Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$80K - $95K *

Tackle customer complaints and drive quality improvements in oligonucleotide products. Collaborate cross-functionally to ensure compliance and enhance customer satisfaction through effective investiga...

1 week ago

  •   Less than 5 years exp.  •   Business Services

$287K - $359K *

Drive growth as you cultivate federal accounts, enhance sales strategies, and facilitate large, strategic deals. Leverage your expertise to position mission-critical solutions in a competitive landsca...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $120K *

Champion your career as a Senior Accountant, overseeing key accounting processes, month-end close, and financial reporting. Collaborate with cross-functional teams to enhance workflows and lead an off...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Media

$125K - $135K *

Drive the evolution of critical DNS infrastructure, ensuring operational excellence, collaborating across teams, and enhancing production services through automation and API development...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$78K - $92K *

Lead the charge in managing a diverse banking product portfolio, driving strategic initiatives, enhancing customer experiences, and collaborating across teams to innovate and implement solutions that...

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $95K *

Lead the charge in optimizing client waste and recycling programs, ensuring savings and compliance while managing supplier relationships and client interactions. Drive strategic improvements and enhan...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$150K - $180K *

Innovate the future of architectural strategy by leading technical direction, fostering collaboration across teams, and driving scalable solutions that align with business goals while mentoring senior...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Healthcare

$160K - $215K *

Empower innovation by designing and prototyping product experiences, collaborating closely with cross-functional teams to enhance user workflows and drive product evolution from concept to execution...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$90K - $120K *

Join a team that's dedicated to advancing process engineering in Life Sciences. Lead complex design projects, collaborate with multidisciplinary teams, and mentor junior engineers while enhancing your...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$150K - $224K *

Unlock potential by engaging with healthcare stakeholders to enhance patient outcomes through strategic medical insights and collaboration within the CNS ecosystem, driving effective utilization of Ot...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$135K - $160K *

Empower startups to achieve rapid compliance with Vanta's AI-driven solutions. As a Staff Product Designer, you'll shape the customer experience from onboarding to activation, driving product strategy...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$85K - $95K *

Oversee the quality assurance of case reviews, ensuring accuracy and completeness in documentation while collaborating with clinicians to uphold high standards in healthcare determinations and workflo...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $330K *

Champion large-scale SAP transformations, driving business outcomes through strategic leadership and innovative delivery. Collaborate with executives to align teams and ensure successful program execu...

1 week ago

  •   11 - 15 years exp.  •   Business Services

$110K - $120K *

Shape the future of marketing strategy for a premier industry expo, driving attendance and engagement through innovative campaigns and cross-functional collaboration. Lead a dynamic team to enhance br...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$130K - $160K *

Transform business challenges into innovative solutions by leveraging AI and engineering expertise. Collaborate with stakeholders to identify opportunities, develop full-stack applications, and drive...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$145K - $205K *

Drive authorization optimization by leading strategy and delivery for payments and fraud decisioning. Collaborate with engineering and data science to enhance transaction performance and recover reven...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$120K - $140K *

Drive efficiency by automating GTM processes, enhancing lead management, and integrating systems. Collaborate with Sales and Marketing to eliminate manual tasks and improve data accuracy, ensuring a s...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$125K - $142K *

Unlock potential by leading clinical trial monitoring efforts, ensuring compliance and data integrity while collaborating with study teams. Your expertise will enhance patient safety and contribute to...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$205K - $341K *

Unlock your potential by leading regulatory strategies for advertising and promotion. Collaborate with cross-functional teams to ensure compliance and drive successful commercialization initiatives in...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Engage in shaping a robust Environmental, Health, Safety, and Sustainability culture across 2,200+ retail locations. Collaborate with leadership to ensure compliance and drive operational excellence t...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Engage with national accounts to drive sales and enhance customer satisfaction. Leverage local relationships and coordinate with internal teams to implement strategic growth plans in the fleet busines...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$188K - $230K *

Join a team that's driving innovation in data center materials. You'll manage strategic accounts, lead complex negotiations, and collaborate with global teams to enhance customer relationships and dri...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$110K - $120K *

Develop your career by providing technical support and consulting to ensure successful customer integration of complex bolting solutions. Collaborate with teams to meet customer needs through effectiv...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$108K - $162K *

Innovate in a strategic sales role, managing key accounts and driving revenue growth. Leverage technical expertise to build relationships and influence decision-making across the F5 solution portfolio...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$169K - $254K *

Lead and optimize the Solutions Engineering team in the Healthcare sector, focusing on technical sales and strategic planning. Drive team performance, manage recruitment, and ensure alignment with com...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.