Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$200K - $250K *

Champion supply chain strategy and execution for clinical operations, ensuring timely, compliant delivery of materials for global oncology trials. Collaborate with cross-functional teams to manage ris...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$165K - $195K *

Join a dynamic biotech team to drive strategic initiatives, manage cross-functional operations, and lead business development efforts. Leverage your scientific expertise and leadership skills to shape...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$165K - $200K *

Deliver exceptional user experiences by refining complex tools into intuitive designs. Collaborate closely with engineers to enhance UX, ensuring our LLM platform meets user needs with responsiveness...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Drive customer support excellence by managing a frontline team to ensure timely resolutions, operational efficiency, and a culture of continuous improvement, paving the way for stellar service in heal...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$114K - $191K *

Lead the charge in shaping high-impact SaaS solutions by driving technical strategy and empowering a high-performing engineering team. Collaborate across disciplines to foster innovation in a fast-pac...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Join a dynamic team to deliver innovative design engineering solutions for power projects. Leverage your expertise in mechanical engineering to create impactful designs and ensure project success thro...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$83K - $163K *

Accelerate your career by managing a full sales cycle, from prospecting to closing deals. Engage with the entrepreneurial community and drive revenue growth while building lasting relationships in you...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Business Services

$85K - $103K *

As an Account Executive in-territory in Miami, you will be responsible for managing the full sales cycle, including building and managing a sales pipeline, prospecting, and closing deals. This role re...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Business Services

$72K - $97K *

Transform automation systems by troubleshooting and enhancing PLC and PC controls. Collaborate with maintenance teams to ensure reliability and accuracy in production processes while overseeing upgrad...

1 week ago

  •   Less than 5 years exp.  •   Food & Beverages

$100K - $120K *

Partner with us to enhance relationships with executive partners, enabling pipeline growth and revenue generation. Leverage cross-functional collaboration while managing multiple engagements, driving...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $180K *

Transform client engagement by driving growth in untapped markets, shaping impactful solutions, and delivering measurable results. Collaborate with diverse teams to connect client needs with innovativ...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$107K - $195K *

Join a team that's shaping the future of microgrid automation and renewable energy. Leverage your expertise in control systems and collaborate on innovative projects that drive sustainable energy solu...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Technical Services

$150K - $238K *

Shape the future of digital manufacturing by leading strategic IT and operations initiatives. Drive multi-site transformation, ensuring seamless integration of technology and processes to enhance effi...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$155K - $160K *

Drive the Order-to-Cash strategy, overseeing cash application, collections, and AR performance. Collaborate cross-functionally to optimize cash flow and enhance financial reporting, ensuring timely re...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$156K - $220K *

Unlock your potential by leading the paid media strategy in a transformative role involving creative innovation and team development, driving growth through data-driven decisions across multiple chann...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Media

$65K - $116K *

Drive exceptional client experiences by leading delivery operations, managing relationships, and leveraging analytics to identify service gaps. Collaborate cross-functionally to ensure seamless execut...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$86K - $106K *

Drive advertiser growth by optimizing campaign performance and building strong client relationships. Collaborate with internal teams to enhance product offerings and ensure a seamless advertiser exper...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Consumer Technology

$159K - $168K *

Discover impactful opportunities by leading state and local government affairs in the Midwest, advocating for public policies that enhance community engagement and support the growth of a leading e-co...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$91K - $118K *

Accelerate your career by driving technical solutions and proposals for engineered equipment. Collaborate with sales and engineering teams to ensure customer satisfaction and secure new business oppor...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$87K - $293K *

Lead complex identity governance implementations, guiding teams and clients through design, delivery, and strategy. Own technical vision, manage project scope, and mentor consultants while ensuring co...

1 week ago

  •   5 - 7 years exp.  •   Business Services

$70K - $205K *

Shape identity security solutions by implementing IGA systems, customizing workflows, and solving access challenges. Collaborate with clients and teams to enhance security posture and deliver high-qua...

1 week ago

  •   5 - 7 years exp.  •   Business Services

$193K - $309K *

Join a dynamic team to enhance cloud security capabilities, leading hands-on initiatives and shaping strategic direction. Collaborate across engineering teams to secure AWS environments and mentor pee...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$193K - $309K *

Empower the development of innovative features on a high-traffic Orders platform, collaborating across teams to enhance architecture and tooling, ensuring efficient processing for over 1 billion order...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$75K - $93K *

Join us to develop and deliver impactful training programs that enhance customer engagement and retention. Collaborate with leaders to identify performance gaps and create solutions that drive measura...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$135K - $160K *

Lead data-driven strategies to enhance revenue growth across customer acquisition, retention, and expansion. Collaborate with cross-functional teams to establish integrated metrics and actionable insi...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.