and present complex utility cases, focusing on regulatory issues and litigation. Collaborate with experts to shape policy and strategy while committing to public service...

2 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$160K - $200K *

Take ownership of transformative initiatives in higher education, serving as a trusted expert and strategic advisor. Drive top-of-funnel growth, enhance institutional partnerships, and elevate academi...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$144K - $200K *

Lead the charge in developing a high-performing sales team focused on mid-sized public safety agencies. Drive recruitment, coaching, and team success while leveraging AI tools to enhance sales strateg...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Consumer Technology

$100K - $120K *

Elevate demo quality by owning and customizing demo environments, ensuring they are reliable and tailored for the go-to-market team. Collaborate with cross-functional teams to enhance demo readiness a...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$100K - $150K *

Join a team that's dedicated to enhancing healthcare revenue cycles by conducting assessments, managing operations, and building client relationships. Leverage your expertise to drive improvements and...

2 weeks ago

  •   5 - 7 years exp.  •   Legal & Accounting

$106K - $130K *

Join a dynamic team as you lead distributor strategies and drive sales growth across South Texas, Louisiana, and Mississippi. Collaborate cross-functionally to optimize performance and ensure successf...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Food & Beverages

$135K - $160K *

Shape the future of geospatial science by leading the design and development of innovative data processing pipelines and APIs, while mentoring engineers and setting technical direction in a dynamic, m...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$78K - $119K *

Unlock potential by managing complex workers' compensation claims, driving investigations, and shaping strategies. Build relationships, ensure compliance, and mentor others while making a direct impac...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$86K - $138K *

Champion financial analysis and reporting by conducting in-depth research, preparing forecasts, and collaborating across departments to enhance decision-making and drive business success...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Empower revenue operations by architecting and optimizing scalable GTM systems. Collaborate with cross-functional teams to translate complex business needs into automated solutions, ensuring seamless...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$100K - $125K *

Empower your career by driving growth in the Fiberglass Pools market. In this dynamic sales role, you'll identify new business opportunities, expand market presence, and achieve sales targets while co...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$175K - $190K *

Shape the future of ERP and Finance transformation by guiding clients through strategic assessments, technology alignment, and implementation execution, leveraging your Oracle Finance expertise to dri...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $95K *

Drive your career forward by overseeing essential accounting activities, ensuring compliance with GAAP and government contracting regulations. Leverage your expertise in financial reporting, general l...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$85K - $120K *

Unlock your potential by leading operational excellence in training programs. Drive performance, streamline processes, and enhance client experiences in a dynamic, remote environment. Collaborate acro...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$150K - $200K *

Drive impactful marketing strategies in the Healthcare sector, enhancing positioning and messaging. Collaborate cross-functionally to accelerate growth and establish thought leadership, ensuring relev...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$190K - $267K *

Transform safety enforcement through data science by developing models and systems that detect and mitigate abuse. Collaborate across teams to translate policies into actionable insights, ensuring eff...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Media

$110K - $130K *

Drive your career with a pivotal role in systems engineering, bridging design and compliance teams to select cutting-edge technologies for military-grade products, ensuring high performance and reliab...

2 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Lead the selection of advanced electronics technologies, bridging design and compliance engineering to ensure high-performance product development for military applications...

2 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$120K - $170K *

Transform enterprise software systems by leading design and development efforts, ensuring scalable, secure applications that meet federal mission needs while mentoring engineers and driving best pract...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$95K - $115K *

Develop innovative software solutions using Microsoft technologies, focusing on both front-end and back-end systems. Collaborate with teams to ensure high-quality, secure, and scalable applications in...

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.