Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.
Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.
Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.
Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.
Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.
Average Salary: $110,016
Senior Product Manager, Secret Detection and Vulnerability Research
$138K - $165K *
Drive GitLab's Secret Detection and Vulnerability Research efforts to shape security product outcomes. Own the detection lifecycle, ensure content quality, and leverage AI to enhance operational effic...
Reposted 1 week ago
$150K - $180K *
Drive innovation in power systems architecture by collaborating with hyperscalers and partners to develop cutting-edge connector and cable solutions. Lead technical programs, influence strategic objec...
1 week ago
Physician (Diagnostic Radiologist)
$210K - $250K *
Empower patient care through expert image interpretation and guidance in diagnostic radiology. Collaborate on quality assurance, oversee technical standards, and educate staff while ensuring optimal p...
1 week ago
Sales Enablement Program Manager
$110K - $150K *
Lead the charge in enhancing sales performance through targeted enablement initiatives. You'll work closely with diverse sales teams to coach, train, and build effective tools, ensuring impactful and...
Reposted 1 week ago
$90K - $110K *
Shape the future of patient care by leading nursing operations across multiple departments, fostering clinical excellence, and enhancing staff development while ensuring quality and safety in a collab...
1 week ago
Territory Sales Representative, Implants MIS
$82K - $150K *
Accelerate growth by driving new customer acquisition and expanding market share in the dental implant sector. Leverage a hunter mentality to convert competitive accounts and position value-oriented s...
Reposted 1 week ago
$150K - $220K *
Oversee a specialized team to ensure AI safety in biological research, addressing dual-use risks and providing expert guidance on complex cases while mentoring junior specialists and advising clients...
1 week ago
Supply Chain Plant Manager (m/f/d)
$100K - $120K *
Drive supply chain excellence by managing the lifecycle of components, ensuring efficient logistics and material flow, and collaborating with global stakeholders to optimize operations for maximum eff...
Reposted 1 week ago
$117K - $150K *
Champion your actuarial expertise to drive financial reporting and reserve setting for annuities. Collaborate on high-impact projects, adapt to evolving needs, and enhance reporting models in a dynami...
1 week ago
$110K - $130K *
Lead strategic initiatives by managing complex projects from inception to launch. Collaborate across teams to implement new markets and contracts, ensuring compliance and operational readiness in a dy...
1 week ago
VP Business Development - Auto - Heavy Equipment Solutions
$150K - $180K *
Advance business growth by building strategic relationships and identifying client needs. Drive sales initiatives and ensure seamless implementation of client programs while meeting profit margins and...
1 week ago
$117K - $176K *
Accelerate progress at the forefront of electromechanical design, leading product development for circuit breakers. Collaborate across teams to ensure compliance, quality, and innovation while mentori...
1 week ago
$135K - $160K *
Optimize backend systems for a financial platform, integrating AI features and ensuring reliability across multiple regions. Collaborate with global teams to enhance product capabilities and maintain...
1 week ago
Production Manager - Des Moines, IA
$95K - $115K *
Oversee the manufacturing environment to achieve production, quality, and cost goals. Lead teams, manage resources, and drive continuous improvement initiatives while ensuring compliance with safety a...
Reposted 1 week ago
Senior Forward Deployed UX Designer (Asheville, NC or Nashville, TN)
$140K - $223K *
Unlock potential by leading human-centered design efforts in clinical settings, translating user insights into AI-enabled solutions that enhance patient care and clinician efficiency within a collabor...
1 week ago
$110K - $150K *
Engage as a key Contract Manager, overseeing procurement agreements and providing strategic guidance across teams. Collaborate on complex projects, ensuring compliance and effective negotiation while...
1 week ago
$100K - $160K *
Lead critical evaluations of biological risks, mentor junior specialists, and ensure high-quality labeling for AI safety classifiers in a dynamic life-sciences environment focused on biodefense and bi...
1 week ago
$160K - $229K *
Transform client experiences by leading SAP CX solutions, ensuring seamless integration and delivery from discovery to go-live while collaborating with cross-functional teams to drive business success...
1 week ago
$133K - $173K *
Unlock potential by leading the commissioning of hyperscale data centers. Manage project lifecycles, coordinate teams, and ensure compliance with client requirements while fostering strong stakeholder...
1 week ago
Account Manager, Client Development & Renewals (Chicago / Midwest)
$123K - $135K *
Engage with existing customer accounts to drive renewal retention and expansion revenue. Collaborate with cross-functional teams to identify growth opportunities and ensure customer satisfaction while...
1 week ago
Chief Editorial and Insights Officer
$200K - $210K *
Champion innovative content strategies to transform editorial operations, enhance audience engagement, and establish a trusted resource for leaders in government and education. Drive organizational ch...
1 week ago
Business Development Executive
$90K - $95K *
Advance your career by driving new business growth through proactive outreach, building strong relationships, and consistently exceeding sales targets in a dynamic, remote environment focused on B2B s...
1 week ago
$80K - $95K *
Manage client engagements end-to-end while mentoring associates and driving team success. Leverage technical expertise to resolve complex tax issues and enhance client service through collaboration an...
1 week ago
VP, Law Firm Professional Services
$250K - $300K *
Shape the future of AI-powered implementations by leading a dynamic team, redefining best practices, and building a robust partner ecosystem to enhance client success and drive growth in a fast-paced...
1 week ago
$131K - $243K *
Advance your career by driving enterprise sales and building strong client relationships. Leverage your expertise in SaaS solutions to identify opportunities, negotiate contracts, and deliver tailored...
1 week ago
What kinds of $100,000+ jobs are available in Iowa?
Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.
Which Iowa cities have professional jobs listed?
Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.
Are all jobs on this page guaranteed to pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.
How can I find the right high-paying job in Iowa?
Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.