Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$125K - $150K *

Shape product strategy and execution for startup products by leveraging user insights, market analysis, and cross-functional collaboration to drive impactful recommendations and clear roadmaps for fou...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$130K - $160K *

Lead strategic banking initiatives by leveraging your enterprise sales expertise to build relationships and drive new business within Tier 1 global banks, shaping our go-to-market strategy and establi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$94K - $148K *

Join a team that's redefining technology sourcing strategies to drive savings and innovation. Lead cross-functional collaboration, manage supplier performance, and coach a talented team to optimize te...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Unlock potential by leading the SMB acquisition lifecycle, driving growth through innovative strategies and digital sales leadership. Collaborate with cross-functional teams to optimize customer engag...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$320K - $405K *

Design and oversee the electrical architecture for cutting-edge data centers, ensuring robust power distribution and integration of advanced technologies. Collaborate with partners to enhance prefabri...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$160K - $190K *

Accelerate progress at senior living communities by leading a high-performing Customer Success team, ensuring measurable outcomes and fostering strong partnerships to enhance care delivery and custome...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$175K - $210K *

Champion operational excellence in psychiatric care by leading a dynamic team focused on quality, compliance, and innovation. Drive improvements in provider operations and enhance mental healthcare de...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $180K *

Elevate your career by engaging with clients to design and implement innovative technical solutions. Leverage your expertise in APIs and customer collaboration to drive impactful results in a fast-pac...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$129K - $210K *

Transform issue management by leading a team to develop AI-assisted solutions, ensuring quality and accountability in remediation processes across GRC. Drive engineering excellence while fostering ind...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$250K - $300K *

Empower the future of AI in commerce media by leading strategy and execution across AI Labs and Data Science. Drive customer engagement, scale capabilities, and enhance product impact while building a...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$120K - $140K *

Lead the charge in managing a self-contained accounting division, driving performance across KPIs while fostering team growth and client relationships. This hands-on role requires expertise in invento...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Legal & Accounting

$110K - $130K *

Drive impactful solutions as a Forward Deployed Engineer, collaborating with clients to tackle complex challenges. Design and deploy AI-enabled applications, ensuring reliability and performance in re...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$172K - $238K *

Champion asset quality and model oversight in secured lending. Lead a team to monitor portfolio performance, ensure compliance, and mitigate risks across home equity and auto lending channels, driving...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$74K - $87K *

Transform client implementations by leading discovery, planning, and execution. Own project scope, timelines, and budgets to ensure successful adoption of solutions that align with business goals and...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Transform your career by leading a remote team of clinical auditors in Skilled Nursing Facility audits. Drive performance, ensure compliance, and enhance staff development while overseeing quality and...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$150K - $190K *

Accelerate user growth by leading cross-functional teams to optimize traffic acquisition strategies. Collaborate with marketing and engineering to drive impactful experiments and achieve business goal...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$80K - $95K *

Join a supportive team to enhance healthcare operations through HL7 interface monitoring, troubleshooting integration issues, and assisting with deployments in a remote environment, while ensuring sys...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$85K - $103K *

The Account Executive in-territory for Justworks in Dallas is responsible for managing the full sales cycle, from prospecting to closing deals, while building relationships within the small business c...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Business Services

$185K - $230K *

Advance your career by ensuring seamless performance of AI systems in diverse environments. Collaborate with customers and teams, automating and maintaining infrastructure for reliability across uncla...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Join a team that's redefining automation in industrial testing. You'll develop robust test frameworks and simulators, ensuring seamless integration and coverage for critical protocols while collaborat...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$182K - $226K *

Innovate with a dynamic team to solve customer challenges and drive growth. Leverage your technical expertise in pre-sales to enhance customer engagement and deliver impactful solutions in a fast-pace...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$188K - $276K *

Join a team that's redefining customer onboarding and compliance through innovative product management. Drive strategy, lead cross-functional teams, and enhance user experiences while ensuring top-tie...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Transportation

$320K - $405K *

Engineer cutting-edge protection and automation systems for high-voltage substations, ensuring reliable power distribution and integration across our infrastructure portfolio. Collaborate with teams t...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$71K - $90K *

Shape support operations by optimizing tools and processes, aligning teams, and driving initiatives that elevate the customer experience while ensuring efficient operations and effective reporting for...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Technical Services

$100K - $120K *

Unlock new business opportunities by driving sales in small specialty practices. Lead consultative sales cycles, build relationships, and deliver tailored solutions that enhance operational efficiency...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.