Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,016

Sort By: Relevance

$95K - $115K *

Drive operational excellence by leading maintenance strategies and capital projects, enhancing asset reliability and performance in a fast-paced food manufacturing environment. Collaborate with cross...

1 week ago

  •   8 - 10 years exp.  •   Food & Beverages

$88K - $105K *

Champion team success by leading network contracting initiatives, optimizing processes, and fostering collaboration across departments. Drive performance and development while enhancing stakeholder re...

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$125K - $150K *

Join a team that's redefining asset management through innovative Oracle ERP solutions. Lead enterprise-level systems engineering to enhance financial accuracy and streamline processes, ensuring compl...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$157K - $174K *

Join a team that's shaping the future of combat vehicle software. Lead architectural design and technical direction for mission-critical systems, integrating advanced technologies in a collaborative...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$150K - $200K *

Drive strategic revenue growth by engaging C-suite stakeholders and closing multimillion-dollar partnerships within large pharmaceutical organizations. Leverage your expertise to navigate complex sale...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$166K - $200K *

Shape the future of healthcare technology by leading engineering for patient-centric systems. Drive innovation, ensure compliance, and mentor teams to deliver safe, efficient clinical solutions that e...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Healthcare

$90K - $110K *

Elevate your career by managing a diverse portfolio of retail and industrial properties across multiple states. This hands-on role focuses on operational excellence, financial performance, and tenant...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$100K - $140K *

Grow your career with a dynamic role in clinical support, training surgical teams, and ensuring optimal patient outcomes in complex procedures. Collaborate closely with medical professionals, manage i...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Engage in cutting-edge AI development by designing and scaling intelligent applications. Leverage Generative AI and modern tools to enhance productivity and integrate workflows within healthcare platf...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$87K - $293K *

Unlock transformative product experiences by leading end-to-end design projects, driving strategic client engagement, and mentoring future design leaders, all while leveraging AI tools to enhance desi...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Business Services

$155K - $200K *

Elevate product management by driving vision, strategy, and execution across digital solutions in clinical development. Collaborate with cross-functional teams to enhance user experience and operation...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$103K - $184K *

Transform compliance processes by leading IT SOX initiatives, ensuring robust internal controls and regulatory adherence across the organization while collaborating with cross-functional teams to miti...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Transportation

$80K - $95K *

Grow your career by embracing creativity and innovation in architecture. Collaborate with a passionate team to provide unique solutions that enrich communities and deliver projects showcasing pride an...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$90K - $150K *

Lead your career with a pivotal role in strategic sales, driving revenue through exceptional account management and cultivating strong relationships with agencies and clients to expand our innovative...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $145K *

Unlock potential by managing and optimizing data and BI platforms. Collaborate with stakeholders to define architecture, drive project plans, and ensure data quality while leading a team to deliver im...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$140K - $180K *

Lead the execution of complex IT infrastructure projects, ensuring mission success for critical U.S. Coast Guard programs. Collaborate with stakeholders and manage resources to deliver seamless techno...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Information Technology

$159K - $186K *

Shape the future of leadership and organizational development by driving enterprise strategies that enhance workforce capabilities, succession planning, and organizational effectiveness. Collaborate w...

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$170K - $210K *

Unlock potential by driving strategic initiatives in oncology sales, fostering relationships with key stakeholders, and ensuring patient access to innovative therapies while achieving business goals t...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$200K - $250K *

Lead the charge in managing complex financial services litigation, providing strategic guidance to clients while collaborating with a dynamic team. Drive case resolution and compliance efforts in a fa...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Legal & Accounting

$80K - $95K *

Join a dynamic team to leverage your scientific expertise in enzymes and animal nutrition. Collaborate across departments to design trials, solve customer challenges, and drive product innovation whil...

1 week ago

  •   Less than 5 years exp.  •   Food & Beverages

$120K - $145K *

Transform your career by driving VAR growth across North America. Lead partner recruitment, develop strategic plans, and enhance sales execution to achieve sustainable revenue growth in the mid-market...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Consumer Technology

$80K - $145K *

Join a team that's advancing data analytics for VA modernization initiatives. Utilize SQL and Python to drive AI-enabled insights, enhance operational workflows, and support decision-making through ri...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$130K - $150K *

Engage as a cybersecurity advisor, ensuring secure, scalable cloud systems for an Army program. Collaborate with technical teams to maintain security artifacts, assess risks, and integrate security in...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$94K - $114K *

Support project risk management initiatives across various sectors, collaborating with stakeholders to identify, analyze, and mitigate risks. Lead qualitative and quantitative assessments to enhance p...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Technical Services

$90K - $110K *

Engage with us to lead the proposal development lifecycle, ensuring compliance and quality in federal government submissions. Collaborate with diverse teams to drive success in a dynamic small busines...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Technical Services

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.