Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.
Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.
Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.
Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.
Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.
Average Salary: $110,033
$250K - $500K+*
Optimize and innovate software kernels for hardware integration, collaborating with ML Research and Hardware Engineering teams to enhance performance and efficiency in cutting-edge technology applicat...
1 week ago
Senior Software Engineer, Platform Infrastructure
$165K - $225K *
Elevate infrastructure capabilities by designing and implementing a unified platform that integrates bare-metal servers, storage, and networking for large-scale computation and AI workloads, ensuring...
1 week ago
$100K - $120K *
Champion growth by owning the full sales cycle, educating clients, and driving custom part sourcing for hardware companies. Collaborate with a remote team to deliver exceptional service and build last...
1 week ago
$170K - $200K *
Transform customer experiences by providing technical expertise and solutions. Collaborate with sales and engineering teams to deliver impactful product demonstrations and address technical challenges...
1 week ago
Clinical Trial Manager/Senior Clinical Trial Manager
$110K - $200K *
Join a team that's dedicated to advancing clinical research by leading operational aspects of trials, ensuring compliance with protocols and regulations, and fostering collaboration among stakeholders...
1 week ago
Sr Manager, Payroll Connection & Integration Support
$135K - $145K *
Lead the charge in optimizing payroll integration operations, managing teams, and driving strategic alignment across functions. Elevate customer experience through data-driven insights and innovative...
1 week ago
Sr. Software Engineer - Stacklok Enterprise
$189K - $231K *
Innovate and shape the future of AI platforms as a Senior Engineer, designing and building critical subsystems for enterprise Kubernetes environments. Collaborate with customers and mentor engineers t...
1 week ago
Director, Market Access - Commercial Coverage & Reimbursement
$187K - $281K *
Redefine market access strategies by leading payer engagement to enhance patient access to genomic testing. Collaborate cross-functionally to drive favorable coverage and reimbursement policies, ensur...
1 week ago
Senior Field Engineer, Data Center Design and Engineering
$320K - $405K *
Transform the future of data center engineering by resolving on-site technical issues, collaborating with contractors, and ensuring project success through effective problem-solving and communication...
1 week ago
Network Implementation Program Manager-Des Moines, IA
$70K - $116K *
Drive the successful implementation of large-scale telecommunications projects, ensuring quality, accuracy, and timely delivery. Collaborate cross-functionally to manage risks, validate deliverables...
1 week ago
$130K - $160K *
Create impactful solutions as a Senior Product Engineer, owning projects from concept to delivery. Collaborate with a dynamic team, leveraging AI tools to enhance development while mentoring peers and...
1 week ago
Software Engineer 4/5 - Data and Feature Infrastructure, AI Platform
$466K - $500K+*
Elevate your career by building a cutting-edge ML data platform that enhances productivity for ML practitioners. Collaborate with experts to create innovative solutions for feature computation and sha...
Reposted 1 week ago
Clinical Practice Leader (CPL) -Emergency Medicine (University Campus)
$88K - $105K *
Transform patient care in Emergency Medicine by leading clinical practice, enhancing outcomes, and fostering innovation. Collaborate with a multidisciplinary team to implement evidence-based standards...
1 week ago
$94K - $224K *
Shape the future of learning design by collaborating with clients and partners to create tailored educational solutions. Leverage your expertise to ensure high-quality instructional frameworks that me...
1 week ago
Senior Product Manager - Fraud
$200K - $250K *
Champion the evolution of fraud prevention strategies, enhancing customer experience while safeguarding against risks. Collaborate cross-functionally to design innovative solutions that balance securi...
1 week ago
Dealer Development Manager (Portland, OR)
$80K - $95K *
Join a dynamic team as you develop and maintain dealer partnerships, driving growth and enhancing customer satisfaction in the auto finance sector. Leverage your expertise to navigate market trends an...
1 week ago
$95K - $160K *
Elevate your career by supporting senior leaders in a dynamic tech environment. Manage complex calendars, coordinate travel, and streamline processes to enhance productivity and drive success across g...
1 week ago
$100K - $120K *
Unlock potential by leading a dynamic SQA team to enhance software quality. Drive testing strategies, mentor team members, and ensure compliance with best practices while managing multiple projects in...
1 week ago
$110K - $125K *
Analyze customer needs and drive product initiatives using AI tools. Own features from discovery to delivery, ensuring alignment with business priorities and quality outcomes while collaborating acros...
1 week ago
Director, Consulting & Advisory Alliances, North America
$150K - $170K *
Join a team that's expanding strategic partnerships with consulting firms to enhance supply chain solutions. Drive growth through collaboration, relationship management, and innovative go-to-market st...
1 week ago
$210K - $230K *
Drive your career with a dynamic role focused on enterprise B2B sales, where you'll cultivate relationships, leverage data insights, and collaborate cross-functionally to close high-value deals in a f...
1 week ago
$122K - $205K *
Drive measurable SEO results by owning key surfaces and experiments, leveraging AI tools for hands-on building, and collaborating across teams to enhance organic growth and visibility in a dynamic, re...
1 week ago
$141K - $196K *
Unlock potential by developing causal machine-learning models to optimize customer offers, analyzing complex data, and translating findings into actionable strategies for enhanced conversion rates acr...
1 week ago
$168K - $232K *
Lead the charge in executing innovative financing strategies for our AI lending marketplace. Collaborate with investors and stakeholders to drive structured transactions, ensuring scalable funding sol...
1 week ago
$120K - $145K *
Unlock potential by leading strategic partnerships and driving growth initiatives. Collaborate cross-functionally to enhance business opportunities and ensure partner success through data-driven insig...
1 week ago
What kinds of $100,000+ jobs are available in Iowa?
Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.
Which Iowa cities have professional jobs listed?
Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.
Are all jobs on this page guaranteed to pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.
How can I find the right high-paying job in Iowa?
Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.