Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$140K - $150K *

Join a team that's dedicated to transforming addiction treatment through telehealth. Collaborate with physicians to provide comprehensive care for patients with substance use disorders, ensuring a sup...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $180K *

Transform digital healthcare services by designing and deploying scalable machine learning models. Collaborate with cross-functional teams to enhance predictive capabilities and ensure compliance with...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$108K - $130K *

Drive successful battery energy storage projects by managing installations, ensuring quality, and maintaining customer satisfaction. Collaborate with cross-functional teams to deliver projects on time...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$184K - $200K *

Unlock potential by driving the vision and strategy for innovative products that empower independent candidates and enhance user engagement. Collaborate with cross-functional teams to create scalable...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Business Services

$130K - $150K *

Elevate client delivery by leading implementation teams, ensuring satisfaction and operational excellence across multiple projects while fostering strong relationships and driving continuous improveme...

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$81K - $98K *

Advance your career by leveraging your public health expertise and Salesforce skills to develop impactful solutions. Collaborate with a dedicated team to enhance public health technology, ensuring it...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$210K - $250K *

Transform client relationships and drive AI-led growth in the Consumer Products, Manufacturing & Retail sectors. Lead strategic accounts, mentor teams, and shape innovative solutions to enhance busine...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Information Technology

$325K - $343K *

Lead the charge in shaping the product vision and strategy for consumer panel and behavioral measurement solutions, driving growth through innovative AI-native practices and client collaboration...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Enterprise Technology

$205K - $255K *

Join a team that's shaping the future of data protection by leading the Computer Backup engineering team. Drive technical direction, manage budgets, and enhance collaboration across desktop and backen...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$105K - $130K *

Elevate patient care by managing clinical support for monitoring systems. Lead diverse teams to enhance customer relationships and ensure effective product utilization post-implementation, driving cli...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $115K *

Optimize quality analytics and reporting for program deliverables, ensuring compliance with standards and client expectations. Collaborate with senior leaders to provide actionable insights and drive...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $200K *

Champion technical evaluations by partnering with sales to showcase AI solutions, architect tailored implementations, and drive successful customer engagements, ensuring prospects experience the full...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$75K - $90K *

Transform client objectives into impactful paid social strategies. Oversee campaign execution, optimize performance, and mentor junior team members while driving cross-functional collaboration to achi...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$130K - $160K *

Lead all HR functions in a dynamic biotech environment, enhancing employee experience and compliance while driving scalable processes and supporting leadership. Engage with teams to foster growth and...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$108K - $130K *

Lead a team of engineers in transmission planning, collaborating with regional organizations to enhance grid reliability and resilience while ensuring compliance and developing strategic expansion pla...

1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$72K - $90K *

Optimize customer journeys by owning lifecycle initiatives, translating strategy into actionable requirements, and driving performance improvements. Collaborate with cross-functional teams to enhance...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$86K - $165K *

Lead the charge in developing cutting-edge embedded cryptographic software for military communications. Collaborate with cross-functional teams to enhance security and reliability while managing Agile...

1 week ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$100K - $120K *

Contribute to the development of our sales team by implementing systems for skill enhancement, performance tracking, and strategic field execution, aiming for excellence in agency collaborations and m...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $120K *

Accelerate progress at clinical sites by enhancing patient recruitment strategies and supporting Oncology studies. Collaborate with teams to optimize enrollment processes and ensure effective communic...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$93K - $117K *

Join a team that's shaping data-driven decisions by building robust analytics models, collaborating with stakeholders, and ensuring data integrity. Leverage your expertise in SQL and BI tools to empow...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$190K - $200K *

Lead the charge in executing capital markets strategies for debt financings, managing end-to-end deal processes, and collaborating across teams to ensure compliance and reporting for a growing portfol...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$132K - $302K *

Partner with us to drive AWS-focused business development, enhancing market strategies and fostering relationships. Lead demand generation and sales origination efforts while managing key partnerships...

1 week ago

  •   8 - 10 years exp.  •   Business Services

$78K - $103K *

Champion accurate coding by interpreting diagnoses and resolving claim errors in this remote role. Leverage your expertise to ensure compliance with CPT, ICD-10, and HCPCS standards while collaboratin...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$187K - $235K *

Lead and manage diverse client engagements, driving business improvement and strategic initiatives across various industries. Collaborate with teams to deliver results while fostering professional dev...

1 week ago

  •   5 - 7 years exp.  •   Business Services

$95K - $115K *

Drive the resolution of complex surety disputes by conducting technical analyses, collaborating with consultants, and advising on construction and claims management, while leading teams to assess risk...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.