Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$95K - $115K *

Transform procurement operations by leading strategy and team management in a regulated manufacturing environment. Drive supplier performance, cost efficiency, and material availability to support pro...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Staffing

$86K - $165K *

Unlock potential by designing innovative electrical hardware for cutting-edge display technologies. Collaborate with cross-functional teams to enhance avionics and ground vehicle displays, ensuring qu...

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$466K - $500K+*

Unlock potential by developing scalable AI/ML model serving infrastructure. Collaborate cross-functionally to enhance performance and availability of high-traffic systems, driving innovation in a dyna...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$156K - $215K *

Empower innovation in advanced networking and enterprise solutions by defining strategic roadmaps and driving product lifecycle planning across high-speed networking, optical technologies, and AI plat...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Transform the Federal landscape by leading enterprise sales efforts, engaging with SES leaders, and driving digital transformation across major accounts. Collaborate with cross-functional teams to ach...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Information Technology

$73K - $98K *

Join a team that's dedicated to excellence in DRG auditing. Leverage your expertise in MS-DRG and APR-DRG coding to ensure accuracy and compliance while working remotely. Enjoy a collaborative environ...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$100K - $175K *

Transform operations by leveraging your expertise in IT and cybersecurity. Collaborate with leaders to enhance processes, drive efficiency, and ensure compliance while mentoring teams and aligning str...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$165K - $225K *

Champion the development of a GPU-accelerated compute platform, enhancing AI training and research capabilities. Collaborate with cross-functional teams to design orchestration systems that optimize r...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$160K - $195K *

Join a team that's redefining account marketing for major clients. Collaborate with cross-functional partners to drive growth, enhance customer engagement, and create tailored marketing strategies tha...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$450K - $475K *

Drive revenue growth by leading a team of Regional Directors, fostering collaboration, and ensuring alignment with company goals. Your leadership will shape the region's success and culture while enha...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $180K *

Grow enterprise SAP relationships by managing key accounts and driving new business. Leverage your expertise to expand client portfolios, develop strategic plans, and ensure client satisfaction while...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$163K - $224K *

Drive strategic planning and execution of acquisitions/divestitures, ensuring seamless integration and value creation across teams. Collaborate cross-functionally to manage milestones, risks, and comm...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$300K - $350K *

Join a team that's dedicated to providing comprehensive colorectal care. Collaborate with a multispecialty team, support patient access, and enhance program growth in a fully integrated health system...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$144K - $240K *

Transform healthcare delivery by leading strategic initiatives and optimizing infusion services. Drive client success through expert guidance, operational excellence, and innovative solutions, ensurin...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $180K *

Transform AI infrastructure by designing and maintaining production-grade systems across multiple cloud providers. Engage in hands-on architecture decisions, ensuring reliability, security, and automa...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$120K - $145K *

Unlock potential by leading pre-sales technical strategies that align solutions with client needs, driving revenue growth and retention through collaboration with sales teams and delivering tailored p...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$63K - $108K *

Lead enterprise accounts with 75+ locations, driving SaaS adoption and maximizing business value. Utilize industry expertise to resolve challenges, enhance client relationships, and support strategic...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$220K - $250K *

Lead the execution of large-scale data center construction projects, ensuring safety, quality, and efficiency. Collaborate with diverse teams to drive project success in a fast-paced environment, leve...

1 week ago

  •   11 - 15 years exp.  •   Real Estate & Construction

$189K - $235K *

Lead the marketing investment strategy, optimizing budget allocation between brand and performance. Collaborate with finance and executive teams to ensure effective spending and measurable returns, dr...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$95K - $115K *

Transform control systems in the field as you analyze PLC code, troubleshoot equipment, and ensure regulatory compliance. Collaborate with internal teams and clients while traveling extensively across...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$220K - $250K *

Take ownership of large-scale data center construction projects, leading teams to ensure safety, quality, and timely delivery. Collaborate with diverse stakeholders in a fast-paced environment to driv...

1 week ago

  •   11 - 15 years exp.  •   Real Estate & Construction

$110K - $140K *

Transform campus public safety through innovative drone solutions, managing full-cycle sales in a competitive market. Build relationships, drive consensus, and leverage AI tools to enhance safety prog...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Consumer Technology

$78K - $85K *

Lead the charge in executing influencer marketing projects from inception to completion, ensuring exceptional client service and strategic solutions while managing timelines, budgets, and cross-functi...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Media

$92K - $110K *

Transform patient care as a Clinical Practice Leader, driving evidence-based practices and enhancing team collaboration in a dynamic Emergency Medicine environment. Lead initiatives to improve outcome...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Champion the accounts payable process by leading a dynamic team, ensuring accuracy and efficiency from invoice receipt to payment. Collaborate across departments to enhance workflows and drive automat...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.