Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$72K - $97K *

Unlock potential by joining our team as a CAD Designer/Technician, where you'll create engineering drawings for civil and infrastructure projects, collaborate with multidisciplinary teams, and mentor...

1 week ago

  •   8 - 10 years exp.  •   Technical Services

$80K - $120K *

Drive project success by coordinating OSP fiber infrastructure initiatives. Oversee planning, execution, and compliance across multiple projects, ensuring quality and timely delivery while collaborati...

1 week ago

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$160K - $246K *

Champion innovative IAM solutions by designing secure software and optimizing SaaS services. Collaborate across teams to embed security practices, conduct threat modeling, and enhance monitoring syste...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$75K - $94K *

Shape exceptional client experiences by leading AV production and design projects. Collaborate across sectors to ensure successful event execution while building lasting relationships and maintaining...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$120K - $145K *

Lead the development of AI-driven document extraction solutions, ensuring accuracy and efficiency. Collaborate with cross-functional teams to prioritize features and manage product roadmaps, driving i...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$92K - $110K *

Join a team that's dedicated to delivering exceptional patient care while driving growth and excellence in optometry. Collaborate with leadership to exceed performance metrics and enhance community pr...

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$193K - $238K *

Unlock potential by driving enterprise sales strategies to acquire new clients. Engage with C-level executives, manage key accounts, and exceed revenue goals while advocating for innovative EHS soluti...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$100K - $120K *

Join a dynamic team as an Associate Optometrist, providing high-quality patient care with professional autonomy. Enjoy flexible scheduling and access to advanced technology in a supportive environment...

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$68K - $131K *

Innovate in the design and development of advanced electronic systems for defense technologies. Collaborate in a lab-centric environment to tackle complex hardware challenges through prototyping, inte...

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$466K - $500K+*

Join a team that's shaping the future of AI by designing and building scalable platforms for large-scale machine learning model training, enhancing performance, and creating user-friendly experiences...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$190K - $250K *

Analyze and evaluate therapeutic opportunities to drive innovation and business development. Collaborate with interdisciplinary teams to assess scientific and commercial viability, ensuring alignment...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Lead the charge in enhancing organizational security by developing security frameworks, assessing controls, and collaborating with technical teams to create a resilient security architecture for moder...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Elevate patient care by overseeing medication safety and efficacy. Collaborate with healthcare teams to ensure accurate prescriptions, resolve drug-related issues, and enhance patient outcomes through...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$150K - $160K *

Champion the evolution of Workday PSA by architecting scalable solutions that integrate finance and operations. Lead major initiatives from design to implementation, ensuring alignment with global sta...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $120K *

Transform customer HR environments by implementing and optimizing AI solutions. Collaborate with clients to configure integrations, troubleshoot issues, and enhance workflows, ensuring seamless deploy...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$185K - $315K *

Join us to shape strategic financial planning and analysis, leveraging AI to enhance forecasting and decision-making. This high-impact role collaborates with executives, driving insights that align wi...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Consumer Technology

$85K - $124K *

Champion innovative project management solutions, guiding teams through configuration, product demonstrations, and stakeholder collaboration to deliver value-driven consulting services that adapt to e...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $150K *

Take ownership of SSP partnerships to optimize programmatic supply, enhance monetization, and ensure compliance. Collaborate with cross-functional teams to drive revenue growth and improve inventory q...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Media

$70K - $110K *

Champion the resolution of complex Tier 3 auto claims, leveraging expertise in investigation, liability assessment, and negotiation to ensure effective outcomes while serving as the primary contact fo...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$200K *

Transform the landscape of life sciences partnerships by driving co-developed deals. Leverage your extensive network and expertise to source, pitch, and close high-value agreements that enhance patien...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Healthcare

$150K - $180K *

Advance healthcare solutions by building executive relationships and driving enterprise sales. Lead the sales lifecycle, develop strategic accounts, and leverage modern tools to optimize revenue growt...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $135K *

Shape client relationships and drive growth by expanding existing accounts, identifying service opportunities, and delivering tailored managed security solutions that enhance compliance and risk manag...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$222K - $278K *

Join a dynamic team to drive enterprise sales, transforming industries through innovative technology. Engage with C-level executives, manage complex deals, and build lasting relationships that impact...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$160K - $180K *

Lead the charge in transforming our payment gateway strategy, driving performance and innovation. Collaborate with cross-functional teams to enhance user experience and ensure compliance while optimiz...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $145K *

Elevate your career by leading the development of high-quality clinical documents for global regulatory submissions. Collaborate with cross-functional teams to ensure data-driven messaging aligns with...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.