Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down
1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$62K - $100K *

Join a team that's dedicated to delivering successful projects by managing small complexity initiatives, ensuring milestones are met, and fostering collaboration across business and IT stakeholders fo...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$72K - $115K *

Transform the future of digital products by managing their lifecycle, optimizing user experiences, and collaborating with cross-functional teams to drive engagement and adoption while ensuring alignme...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$94K - $164K *

Elevate project outcomes by managing medium to high complexity initiatives, ensuring timely delivery, stakeholder engagement, and adherence to best practices throughout the project lifecycle...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$83K - $132K *

Champion operational excellence by leading compliance and process improvements in Utilization Management. Collaborate across teams to identify gaps, drive change, and ensure adherence to regulatory st...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$135K - $160K *

Empower your career as a Principal IAM Engineer, owning the identity control plane and ensuring secure access to sensitive data. Collaborate with cross-functional teams to automate identity processes...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $225K *

Drive the commissioning lifecycle for large-scale data center projects, ensuring seamless coordination among stakeholders. Oversee installation, testing, and compliance with specifications to achieve...

1 week ago

  •   5 - 7 years exp.  •   Technical Services

$109K - $129K *

Take ownership of product development in a dynamic, cross-functional team. Drive AI-assisted innovation from problem framing to launch, focusing on customer outcomes and strategic impact in a hyper-ag...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$85K - $115K *

Shape user-centric digital experiences by collaborating with cross-functional teams to design intuitive products that enhance participant engagement and operational workflows. Drive design from concep...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$266K - $372K *

Join a dynamic Ads Legal team to provide strategic legal guidance on product initiatives, ensuring compliance with evolving regulations while collaborating across functions to drive innovation in a fa...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Media

$104K - $191K *

Empower security teams by driving AI and automation initiatives, enhancing Cyber Security, Governance, and Data Protection. Collaborate, coach, and connect to optimize workflows and reduce risks while...

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$135K - $151K *

Drive product strategy and execution for Patient Experience solutions, enhancing healthcare practices' connection with patients. Lead cross-functional teams, leverage AI, and optimize workflows to imp...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$200K - $250K *

Drive impactful frontend solutions, transforming complex requirements into user-centric, performant interfaces. Collaborate closely with cross-functional teams to enhance the healthcare experience for...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Information Technology

$180K - $240K *

Build innovative software solutions for federal partners, focusing on full-stack development, user experience, and secure integrations. Collaborate with cross-functional teams to deliver impactful app...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$100K - $167K *

Drive efficiency at the intersection of product development and customer engagement by building integrations and automations that empower teams with timely, relevant product knowledge and streamline w...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$67K - $101K *

Lead the charge in enhancing product designs and quality for hydraulic systems. Collaborate with cross-functional teams to resolve issues, drive improvements, and support product lines, ensuring cost...

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$120K - $131K *

Transform IT business processes through analysis and automation, enhancing efficiency and compliance. Leverage tools like Microsoft Power Platform and ServiceNow to align technology with strategic goa...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$91K - $120K *

Drive quality assurance and compliance for GxP computerized systems, ensuring data integrity and regulatory adherence throughout the system lifecycle. Collaborate with cross-functional teams to enhanc...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$140K - $175K *

Empower your career by driving impactful relationships in government sectors. Manage a dedicated account portfolio, enhance customer satisfaction, and lead strategic engagement initiatives to maximize...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$70K - $100K *

Champion seamless customer experiences by resolving technical issues and collaborating cross-functionally. Leverage your expertise to enhance product reliability and drive customer satisfaction in a d...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$191K - $280K *

The Senior Director of the Access Experience Team will lead strategic initiatives for clients in the pharmaceutical and life sciences sectors, focusing on payer marketing and access strategies. This r...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Healthcare

$95K - $120K *

Unlock potential by delivering actionable insights through data analysis, visualization, and reporting. Collaborate across departments to enhance decision-making with automated dashboards and performa...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Join a team that's dedicated to enhancing equipment reliability through strategic leadership of preventive maintenance programs. Drive quality control, compliance, and continuous improvement while man...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$194K - $361K *

Reimagine your career by leading advanced analytics initiatives that drive enterprise performance. Collaborate across functions to translate insights into strategic actions, enhancing growth and marke...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$112K - $127K *

Elevate your career by supporting the design and maintenance of enterprise WAN infrastructure. Collaborate with diverse teams to ensure network reliability and performance across multiple locations, e...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $150K *

Join a team that's redefining HR support for a growing fellowship program. You'll oversee onboarding, advise managers, and enhance employee relations while ensuring a seamless experience for fellows a...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.