Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down
1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,016

Sort By: Relevance

$87K - $209K *

Join a dynamic team to design and implement backend services, enhancing developer tooling and integration frameworks. Drive improvements in performance and resilience while collaborating with cross-fu...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$120K - $145K *

Shape the future of cybersecurity by providing expert guidance and support to clients. Collaborate with cross-functional teams to enhance customer experience and drive adoption of solutions, ensuring...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$155K - $185K *

Transform the technology landscape by leading cross-functional teams to enhance Medicaid Enterprise Systems, driving system architecture improvements and mentoring engineers towards high-quality, secu...

United StatesRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Enterprise Technology

$145K - $160K *

Lead the charge in transforming member support by defining strategy, enhancing team performance, and integrating AI solutions. Drive operational excellence while fostering a culture of empathy and acc...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Tackle the challenges of building scalable backend services in a cloud environment. Collaborate with cross-functional teams to enhance the Temporal Cloud experience, focusing on reliability, performan...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$95K - $159K *

Empower the future of medical technology by ensuring the highest quality in embedded systems. Collaborate with cross-functional teams to drive compliance and innovation in software development for lif...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $155K *

Elevate product initiatives within the casino vertical by driving discovery, stakeholder engagement, and roadmap management. Collaborate with cross-functional teams to enhance player experience and en...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$90K - $125K *

Join a team that's dedicated to building robust software solutions. Collaborate with cross-functional teams to design, develop, and maintain high-quality applications while ensuring reliability and pe...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Transportation

$100K - $120K *

Engage with new business opportunities to drive growth and market share in the South-Central U.S. Collaborate with teams to launch solutions, manage customer relationships, and achieve sales targets w...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$105K - $115K *

Empower a dynamic sales team to drive revenue growth through strategic partnerships and innovative territory planning. Shape the future of business development by fostering relationships and deliverin...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$95K - $100K *

Join a dynamic team as a Senior Strategist, where you'll lead data-driven strategies, mentor talent, and drive innovative solutions in healthcare advertising. Collaborate with creative teams to enhanc...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$210K - $230K *

Lead the charge in developing enterprise pricing strategies that optimize profitability and drive growth across diverse service sectors, ensuring alignment with market conditions and client needs whil...

RemoteRemote

1 week ago

  •   11 - 15 years exp.  •   Real Estate & Construction

$110K - $130K *

Elevate your career by developing and optimizing machine learning models, collaborating with cross-functional teams to drive data-driven solutions and enhance predictive analytics in a dynamic, Agile...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $199K *

Develop and maintain scalable data pipelines, leveraging Snowflake and cloud tools to enhance data quality and accessibility. Mentor a growing team while driving best practices in data engineering and...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$120K - $145K *

Lead the charge in web growth design, optimizing top-of-funnel experiences to enhance customer engagement and conversion. Collaborate with cross-functional teams to create compelling, high-quality web...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$110K - $130K *

Unlock potential by leading the full sales cycle, building executive relationships, and driving business transformation across industries. Collaborate with teams to innovate sales processes and ensure...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$315K - $370K *

Join a team that's redefining offensive security by leading engineering efforts to transform research into scalable, customer-facing products. Drive strategy, execution, and innovation across multiple...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$208K - $250K *

Unlock your potential by joining a thriving multi-specialty clinic, collaborating with a diverse team to deliver quality patient care and utilizing a robust referral network in a collegial, supportive...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$208K - $250K *

Inspire excellence in patient care at a leading multi-specialty clinic, where you'll collaborate with a dynamic team of healthcare professionals to enhance services and drive better outcomes in a supp...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$208K - $250K *

Join a team that's dedicated to exceptional patient care and outcomes. Work alongside a large, collaborative group of physicians in a supportive environment that prioritizes your growth and offers com...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$208K - $250K *

Join a team that's redefining internal medicine, collaborating with a skilled group of professionals to deliver high-quality patient care across multiple locations in a supportive, family-friendly atm...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$208K - $250K *

Contribute to a leading multi-specialty clinic by delivering high-quality care as an Internal Medicine Physician. Collaborate with a diverse team to provide excellent patient outcomes in a supportive...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$210K - $250K *

Join a team that's redefining internal medicine with a collaborative, patient-centric approach. Engage with diverse cases, foster professional growth, and enjoy a family-friendly environment in a lead...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$90K - $110K *

Unlock potential by leading compliance initiatives and advising leadership on regulatory strategies. This role ensures adherence to laws, mentors staff, and collaborates with stakeholders to mitigate...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$89K - $171K *

Transform your career by connecting with healthcare professionals and driving product utilization. In this dynamic role, you'll lead sales efforts, build relationships, and contribute to patient care...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.