Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$125K - $150K *

Champion quality assurance for outsourced drug manufacturing, ensuring compliance and readiness for commercial launch. Lead a dynamic team, collaborating with cross-functional partners to build scalab...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$135K - $150K *

Drive excellence by executing full-scope IT audits, ensuring compliance with federal standards, and enhancing system security. Collaborate with stakeholders to assess controls and recommend improvemen...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Innovate and shape the future of water resources and dam safety as a senior engineer. Lead impactful projects, enhance client relations, and mentor emerging talent while collaborating with experts acr...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$85K - $90K *

Drive impactful analytics solutions by leading customer engagement workstreams, optimizing digital communications, and mentoring junior analysts. Leverage data to enhance government program performanc...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$84K - $115K *

Shape the future of employee financial wellbeing by leading retirement programs, ensuring compliance, and driving strategic initiatives that enhance retirement readiness and financial security for all...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Food & Beverages

$240K - $270K *

Join a team that's driving enterprise growth by owning relationships and closing deals. Leverage your expertise to navigate complex sales cycles, build a self-sourced pipeline, and expand accounts whi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$181K - $214K *

Lead the charge in defining and executing on-platform measurement strategies, ensuring effective ad performance tracking and reporting across diverse ad formats while collaborating with engineering an...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Technical Services

$125K - $150K *

Lead the charge in optimizing enrollment and fulfillment operations, ensuring timely service delivery and high-quality support for residents and Property Management Companies. Drive process improvemen...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$159K - $254K *

Drive impactful software development to enhance customer delivery experiences. Collaborate with cross-functional teams to design resilient systems that support real-time order tracking and efficient p...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Champion the commercial contracting process by drafting, reviewing, and negotiating agreements. Collaborate with cross-functional teams to streamline workflows and ensure compliance while supporting t...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $180K *

Transform clinical research practices by guiding study design and analysis. Collaborate with cross-functional teams to deliver key insights and evidence that drive product innovation in the healthcare...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $200K *

Unlock growth in Federal, Aerospace, and Defense sectors by managing strategic partnerships to enhance revenue and market presence. Collaborate across teams to drive pipeline and customer success with...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$125K - $150K *

Innovate AI-driven business applications by designing Python services and APIs that enhance data processing capabilities in both cloud and on-premises settings, ensuring robust performance and seamles...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Technical Services

$90K - $130K *

Drive business growth by executing strategic sales plans and building client relationships. Leverage industry tools to identify prospects, present solutions, and negotiate contracts while collaboratin...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$115K - $150K *

Join a team that's dedicated to guiding recovery efforts post-disaster. Lead a multi-disciplinary team, leveraging your expertise in FEMA programs to support local governments through complex recovery...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Business Services

$222K - $288K *

Transform innovation in healthcare as a strategic leader driving early-stage technology initiatives, translating clinical needs into viable product concepts, and orchestrating cross-functional collabo...

United StatesRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Healthcare

$100K - $140K *

Drive organizational success by partnering with field leaders to align workforce strategies, enhance talent development, and manage workplace resolutions, ensuring effective staffing and engagement ac...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Technical Services

$90K - $105K *

Accelerate audit excellence by managing financial and operational audits, ensuring efficiency and compliance while fostering continuous improvement and collaboration across teams to deliver high-quali...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$210K - $256K *

Transform the landscape of data management by leading a multi-year program that integrates governance, risk, and stakeholder alignment across diverse workstreams in a regulated banking environment, en...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Information Technology

$210K - $273K *

Drive the evolution of a robust online ML inference platform, enhancing model deployment, performance, and safety in high-traffic environments by collaborating with cross-functional teams and spearhea...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$165K - $195K *

Join a team that's redefining privacy governance by providing expert legal counsel on global privacy, cybersecurity, and AI matters. Collaborate with stakeholders to translate complex regulations into...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$120K - $230K *

Join a team that's driving growth by identifying and closing new business opportunities in consulting and AI-led transformation. Leverage your sales expertise to build strategic partnerships and accel...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Information Technology

$149K - $223K *

Unlock potential by leading enterprise AI solutions, bridging sales and technical teams to deliver impactful transformations. Engage with customers to architect scalable solutions, ensuring operationa...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Consumer Technology

$75K - $90K *

Elevate your career by managing diverse renovation projects from inception to completion. Oversee planning, budgeting, and client communication while ensuring quality and timely delivery in a dynamic...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$100K - $120K *

Grow client relationships by managing and expanding large renewal accounts. Collaborate with cross-functional teams to drive revenue retention while maximizing client satisfaction and implementing str...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.