Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,016

Sort By: Relevance

$90K - $110K *

Manage a comprehensive food and beverage program across multiple properties, ensuring exceptional guest experiences and adherence to health standards. Lead teams to exceed brand expectations while dri...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$89K - $120K *

Transform your sales career by driving revenue growth through strategic partnerships. Manage the full sales cycle, collaborate with teams, and leverage your expertise in cloud computing to attract and...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$82K - $123K *

Drive innovative software solutions by integrating AI capabilities and enhancing user experiences. Collaborate with teams to develop, test, and implement applications, ensuring quality and efficiency...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$88K - $105K *

Contribute to organizational success by partnering with leaders to enhance HR practices, drive employee engagement, and support growth initiatives, ensuring a positive experience throughout the employ...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Transportation

$95K - $115K *

Champion project success by managing SAP OTC enhancement initiatives, ensuring effective planning, stakeholder engagement, and delivery across Agile and Waterfall methodologies while driving continuou...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $135K *

Shape the future of personalized marketing by leading strategy and execution across digital channels. Collaborate with teams to define impactful customer journeys and optimize campaigns for measurable...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Contribute to patient-centered care by delivering professional medical services, exercising autonomy in decision-making, and collaborating with healthcare teams to ensure optimal patient outcomes and...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$120K - $145K *

Transform healthcare data solutions by designing scalable architectures, optimizing data pipelines, and ensuring compliance with regulations. Collaborate with cross-functional teams to deliver high-qu...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Healthcare

$185K - $344K *

Advance enterprise patient intelligence by leading strategy, governance, and analytics. Collaborate across functions to enhance decision-making and drive insights that improve patient outcomes and bus...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$160K - $190K *

Take ownership of financial strategy and operations, leading a dynamic finance team to enhance performance, ensure compliance, and drive growth in a collaborative, employee-owned environment...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Unlock potential by providing expert technical support for enterprise clients. You'll bridge engineering and customer success, resolving complex issues, analyzing system performance, and enhancing cli...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$165K - $264K *

Pioneer cross-functional collaboration to manage IS projects, ensuring successful implementation and support of applications, upgrades, and integrations while overseeing budgets and resources across S...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$180K - $220K *

Shape the future of enterprise technology by leading strategic partnerships and alliances. Drive growth through collaboration with top innovators in software, hardware, and security, while influencing...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$132K - $251K *

Drive the development and delivery of advanced flight management systems, overseeing complex software projects from inception to service. Collaborate across teams to ensure alignment with technical, f...

1 week ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$105K - $150K *

Unlock potential by joining a dynamic team focused on integrating construction technology solutions. Collaborate with customers and partners to enhance workflows, drive adoption, and deliver impactful...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$88K - $111K *

Elevate your career by implementing lease accounting solutions, optimizing client software use, and collaborating with teams to enhance product functionality and documentation. Drive success in enterp...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$84K - $131K *

Lead the charge in developing innovative Java applications, leveraging Spring Boot and DevSecOps practices. Collaborate with cross-functional teams to enhance web-based solutions while integrating AI...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$115K - $150K *

Lead strategic pricing initiatives by developing complex cost models and ensuring compliance with federal regulations. Collaborate across departments to create competitive proposals that drive busines...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$125K - $150K *

Champion innovation by discovering and scaling new business opportunities. Collaborate with Sales and customers to prototype solutions, turning insights into market-ready products that drive growth an...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $100K *

Elevate your career by driving growth through strategic client relationships, managing a robust sales pipeline, and collaborating with cross-functional teams to achieve revenue targets in a fast-paced...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$152K - $253K *

Empower healthcare delivery by leveraging health information technology to enhance patient care. Collaborate with health systems and cross-functional teams to align technology with clinical workflows...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$152K - $253K *

Drive health informatics initiatives to enhance care delivery across diverse healthcare systems. Collaborate with stakeholders to align technology solutions with clinical workflows, ensuring complianc...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$152K - $253K *

Transform healthcare delivery by leveraging health information technology to enhance patient care, streamline clinical workflows, and improve operational efficiency across diverse health systems and t...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$152K - $253K *

Transform healthcare delivery by leveraging health information technology to enhance patient care and operational efficiency. Collaborate with health systems and cross-functional teams to align techno...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $190K *

The Consulting Manager for Workday Benefits will lead teams in delivering complex implementations and system optimizations for Workday Benefits. This role requires expertise in benefits administration...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.