Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$150K - $170K *

Take ownership of strategic finance leadership, optimizing cash flow and credit risk while developing innovative financing solutions to drive profitable growth and enhance operational efficiency acros...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$170K - $220K *

Lead the charge in technology strategy and execution, overseeing software engineering, business systems, and IT. Drive innovation and efficiency while ensuring robust architecture and team development...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Food & Beverages

$145K - $175K *

Transform customer success by managing DHS accounts through the entire lifecycle, ensuring seamless delivery, adoption, and growth of Skydio systems while collaborating with cross-functional teams to...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$104K - $176K *

Lead and develop a high-performing Sales recruiting team across the Americas. Partner with Sales leaders to design scalable hiring strategies, enhance candidate experience, and drive revenue growth th...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$100K - $120K *

Optimize patient care by ensuring accurate medication dispensing and compliance. Collaborate with healthcare teams to provide clinical guidance and maintain high standards in a dynamic pharmacy enviro...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$112K - $179K *

Champion the Agentic AI platform by owning its end-to-end operations, ensuring secure, reliable, and scalable delivery through advanced CI/CD practices, AWS infrastructure, and Kubernetes management...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$207K - $366K *

Lead strategic account management initiatives, driving growth and client satisfaction through innovative solutions and cross-functional collaboration. Shape the future of client relationships by ensur...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Information Technology

$156K - $214K *

Inspire growth by leading an Enterprise CPG sales team, driving strategic partnerships with top-tier brands, and influencing C-suite executives to leverage innovative insights for impactful decisions...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Media

$118K - $180K *

Join a dynamic team as a senior electrical engineer, providing technical leadership in substation design and commissioning. Leverage your expertise to ensure project success through collaboration, ove...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Technical Services

$125K - $150K *

Accelerate growth by leveraging your sales expertise to drive strategic deals for Unified Commerce solutions. Collaborate cross-functionally to enhance product knowledge and execute go-to-market strat...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $95K *

Drive growth by owning the cross-sell pipeline, leveraging data-driven strategies to engage high-volume clients and optimize operations for maximum customer lifetime value. Collaborate with teams to d...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$100K - $120K *

Lead patient care initiatives by filling prescriptions, counseling patients, and supporting pharmacy operations. Collaborate with healthcare teams to enhance wellness programs and community outreach...

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$135K - $160K *

Pioneer a transformative deal desk to empower Sales with streamlined processes, enabling faster, defensible deal-making while collaborating closely with cross-functional teams to enhance pricing strat...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Drive operational excellence as you manage tech stacks and workflows, delivering data-driven insights and aligning cross-functional teams for revenue growth and partner success...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$240K - $270K *

Elevate your career by leading the Sports and Entertainment vertical across North America. Drive customer acquisition and revenue growth through consultative selling and technical expertise, shaping t...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$95K - $115K *

Transform the ScriptMed Cloud Platform by designing and deploying scalable solutions. Collaborate with teams to automate workflows and enhance customer onboarding while ensuring compliance with data s...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $200K *

Lead and shape a high-performing Security Engineering and Operations team, driving proactive threat management and strategic engineering initiatives across North America while enhancing operational ef...

RemoteRemote

1 week ago

  •   11 - 15 years exp.  •   Media

$112K - $338K *

Empower transformation in the insurance brokerage sector by leading multidisciplinary teams, shaping strategic agendas, and driving large-scale technology programs for measurable business outcomes...

1 week ago

  •   8 - 10 years exp.  •   Business Services

$88K - $110K *

Advance your career by leading institutional research and assessment efforts. Oversee data collection, analysis, and reporting to drive informed decision-making and support accreditation processes in...

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$225K - $265K *

Lead the charge in developing a high-performing engineering team focused on firewall validation and security. Drive collaboration across technical and product teams while fostering an inclusive enviro...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$75K - $125K *

Elevate your career by onboarding customers and driving their success through strategic reviews and relationship building. Collaborate with teams to align offerings and ensure a positive experience wh...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Technical Services

$115K - $130K *

Empower client success by managing accounting projects and implementations. Drive efficiency through process improvements and AI tools while ensuring accurate, timely deliverables. Collaborate with te...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Legal & Accounting

$119K - $167K *

Lead the charge in evolving our cloud infrastructure and CI/CD systems. As a Senior DevOps Engineer, you'll enhance security, reliability, and operational efficiency while mentoring a team and ensurin...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$77K - $202K *

Innovate healthcare payer platforms by analyzing complex issues, guiding teams, and enhancing client experiences. Collaborate on modernization efforts, leveraging Epic software to streamline operation...

1 week ago

  •   Less than 5 years exp.  •   Legal & Accounting

$134K - $160K *

Lead the charge in paid social strategy and performance for eCommerce brands. Drive measurable growth, mentor teams, and elevate operational standards while navigating complex client challenges with c...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.