Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,016

Sort By: Relevance

$80K - $105K *

Join a specialized team to evaluate biological research, ensuring safety against misuse. Utilize your expertise to distinguish legitimate science from potential threats, contributing to AI safety and...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$135K - $160K *

Join a dynamic team to architect and implement a next-gen Design System, ensuring consistent, accessible experiences across products. Collaborate with cross-functional teams to drive technical alignme...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Food & Beverages

$201K - $251K *

Elevate access strategies and marketing initiatives for oncology products, focusing on non-clinical value propositions. Collaborate cross-functionally to ensure successful product launches and effecti...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$255K - $424K *

Lead the development and execution of Immunology access services strategy, ensuring seamless patient and provider experiences. Collaborate cross-functionally to enhance reimbursement initiatives and d...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Join a dynamic team as you drive continuous improvement initiatives, enhancing operational efficiency and fostering a culture of excellence across the organization. Collaborate with cross-functional t...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$142K - $160K *

Champion privacy compliance in the Neurology therapeutic area, providing expert guidance on data protection, contract negotiation, and training. Collaborate with cross-functional teams to ensure adher...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$70K - $150K *

Drive growth in oral surgery practices by building relationships, pursuing new sales opportunities, and achieving targets. Leverage your sales expertise to deliver exceptional customer service and sup...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$130K - $155K *

Advance your career by leading engineering teams in the critical restoration and operational readiness of a nuclear facility, ensuring compliance and technical excellence while driving Iowa's clean en...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Energy & Utilities

$110K - $130K *

Join us to minimize access barriers for patients and providers, executing market access plans across multiple states. Collaborate with healthcare professionals to resolve reimbursement issues and enha...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $350K *

Join a team that's building scalable, high-performance backend systems using TypeScript. Collaborate across functions to optimize trading solutions and tackle complex challenges in the blockchain spac...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$120K - $145K *

Empower your career by leading the design and implementation of Oracle Field Service solutions for utility organizations. Collaborate with stakeholders to enhance operational performance and customer...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Staffing

$110K - $130K *

Unlock potential by overseeing a portfolio of enterprise accounts, fostering strategic partnerships, and driving user engagement to achieve measurable outcomes. Collaborate with internal teams to deli...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Legal & Accounting

$227K - $335K *

Empower growth through strategic marketing leadership, leveraging data insights to drive customer engagement and revenue. Build and mentor a high-performing team to transform analytics into actionable...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Transportation

$155K - $259K *

Transform healthcare performance by leading integrated optimization programs that enhance clinical, operational, and financial outcomes for hospitals and health systems. Drive measurable results throu...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$110K - $130K *

Shape the future of product design by transforming concepts into high-fidelity experiences. Collaborate with cross-functional teams to enhance user interactions through innovative prototyping and AI-a...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$150K - $180K *

Join a team that's driving growth in the biopharmaceutical sector by developing strategic business relationships, prospecting new clients, and leading sales initiatives to achieve organizational objec...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$135K - $145K *

Partner with us to elevate healthcare communications by crafting compelling copy for HCP campaigns. Lead creative initiatives, collaborate with cross-functional teams, and ensure brand consistency acr...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$163K - $203K *

Shape the future of defense infrastructure by leading technical engagements and ensuring successful project execution. Collaborate with stakeholders to deliver innovative solutions that meet mission-c...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Enterprise Technology

$115K - $120K *

Elevate your career by providing impactful telehealth counseling to clients. Utilize your expertise to support individuals facing emotional and relational challenges while maintaining professional sta...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$84K - $124K *

Join us to lead the acquisition and management of right of way agreements for fiber optic projects across North America, collaborating with stakeholders to ensure compliance and successful negotiation...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$93K - $191K *

Drive strategic federal contract administration, overseeing complex engagements and advising leadership on compliance, negotiation, and performance to enhance revenue retention and operational success...

1 week ago

  •   8 - 10 years exp.  •   Business Services

$100K - $120K *

Lead procurement initiatives by providing expert acquisition support to enhance operational efficiency and compliance within federal programs, ensuring successful project execution and stakeholder col...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Technical Services

$102K - $190K *

Pioneer the future of endpoint security by leading a dynamic engineering team, ensuring operational excellence, and driving innovative capabilities to protect enterprise assets while aligning with bus...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $160K *

Join a team that's redefining data solutions by leading technical sales efforts, collaborating with Account Managers, and driving customer success through innovative data architecture and tailored dem...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$126K - $164K *

Pioneer innovative solar designs for utility-scale projects, leading teams to optimize high-level concepts into actionable plans. Engage with clients and ensure quality standards while contributing to...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.