Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,016

Sort By: Relevance

$95K - $115K *

Drive impactful field marketing strategies across EMEA, collaborating with sales and stakeholders to execute integrated campaigns that enhance brand visibility and generate demand, while optimizing pe...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$104K - $136K *

Deliver impactful IAM solutions by managing program roadmaps, coordinating cross-functional teams, and leveraging AI tools to enhance identity and access management processes. Drive collaboration and...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$97K - $131K *

Lead a dynamic sales strategy by managing key accounts and partnerships. Drive revenue growth through effective relationship building and strategic planning while achieving ambitious sales targets in...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Enterprise Technology

$125K - $150K *

Lead the charge in transforming construction management through digital delivery. Collaborate with leadership to set strategic direction, enhance project efficiency, and drive innovation across teams...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Real Estate & Construction

$170K - $195K *

Join a team that's dedicated to optimizing global power generation operations. You'll support fleet management, enhance O&M standards, and drive continuous improvement initiatives across a diverse por...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $124K *

Join a team that's dedicated to enhancing Fire Life Safety programs for the FAA. Leverage your expertise in fire protection engineering to support compliance, develop standards, and conduct assessment...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Technical Services

$131K - $237K *

Shape secure, scalable cloud solutions across AWS, Azure, OCI, and GCP. Collaborate with teams to automate deployments, enhance cloud operations, and mentor engineers while supporting mission-critical...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Technical Services

$61K - $122K *

Join a team dedicated to advancing cancer diagnostics by overseeing EHR HL7 interfaces, providing technical support, and leading integration projects. Collaborate with stakeholders to ensure seamless...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Healthcare

$82K - $149K *

Champion a team of call center agents, ensuring high-quality service delivery and compliance. Provide clinical oversight for at-risk cases while driving operational excellence and fostering a supporti...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Technical Services

$98K - $115K *

Transform customer support by managing AI operations and content quality. Drive improvements in AI agent performance, oversee Help Center accuracy, and ensure seamless content delivery for enhanced cu...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$140K - $150K *

Unlock potential by leading software implementation projects, applying Agile methodologies, and ensuring client satisfaction through effective communication and collaboration with cross-functional tea...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $145K *

Transform enterprise service delivery by leading cross-center operations, enhancing efficiency, and ensuring high-quality IT services across multiple locations. Drive initiatives that improve performa...

United StatesRemote

Reposted today

  •   11 - 15 years exp.  •   Information Technology

$94K - $293K *

Transform utilities finance operations by leveraging SAP FI-CA expertise to enhance customer accounting, streamline processes, and lead innovative projects that drive efficiency and compliance across...

Today

  •   5 - 7 years exp.  •   Business Services

$135K - $180K *

Lead strategic HR initiatives across 600+ stores, enhancing leadership capability and organizational effectiveness while driving talent development and engagement in a dynamic retail environment...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$100K - $120K *

Unlock potential by providing expert XBRL project support, ensuring compliance and accuracy in financial reporting for diverse clients while collaborating across teams to enhance project delivery and...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Consumer Technology

$170K - $200K *

Shape the future of medical affairs by leading a high-performing team of Medical Science Liaisons, driving scientific engagement, and ensuring strategic alignment with healthcare needs while fostering...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Grow your career with us by leading strategic sales initiatives, building relationships with key accounts, and driving business growth in the employer-sponsored health sector. Adapt and thrive in a dy...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Accelerate progress at a leading telecom program by driving automation in engineering activities. Collaborate with cross-functional teams to deliver innovative solutions while managing scope, timeline...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Staffing

$159K - $279K *

Lead the charge in driving transparency and accountability across product portfolios. Collaborate with cross-functional teams to enhance risk management, governance, and operational effectiveness whil...

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$108K - $180K *

Join a team that's dedicated to enhancing non-clinical product performance through data-driven insights. Lead KPI optimization and collaborate with stakeholders to improve user experiences across vari...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Join a dynamic team to drive sales growth in the US SME market, owning the full sales cycle and translating complex fintech solutions into clear business value for diverse clients. Collaborate across...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$150K - $200K *

Drive impactful renewable energy transactions by leveraging financial modeling and structuring expertise. Collaborate with a dynamic team to support capital solutions in tax equity and preferred equit...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$180K - $220K *

Join a team that partners with leaders to enhance organizational performance, drive employee engagement, and implement talent development initiatives in a fast-paced, global environment while supporti...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$300K - $350K *

Transform enterprise sales by expanding Fortune 100 accounts across North America. Collaborate with cross-functional teams to drive growth, enhance customer relationships, and leverage a unique cybers...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$172K - $229K *

Join a dynamic team to enhance autonomous vehicle performance through innovative software tools and metrics. Collaborate cross-functionally to drive technical strategy and ensure data quality, contrib...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Transportation

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.