Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$85K - $100K *

Drive clinical excellence by partnering with agency leaders to assess, develop, and deliver tailored education programs for nursing staff, ensuring compliance and enhancing patient care across a netwo...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$223K - $313K *

Shape the future of behavioral health care strategy and operations. Leverage your medical expertise to enhance quality, operational efficiency, and patient outcomes while navigating complex regulatory...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$123K - $207K *

Elevate enterprise systems by leading design and enhancements, ensuring reliability and usability. Collaborate with cross-functional teams to translate requirements into scalable solutions while drivi...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$200K - $250K *

Unlock the potential of Open Source and AI governance by leading a multidisciplinary team to ensure compliance, drive best practices, and foster innovation across the enterprise, while collaborating w...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$108K - $130K *

Contribute to the development of innovative web applications using .Net, Angular, and SQL. Collaborate with a dynamic team to enhance existing systems and design new solutions, ensuring high-quality s...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$100K - $125K *

Champion data engineering excellence by designing and maintaining robust data pipelines and analytics solutions. Collaborate with stakeholders to enhance data quality and support enterprise-level data...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $130K *

Optimize the employee experience through innovative engagement strategies and precise HR operations. Be a key player in fostering a vibrant culture while ensuring operational excellence in onboarding...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$104K - $161K *

Accelerate progress at driving agency relationships and revenue growth in the commercial trucking sector. Manage a diverse portfolio of accounts while implementing best practices to enhance sales perf...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$77K - $118K *

Drive impactful design projects by leveraging your drafting expertise in a collaborative environment. Engage with multi-disciplined teams to create precise technical drawings and enhance your skills i...

1 week ago

  •   8 - 10 years exp.  •   Technical Services

$150K - $180K *

Join us to tackle complex challenges as a strategic technical leader, influencing product direction and driving customer success. Your expertise will shape innovative solutions while engaging directly...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$120K - $145K *

Help us ensure high-quality decision-making by collaborating with leaders to frame strategies and analyze options, driving impactful decisions that align with organizational goals and values while fos...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$77K - $135K *

Join us to manage a diverse portfolio of 90-120 real estate assets, ensuring lease compliance and fostering strong landlord relationships while solving complex challenges across North America...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$75K - $90K *

Shape the financial landscape by analyzing data and preparing comprehensive reports. Collaborate across departments to ensure compliance and streamline processes, contributing to efficient financial o...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$98K - $134K *

Champion user-centered design as a Senior Product Designer, leading onboarding experiences that empower educators and learners. Collaborate across teams to create intuitive, impactful solutions that s...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Transform developer experiences by designing intuitive growth-focused products. Collaborate with a dedicated team to enhance usability, streamline onboarding, and boost retention for impactful voice-d...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$135K - $169K *

Unlock your potential as you design and enhance go-to-market programs that drive sales productivity and revenue growth. Collaborate with cross-functional teams to translate strategy into actionable in...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Transportation

$120K - $145K *

Champion data migration initiatives by leading analysis, strategy development, and execution. Collaborate with project teams to ensure quality and governance across large-scale projects, driving effic...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Champion project success by leading clinical trials from initiation to closure, ensuring compliance with budgets, timelines, and regulations while fostering collaboration among stakeholders and team m...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Elevate your sales career by driving enterprise accounts through consultative selling. Collaborate with marketing leaders, manage complex deals, and leverage a supportive team to achieve your targets...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$100K - $135K *

Tackle the full sales cycle by winning new logos and expanding accounts. Drive pipeline growth through outbound prospecting and inbound leads, while shaping go-to-market strategies in a dynamic, remot...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$46K - $122K *

Lead the charge in developing pricing strategies and financial models for PBM client contracts. Collaborate with sales and account teams to optimize revenue and profitability while presenting analyses...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$112K - $130K *

Champion the operational excellence of Dynamics 365 Customer Engagement, ensuring platform stability and usability. Collaborate across teams to enhance processes and drive continuous improvement in a...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$300K - $350K *

Engage in a dynamic sales role, driving the full cycle from pipeline generation to closing six-figure deals in mid-market and enterprise cybersecurity. Contribute to go-to-market strategies and build...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$90K - $105K *

Lead the charge in enhancing quality assurance and performance oversight by analyzing requirements and deliverables, ensuring alignment with contractual standards, and driving process improvements for...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$88K - $110K *

Shape the future of life product development by performing complex actuarial calculations, modeling, and compliance functions. Collaborate across teams to ensure accurate implementation and provide cr...

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.