Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$80K - $95K *

Shape the future of nursing operations by leading a dedicated team, ensuring compliance, and fostering a compassionate care environment that prioritizes resident dignity and independence while driving...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Join our team to lead nursing operations across Iowa, ensuring high clinical standards and regulatory compliance while fostering a compassionate, person-centered care environment for residents and sta...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Drive nursing excellence across Iowa by leading operations, ensuring compliance, and fostering a compassionate care environment. Collaborate with teams to enhance resident experiences and support staf...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Inspire change by leading nursing operations across Iowa, ensuring compliance and high standards of care. Collaborate with teams to enhance resident experiences and drive operational efficiency while...

Ottumwa, IARemote

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Empower nursing excellence by leading operations across Iowa, ensuring compliance and high standards. Champion person-centered care while mentoring staff and enhancing team efficiency to positively im...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

Drive efficiency and scalability in legal operations by optimizing processes, managing technology, and controlling costs. Lead cross-functional projects and enhance compliance initiatives to support t...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Transportation

$110K - $130K *

Optimize project execution by leading a team in Startup and Commissioning activities, ensuring timely delivery, quality standards, and adherence to budget while fostering a safe and collaborative work...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$110K - $130K *

Drive compliance and policy excellence as a Senior HR Advisor, overseeing employee relations, complex cases, and immigration. Collaborate globally to harmonize policies during acquisition, leveraging...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$125K - $150K *

Join a team that's driving growth and innovation in the industry. You'll own P&L, lead strategic initiatives, and foster key customer relationships while managing a dedicated team to achieve ambitious...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$120K - $145K *

Champion innovation by providing legal guidance on digital identity products, ensuring compliance and risk management throughout the product lifecycle. Collaborate with cross-functional teams to navig...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$123K - $247K *

Transform your career by driving digital growth and strategic account management. Collaborate with Core Account Executives to enhance customer relationships and expand our digital portfolio across key...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$80K - $95K *

Lead the charge in enhancing quality assurance practices, ensuring compliance with ISO standards, and driving continuous improvement initiatives across production processes to elevate overall product...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$89K - $134K *

Join a team that's dedicated to sourcing top talent and driving recruitment strategies. In this pivotal role, you'll enhance our hiring processes, build strong candidate pipelines, and ensure a seamle...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Transportation

$150K - $175K *

Lead innovative cloud solutions by architecting and managing robust platforms. Collaborate with a dynamic team to tackle complex challenges in AWS and Azure, enhancing your skills while driving impact...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $95K *

Drive product innovation and commercialization for popcorn products, focusing on microwave varieties. Lead cross-functional teams to translate concepts into scalable processes while ensuring quality...

1 week ago

  •   5 - 7 years exp.  •   Food & Beverages

$115K - $165K *

Innovate by leveraging AI and ML technologies to enhance threat detection and response. As a Senior Consultant, you'll lead deployments, optimize workflows, and support customers in maximizing securit...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$80K - $85K *

Engage with members to enhance their impact goals through strategic account management, ensuring a high-quality experience. Collaborate with Executive Sponsors to drive renewals and expansions while m...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$145K - $276K *

Champion the future of aerospace by leading production and sustainment efforts for critical defense contracts. Engage with cross-functional teams to drive strategy, ensure timely deliveries, and manag...

1 week ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$110K - $130K *

Optimize customer adoption by leading product training and engagement, ensuring successful go-live and sustained usage. Act as a trusted radiology workflow consultant, driving deep product knowledge a...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$108K - $130K *

Elevate your career by managing Computer System Assurance projects, ensuring compliance with global regulations and quality standards. Lead teams to develop validation strategies that guarantee data i...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$155K - $188K *

Elevate employee benefits and retirement programs by leading strategic initiatives, ensuring compliance, and enhancing program effectiveness for a diverse workforce. Collaborate with cross-functional...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$164K - $240K *

Shape global procurement strategies to optimize costs and ensure supply continuity while pursuing innovation in sourcing and sustainability objectives...

United StatesRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Retail & Consumer Goods

$72K - $97K *

Join a dynamic team to support global clinical study delivery, ensuring quality and compliance in clinical operations. Collaborate with cross-functional teams to manage study logistics, data tracking...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Drive global FP&A process excellence by leading budget management, optimizing forecasting, and enhancing reporting standards. Collaborate with finance teams and executive leadership to support strateg...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$125K - $150K *

Empower teams by designing and building scalable, secure systems that enhance performance and reliability. Collaborate across disciplines to innovate with AI while maintaining a security-first approac...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Media

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.