Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,016

Sort By: Relevance

$136K - $182K *

Redefine commercial pricing strategies by leveraging advanced actuarial analysis, supporting portfolio-level assessments, and mentoring junior colleagues within a dynamic, remote team of professionals...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$200K - $225K *

Lead the charge in optimizing property tax strategies across North America, ensuring compliance and minimizing liabilities. Collaborate cross-functionally to drive impactful decisions and enhance tax...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Join a team that's shaping the future of aftermarket solutions by driving growth through strategic customer engagement and innovative lifecycle management. Collaborate cross-functionally to enhance pr...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$73K - $100K *

Elevate workforce planning by transforming data into impactful insights. Partner with leaders to build strategic forecasting tools and measure performance metrics, contributing to operational efficien...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $110K *

Champion growth by developing strategic partnerships in international airfreight. Drive profitable expansion through client engagement, leveraging expertise in logistics solutions to enhance market pr...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Transportation

$79K - $83K *

Help us advance hearing solutions by providing clinical and sales support across North and Central Virginia. Join a dedicated team and develop expertise in cochlear implants while building strong cust...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Elevate your career with a dynamic team focused on innovative accounting solutions. Lead financial processes, ensure compliance, and drive efficiency in a fast-paced environment while collaborating cr...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Elevate your career by managing a dynamic team, ensuring exceptional service delivery, and fostering employee development while driving customer satisfaction across diverse sectors...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$108K - $250K *

Champion the promotion of innovative oncology solutions, enhancing patient care through strategic partnerships with healthcare providers and key opinion leaders, while driving brand growth and deliver...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$131K - $200K *

Join a team that's shaping the future of data platforms by developing scalable solutions for analytics and AI workloads. Collaborate on impactful projects using cutting-edge tools to enhance data reli...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Shape the future of brand strategy by crafting distinct messaging and positioning for a diverse portfolio of university partners. Collaborate with cross-functional teams to optimize campaigns and enha...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$90K - $150K *

Lead the charge in transforming healthcare systems through data-driven insights and collaborative engagement. Drive performance improvement by managing analytics projects, delivering client solutions...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Advance your career by driving impactful Paid Social strategies across platforms like Meta and TikTok. Collaborate with cross-functional teams to optimize campaigns, leverage data insights, and enhanc...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Media

$105K - $120K *

Join a dynamic team to lead and enhance information security programs, ensuring compliance and risk management across diverse industries. Collaborate with executives to develop strategies that protect...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$160K - $185K *

Lead the charge in developing compelling proposals for government contracts, managing the entire proposal process from strategy to submission. Collaborate with cross-functional teams to ensure complia...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Technical Services

$110K - $130K *

Take ownership of comprehensive cyber risk assessments across the enterprise, articulating risks in business terms to ensure informed decision-making by leadership and helping to strengthen the organi...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Technical Services

$78K - $113K *

Unlock potential by leading complex revenue cycle projects, providing analytical support, and collaborating across departments to enhance billing processes and resolve financial issues in a fast-paced...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K *

Champion the clinical operations team, ensuring project success through resource management, process efficiencies, and compliance. Drive training, metrics development, and mentorship to enhance team c...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Join our new Data Engineering team to lead business intelligence initiatives, build trusted data models in Snowflake, and deliver impactful reports in Power BI. Collaborate with stakeholders to enhanc...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$100K - $120K *

Champion endpoint strategy and governance, leading a specialized team to deliver secure, scalable services across diverse devices. Collaborate with IT and business leaders to drive automation, operati...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$85K - $128K *

Unlock potential by driving cloud security sales initiatives, collaborating with teams, establishing partnerships with key personas, and engaging customers to integrate innovative security solutions i...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$77K - $118K *

Transform network operations by designing and implementing automation solutions that enhance reliability and efficiency across multi-vendor infrastructures, utilizing advanced technologies like Python...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$77K - $118K *

Drive the evolution of scalable, secure platforms by architecting solutions that enhance network intelligence and application delivery, collaborating with cross-functional teams to optimize performanc...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$174K - $234K *

Champion the development and governance of global transfer pricing strategies, ensuring alignment with business operations and compliance across jurisdictions while leading cross-functional collaborat...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$204K - $274K *

Champion the U.S. Biologics Regulatory CMC team by providing strategic leadership, ensuring timely regulatory submissions, and fostering collaboration among global stakeholders to drive innovative bio...

United StatesRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.