Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$80K - $100K *

Drive the success of clinical trials by overseeing compliance with regulations and protocols. Engage in site management, monitor data integrity, and ensure patient safety while collaborating with site...

Iowa, USRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$117K - $157K *

Lead the charge in developing and executing a comprehensive content strategy that enhances brand reputation and drives market leadership, while overseeing a team focused on thought leadership, researc...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$130K - $160K *

Lead the charge in project quality management, ensuring compliance with ISO standards and fostering a culture of safety and excellence. Collaborate with diverse teams to drive continuous improvement a...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Energy & Utilities

$100K - $120K *

Lead the charge in expanding market presence for cutting-edge hospitality tech solutions across North America. Drive new business sales, build relationships, and collaborate with teams to achieve reve...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$66K - $110K *

Lead and develop a high-performing unit, ensuring accountability and compliance while managing daily operations to meet service goals. Foster team cohesion and drive results through coaching, training...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Lead the charge in enhancing claims support and customer relationships by managing a high-performing team, ensuring service excellence, and driving operational improvements across Workforce Benefits p...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$74K - $96K *

Join a dynamic team to lead environmental services, ensuring safety and efficiency while managing operations and team development. Drive compliance and foster a culture of continuous improvement in a...

1 week ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$48K - $120K *

Unlock potential by joining a dynamic sales team focused on construction equipment. Drive growth through customer engagement, technical expertise, and strategic account management while enjoying limit...

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$148K - $175K *

Join us to drive product strategy and execution for FP&A workflows, enhancing planning, reporting, and automation. Collaborate across Finance and Engineering to improve systems and user experiences, e...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$130K - $200K *

Drive impactful design and development of front-end features, owning the code from concept to production. Collaborate with teams to establish design systems and set direction for user-centric products...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$95K - $115K *

Transform healthcare delivery by leveraging your Epic Cadence expertise to design, build, and optimize scheduling workflows. Collaborate with teams to ensure successful project outcomes and enhance pa...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Unlock your potential as a senior Epic Willow Analyst, leading pharmacy workflow configurations and supporting clinical applications in a dynamic healthcare environment. Collaborate with teams to opti...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$65K - $100K *

Lead the sales process in the AEC industry, driving growth through relationship-building and consultative selling. Own your territory, generate leads, and deliver impactful software solutions that enh...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$88K - $110K *

Grow your career with a dynamic role focused on managing agricultural loan relationships, ensuring portfolio quality, and fostering strong connections with farmers and agribusinesses to drive profitab...

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$95K - $115K *

Shape the future of air traffic management by leading a team of specialists, optimizing operations, and enhancing safety protocols in a dynamic terminal environment. Drive performance and foster profe...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Transportation

$252K - $365K *

Lead the charge in transforming deal governance and renewal operations, driving efficiency and strategic growth across global commercial processes. Collaborate with cross-functional teams to enhance p...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Consumer Technology

$110K - $130K *

Join a team that's committed to enhancing environmental, health, and safety standards across multiple sites. Lead audits, provide hands-on support, and drive compliance initiatives while collaborating...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$114K - $145K *

Champion the modernization and performance of enterprise applications, ensuring reliability and security while driving innovation and operational excellence in a remote leadership role focused on stra...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$120K - $130K *

Drive the design and implementation of complex software solutions, providing technical leadership and mentorship. Collaborate with cross-functional teams to enhance system architecture and ensure high...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$95K - $105K *

Join a dynamic team to coordinate supplier management, drive contract workflows, and ensure compliance in clinical studies. Collaborate with cross-functional teams to enhance supplier processes and su...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$160K - $180K *

Drive impactful regional marketing strategies that enhance customer engagement and pipeline growth across the Americas. Collaborate with global teams to create tailored campaigns and support sales ini...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Business Services

$110K - $130K *

Advance mechanical systems readiness by overseeing commissioning, conducting site inspections, and ensuring operational efficiency across critical infrastructure. Collaborate cross-functionally to enh...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$115K - $125K *

Drive the development and management of virtual health services, enhancing operational excellence and patient experience while scaling innovative care models across the organization. Lead strategic in...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Accelerate progress at our organization by leading AI initiatives that transform business processes across departments, focusing on operational efficiency and measurable outcomes in Accounting and Fin...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$205K - $240K *

Elevate technology strategy and operations for North America's supply chain, leading engineering teams to optimize platforms and processes. Drive innovation in order management and logistics while ens...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.