Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$112K - $179K *

Lead the design and implementation of enterprise identity security and privileged access management, ensuring robust controls for privileged accounts and sensitive access across systems and cloud envi...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$66K - $106K *

Join us to ensure compliance and security for mainframe systems, overseeing policies and audits while collaborating with teams to enhance information security practices and support client needs effect...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$104K - $166K *

Lead the charge in optimizing and securing mission-critical SQL Server databases on AWS. Provide technical expertise, mentor junior staff, and ensure compliance while collaborating with cross-function...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$66K - $106K *

Shape the future by collaborating with stakeholders to analyze and document system requirements, ensuring clarity and consistency across products while enhancing functionality and user experience in a...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$104K - $166K *

Optimize your career by ensuring the performance and scalability of critical AWS platforms. Collaborate with cross-functional teams to deliver secure, automated solutions while enhancing operational e...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$112K - $179K *

Lead the charge in managing complex IT projects from concept to implementation, ensuring timely delivery and compliance with federal standards. Collaborate with stakeholders to drive project success i...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$112K - $179K *

Join a team that's shaping enterprise security architectures to protect vital information systems. You'll design, govern, and implement security solutions across diverse environments, ensuring complia...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$101K - $126K *

Drive the development and execution of clinical programs, ensuring effective support, education, and coordination across departments while managing health outcomes and utilization data for continuous...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$88K - $143K *

Join our Public Works team as a Project Engineer, where you'll design municipal infrastructure, engage with clients, and mentor junior staff across diverse projects in the public sector. Your expertis...

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$88K - $143K *

Grow your career with a dynamic Public Works team, engaging in diverse municipal projects. Collaborate with clients and mentor junior engineers while contributing to impactful community infrastructure...

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$88K - $143K *

Join a team that's dedicated to enhancing public infrastructure through innovative engineering solutions. Collaborate with local clients on diverse projects, from utilities to parks, while mentoring j...

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$88K - $143K *

Transform public infrastructure by leading diverse projects in utilities, roads, and parks. Collaborate with clients and mentor junior engineers while ensuring compliance and technical excellence in a...

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$90K - $125K *

Lead the development and submission of federal proposals, managing teams and resources to deliver compliant, compelling responses. Collaborate with cross-functional teams to ensure alignment with cust...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Technical Services

$150K - $180K *

Empower a high-performing sales team to drive strategic growth and customer engagement in the biopharma sector. Lead complex sales initiatives, build executive relationships, and translate business st...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$101K - $174K *

Elevate your career by joining a dynamic team to design, deploy, and optimize a secure cloud-native platform. Collaborate across functions to enhance delivery pipelines and ensure reliability in a fas...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$92K - $158K *

Join a team that's dedicated to enhancing a secure PaaS for federal applications. You'll troubleshoot complex issues, support tenant operations, and collaborate on platform improvements, ensuring reli...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$110K - $130K *

Join a team that's dedicated to driving growth in healthcare accounts. Leverage your strategic sales expertise to build relationships, identify opportunities, and deliver value in a fast-paced environ...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $120K *

Champion technical integration efforts with partners, ensuring alignment with requirements while delivering enablement and support. Collaborate with sales and engineering teams to drive successful par...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $120K *

Drive enterprise-level revenue growth by building relationships with healthcare executives, identifying strategic opportunities, and delivering tailored solutions to meet sales goals in a dynamic heal...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$95K - $115K *

Join a team that's dedicated to enhancing employee experiences globally. Lead HR partnerships, support managers through change, and drive engagement initiatives while managing complex employee relatio...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$103K - $121K *

Lead and manage the Learning Delivery function, ensuring effective training solutions and employee readiness through strategic planning, quality oversight, and team development. Collaborate with stake...

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$90K - $105K *

Elevate leadership and organizational effectiveness by designing and implementing innovative development programs. Collaborate with stakeholders to identify needs and deliver scalable solutions that e...

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$95K - $110K *

Lead financial management and analysis efforts to support strategic planning and budget execution for DHS initiatives, ensuring alignment with mission priorities and stakeholder requirements while dri...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$100K - $120K *

Support public health initiatives by managing community grant portfolios, providing technical assistance, and enhancing local coalitions' capacity to prevent youth substance use. Collaborate with stak...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$100K - $150K *

Lead project management initiatives to enhance organizational effectiveness, support strategic planning, and coordinate resources across divisions. Utilize strong analytical skills to respond to high...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Aerospace & Defense

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.