Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$72K - $90K *

Shape the future of business travel by managing bid responses and collaborating with teams to ensure high-quality proposals that meet client needs and company standards. Engage with subject matter exp...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Transportation

$82K - $150K *

Drive growth by aggressively prospecting and converting new dental accounts while expanding existing relationships. Utilize a hunter mentality to identify opportunities and position value-oriented imp...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Join a team that's driving innovation by leading cross-functional programs that enhance business engagement and operational efficiency, bridging technology and strategy to support growth in a dynamic...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$150K - $175K *

Drive financial operations and internal controls while leading a remote accounting team. Oversee month-end closes, technical accounting, and ERP transformations to enhance operational efficiency and e...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$113K - $127K *

Transform employee relations by leading investigations, resolving disputes, and advising on best practices. Collaborate with leaders to enhance workplace culture and ensure compliance, driving strateg...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$95K - $115K *

Transform client relationships by leading strategic marketing efforts across eCommerce, retail, and DTC strategies, while ensuring performance aligns with business objectives and driving measurable gr...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Lead innovative marketing campaigns for fashion clients by leveraging digital strategies, optimizing cross-channel efforts, and guiding account teams to drive performance and business growth through t...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$135K - $160K *

Lead a dynamic engineering team to innovate and deliver backend solutions, enhancing our technology's reach. Engage hands-on in coding and architecture while mentoring others, ensuring high-quality so...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Transportation

$79K - $127K *

Engineer robust solutions for Power Delivery projects, ensuring safety and efficiency through hands-on execution, troubleshooting, and training to enhance system performance and drive customer satisfa...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$165K - $180K *

Transform your career by driving new customer acquisition in healthcare. Leverage your expertise to build C-suite relationships and lead complex sales processes, contributing to the growth of a dynami...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Technical Services

$110K - $130K *

Transform vulnerability detection by leveraging innovative technology and research. Join a team dedicated to crafting detection logic to identify critical vulnerabilities, ensuring clients stay one st...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$82K - $137K *

Transform business insights into actionable data solutions by collaborating with stakeholders, analyzing data quality, and ensuring effective integration of analytical products to drive operational ef...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$112K - $135K *

Elevate your career by designing and implementing cloud infrastructure solutions in Azure. Collaborate with teams to automate deployments, optimize CI/CD pipelines, and leverage AI tools for enhanced...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$167K - $230K *

Develop high-performance software for quantum processors, driving architectural decisions, mentoring teams, and tackling complex challenges. Collaborate with interdisciplinary experts to enhance softw...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$220K - $270K *

Join a team that's pushing the boundaries of machine learning in autonomous vehicles. Enhance driving capabilities, lead innovative teams, and drive commercial-scale solutions with cutting-edge techno...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Transportation

$125K - $150K *

Accelerate your career by leading innovative marketing strategies that drive lead generation and revenue growth. Collaborate with cross-functional teams to enhance brand visibility and cultivate a cul...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$125K - $225K *

Unlock innovation by building scalable, user-centric applications in TypeScript and React. Collaborate with engineering teams to enhance AI-driven solutions, ensuring top performance in ML observabili...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $160K *

Champion the design and implementation of scalable data pipelines, ensuring data integrity and availability. Collaborate with cross-functional teams to optimize data workflows and enhance infrastructu...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$116K - $170K *

Join a dynamic team to drive the planning and execution of PLC updates, ensuring seamless operations across automated warehouse sites while coordinating with cross-functional partners and enhancing de...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$108K - $127K *

Transform client relationships by managing global accounts in Media & Entertainment. Drive strategic initiatives, enhance profitability, and foster collaboration across regions while ensuring exceptio...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Transportation

$80K - $95K *

Elevate your career by delivering hands-on UAV training to diverse teams. You'll ensure safe operations, evaluate readiness, and enhance training programs through practical instruction and field insig...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$219K - $277K *

Elevate community oncology practices by driving growth and retention through strategic sales initiatives. Collaborate with cross-functional teams to enhance market presence and deliver tailored soluti...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$88K - $105K *

Join as a key IT partner, ensuring reliable and secure infrastructure for manufacturing and lab operations. Collaborate with stakeholders to implement effective technology solutions and manage multipl...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $170K *

Unlock your potential as a mobile tech lead, guiding teams in delivering innovative apps. Drive best practices in architecture and CI/CD while collaborating with cross-functional teams to align techni...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Consumer Technology

$165K - $265K *

Champion governance excellence by leading policy frameworks, enhancing Board operations, and driving AI-enabled improvements. Engage with investors and committees to elevate governance practices at a...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Consumer Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.