Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$85K - $110K *

Support client retention by managing small employer group accounts, fostering relationships with clients and carriers, and suggesting new coverage options. Collaborate in a remote environment, leverag...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$143K - $179K *

Lead cross-functional initiatives, optimizing governance and operational readiness for programs. Collaborate with stakeholders to enhance portfolio execution, reporting, and PMO capabilities, driving...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K *

Lead the charge in developing innovative full-stack solutions that enhance workflow automation in wealth management. Collaborate with a dynamic team to create impactful features using modern technolog...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Join us to lead generative engine optimization strategies, transforming insights into actionable plans across SEO, content, and digital PR. Collaborate with a dynamic team to enhance client visibility...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$175K - $210K *

Join a dynamic team to lead and define technology strategy, ensuring exceptional engineering execution across multidisciplinary teams while delivering high-quality products that align with business go...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$175K - $200K *

Build innovative interfaces that enhance AI development and observability. You'll design and prototype user experiences that empower AI teams to understand and improve their applications through effec...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$165K - $215K *

Engage with innovative AI/ML teams to drive customer success in leveraging AI. You'll cultivate client relationships, manage adoption, and ensure measurable impacts through tailored solutions and stra...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$160K - $190K *

Engage in building strategic partnerships that drive revenue growth. Collaborate with global tech partners to ensure effective integration and delivery. Lead initiatives that enhance the operational l...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$180K - $230K *

Lead the charge in financial strategy and operational excellence, overseeing corporate finance, property management accounting, and shared services. Drive profitability and efficiency while ensuring r...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$110K - $130K *

Lead the charge in Epic solutions delivery by providing expert support, managing projects, and mentoring team members. Shape the future of healthcare IT by aligning technical teams with stakeholder ne...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Create user-centered designs that enhance complex enterprise workflows. Collaborate with cross-functional teams to deliver intuitive, scalable experiences while driving product strategy and ensuring d...

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Develop and oversee power plant thermal performance analysis, modeling, and testing. Collaborate with teams to ensure accurate data collection and reporting, while supporting project design efforts an...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$109K - $164K *

Empower the Employee Concerns Program by conducting investigations, analyzing data, and promoting a confidential environment for addressing nuclear safety and quality concerns. Collaborate with cross...

1 week ago

  •   Less than 5 years exp.  •   Energy & Utilities

$108K - $130K *

Deliver enterprise-level leadership in nuclear assurance oversight. Lead complex audits, assess supplier compliance, and drive continuous improvement initiatives to enhance nuclear safety and operatio...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$150K - $180K *

Unlock potential by leading client relationships and driving strategic measurement initiatives. Manage a diverse portfolio, ensuring retention and growth while guiding teams to deliver impactful marke...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$100K - $150K *

Drive growth by building strategic partnerships and closing new business opportunities. Utilize a consultative approach to address client needs with innovative out-of-home solutions, while managing yo...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Media

$80K - $95K *

Tackle critical cybersecurity challenges as an Information Assurance Analyst, ensuring compliance and security for key Army systems. Collaborate with technical teams to conduct vulnerability assessmen...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Partner with us to drive data-informed marketing strategies and optimize measurement practices. Leverage your analytics skills to guide clients, enhance performance, and manage a talented team while f...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$106K - $264K *

Lead growth by generating new business and driving revenue through extensive relationship building and sales strategies. Engage with C-level executives in a dynamic, remote environment to exceed quart...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Consumer Technology

$88K - $105K *

Champion marketing operations by owning HubSpot and driving data-driven campaigns. Collaborate with leadership to enhance automation, reporting, and integrations, ensuring seamless operations and impa...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$80K - $95K *

Drive quality excellence by leading the Quality department, ensuring compliance with standards, and fostering collaboration across teams to enhance manufacturing processes and resolve quality issues e...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$80K - $120K *

Unlock potential by optimizing commercial processes through AI and analytics. Collaborate with teams to enhance efficiency, forecasting, and decision-making, driving impactful business outcomes across...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$133K - $155K *

Champion incident response excellence by leading investigations, automating processes, and enhancing security posture in a cloud-native environment. Collaborate with teams to ensure effective incident...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$108K - $162K *

Transform regional marketing efforts by executing targeted programs that align with sales priorities and drive pipeline growth across the U.S. West territory. Collaborate with cross-functional teams t...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$235K - $310K *

Join a team that empowers translational medicine innovation in early-phase oncology, owning strategies from IND-enabling studies to proof of concept. Drive impactful biomarker integration and clinical...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.