Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$290K - $436K *

Elevate our mobile engineering organization by leading teams, driving modernization, and ensuring app performance and quality. Collaborate with cross-functional partners to innovate and mentor future...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$81K - $110K *

Join a team that's dedicated to providing exceptional patient care through systematic assessments, timely documentation, and effective communication. Shape the future of healthcare by ensuring quality...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$81K - $110K *

Unlock your potential as a Registered Nurse, providing critical care in a supportive environment. Engage with patients during their recovery journey, ensuring compassionate treatment and expert medica...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$87K - $157K *

Lead the charge in designing and reviewing structural components for substation and transmission projects, ensuring quality control and mentoring junior engineers while engaging with clients and suppo...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Technical Services

$185K - $344K *

Transform analytics modernization and productivity by leading strategy, governance, and process evolution. Collaborate with cross-functional teams to enhance workflows, drive AI adoption, and optimize...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$129K - $218K *

Unlock potential by driving strategic sales initiatives and operational improvements. Collaborate with leaders to enhance performance, resource allocation, and growth, transforming data into actionabl...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$125K - $130K *

Join a dynamic team as a Senior Cybersecurity Analyst, focusing on IT service recovery and business continuity. Collaborate with federal staff to develop strategies that ensure operational resilience...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$84K - $187K *

Join the AI Automation team to innovate and implement AI solutions that enhance efficiency and security. Collaborate with experts to build automations, connect systems, and experiment with cutting-edg...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$104K - $191K *

Accelerate progress at the forefront of cybersecurity by driving AI and automation initiatives. Collaborate with security teams to identify opportunities, coach on new tools, and enhance organizationa...

Des Moines, IARemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$165K - $195K *

Lead the charge in developing and managing a robust Enterprise Data Warehouse on Databricks. Drive BI solutions, mentor a team, and ensure data quality while collaborating across departments to enhanc...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$95K - $171K *

Transform client success by delivering tailored support and strategic insights, ensuring seamless onboarding and ongoing engagement with our innovative platform. Leverage your expertise in energy engi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$144K - $210K *

Drive compliance excellence by leading a team focused on identifying and addressing control gaps and violations across financial services, ensuring adherence to regulatory standards while enhancing su...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$80K - $150K *

Empower HVAC technicians by providing expert guidance, training, and support. Drive operational improvements and enhance technician development while enjoying a balanced work schedule and collaborativ...

1 week ago

  •   Less than 5 years exp.  •   Energy & Utilities

$160K - $200K *

Lead the charge in building and guiding a US technical organization, ensuring battlefield-proven products meet US defense standards while fostering collaboration with global teams to enhance customer...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$140K - $200K *

Empower mission-critical federal systems by leading the design and automation of secure cloud platforms. Drive reliability, mentor engineers, and set technical direction in a collaborative environment...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$100K - $120K *

Support senior leaders by providing agile administrative assistance, managing complex calendars, coordinating travel, and optimizing processes to enhance operational efficiency across the organization...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$130K - $160K *

Lead strategic initiatives in cybersecurity sales, driving revenue growth and client engagement with Fortune 1000 customers. Collaborate across teams to deliver tailored security solutions and achieve...

1 week ago

  •   11 - 15 years exp.  •   Information Technology

$130K - $160K *

Transform security sales strategies by collaborating with cross-functional teams to drive revenue growth and deliver innovative cybersecurity solutions to Fortune 1000 clients, ensuring alignment with...

1 week ago

  •   11 - 15 years exp.  •   Information Technology

$122K - $187K *

Unlock growth by driving strategic sales initiatives within assigned accounts. Collaborate with C-suite executives to deliver tailored technology solutions, ensuring exceptional customer experiences w...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $120K *

Join a team that's dedicated to enhancing patient care across multiple pharmacy locations. As a Floating Registered Pharmacist, you'll fill prescriptions, counsel patients, and support pharmacy operat...

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$80K - $95K *

Shape the future of HR by leading regional teams, implementing strategic programs, and enhancing employee engagement across multiple locations. Drive compliance, foster a diverse workplace, and suppor...

1 week ago

  •   8 - 10 years exp.  •   Food & Beverages

$80K - $95K *

Lead electrical service projects from inception to completion, ensuring safety, quality, and customer satisfaction. Collaborate with teams to manage budgets, schedules, and resources while fostering l...

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$180K - $240K *

Join us to build and operate secure infrastructure for federal and partner environments. This hands-on role focuses on Kubernetes, infrastructure as code, and production support, ensuring reliable dep...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$108K - $130K *

Lead and grow sales across the Western U.S. for architectural products. Drive revenue, build high-performing teams, and provide technical support to ensure successful project execution and customer sa...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$125K - $150K *

Transform the banking landscape by driving sales success and building key relationships. Utilize your expertise to develop strategic solutions that meet client needs while achieving ambitious sales ta...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.