Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,016

Sort By: Relevance

$80K - $95K *

Engineer innovative civil designs for utility-scale solar and battery projects. Collaborate with multidisciplinary teams to create site layouts, grading, and drainage plans, ensuring compliance and ef...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Energy & Utilities

$210K *

Explore a rewarding telehealth role delivering patient-centered care across Iowa. Manage diverse clinical cases with flexibility in scheduling, while collaborating with a dedicated team to enhance vir...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$210K *

Pioneer innovative telehealth solutions by delivering high-quality, patient-centered care across Iowa. Manage diverse clinical cases remotely, ensuring flexibility and work-life balance while collabor...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$126K - $234K *

Unlock potential by designing and delivering innovative training solutions for customer-facing teams, enhancing product knowledge and engagement skills across diverse therapeutic areas and roles...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$115K - $140K *

Join us to drive revenue growth by engaging senior finance leaders, executing full-cycle sales, and delivering tailored software solutions that address financial challenges and enhance operational eff...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$120K - $140K *

Unlock your potential as a Forward Deployed Engineer, bridging AI solutions with enterprise needs. Collaborate closely with clients to architect and implement robust systems, ensuring real-world appli...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $150K *

Transform the mobile landscape by architecting a scalable React Native application. Lead engineering standards, mentor developers, and integrate enterprise systems to enhance user experience across iO...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Transportation

$110K - $130K *

Grow your career with a dynamic design role focused on transforming complex supply chain systems into intuitive user experiences. Collaborate with teams to enhance operational efficiency and drive imp...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Transportation

$110K - $130K *

Join the charge in shaping CoreView's Federal market presence by leading strategic field marketing initiatives, enhancing brand awareness, and driving lead generation campaigns to establish a robust p...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $115K *

Take ownership of strategic account management to drive growth and enhance educational outcomes. Collaborate with key stakeholders, leverage data insights, and implement targeted strategies to maximiz...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$180K - $200K *

Elevate healthcare technology by owning mobile and web apps that enhance clinician workflows. Drive product direction, prioritize initiatives, and ensure patient safety while leveraging AI to improve...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$162K - $258K *

Drive the design and implementation of cutting-edge GenAI solutions, leading the development of LLM capabilities and ML pipelines to enhance insurance workflows and deliver impactful outcomes for cust...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$100K - $120K *

Join our team to provide specialized pharmacy services in adult clinics, collaborating with healthcare professionals to enhance patient care through medication management, education, and support for c...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$112K - $197K *

Lead the charge in enhancing patient care and pharmacy operations while managing a dedicated team. Drive community outreach initiatives and ensure compliance with regulations to improve health outcome...

2 weeks ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$150K - $180K *

Transform the infrastructure landscape by leading Site Reliability Engineering and platform architecture for global expansion, ensuring reliability, cost efficiency, and compliance across multiple ser...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $375K *

Champion the evolution of Code Archaeology by owning methodologies, assets, and technical leadership. Drive large-scale modernization efforts while shaping market perspectives and ensuring quality in...

2 weeks ago

  •   11 - 15 years exp.  •   Business Services

$80K - $95K *

Champion the future of hospice care by leading diverse teams across multiple locations. Drive operational excellence, enhance patient care, and foster relationships with staff and stakeholders while e...

West Des Moines, IARemote

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Join us in leading hospice care across Iowa and Omaha! As a Travel Hospice Program Director, you'll drive operational excellence, enhance patient care, and build high-performing teams in diverse envir...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Champion operational excellence and quality care as you lead diverse hospice teams across multiple locations, ensuring high standards and fostering relationships with staff, patients, and community pa...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Join us to manage and coordinate operational activities across multiple cardiology sites, ensuring high-quality services while collaborating with physicians and staff. Drive strategic planning and com...

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Advance your career by managing operations across multiple cardiology sites. Collaborate with physicians to ensure high-quality services, oversee staff performance, and maintain compliance with regula...

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Manage and coordinate operational activities across multiple locations, ensuring high-quality, cost-effective services. Collaborate with physicians, oversee staff performance, and maintain compliance...

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Engage your leadership skills to manage and coordinate operations across multiple cardiology sites. Collaborate with physicians to ensure high-quality services while overseeing staff performance and c...

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$80K - $134K *

Elevate compliance standards by conducting detailed FedRAMP assessments, analyzing technical artifacts, and collaborating with clients to ensure security controls are effectively implemented and docum...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$106K - $114K *

Lead the charge in driving strategic partnerships, managing budgets, and optimizing performance. Collaborate cross-functionally to enhance partner success and deliver impactful training programs, ensu...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.