Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$112K *

Take ownership of premium flight operations as a First Officer, delivering exceptional service and safety while fostering career growth through advanced training and leadership opportunities within a...

United StatesRemote

Reposted 1 week ago

  •   15+ years exp.  •   Transportation

$84K - $100K *

Drive the growth of B2B programmatic practices, overseeing campaign operations, client relationships, and strategy development while ensuring campaign excellence across multiple platforms and stakehol...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Business Services

$93K - $120K *

Transform the leave of absence experience by overseeing compliance, managing vendor relationships, and implementing strategic improvements. Collaborate with HR and leadership to ensure seamless proces...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$78K - $103K *

Join a dynamic team to perform complex coding reviews in Radiation Oncology. Leverage your expertise in CPT, HCPCS, and ICD-10 to resolve errors and ensure accurate billing. This remote role offers a...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$73K - $102K *

Advance your career by leading full-stack Java development projects, leveraging cloud technologies and DevOps practices to deliver innovative solutions. Collaborate with cross-functional teams to driv...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$173K - $255K *

Drive innovation in AI systems by designing and building scalable backend solutions, ensuring security and governance while enhancing developer productivity and operational health across diverse workl...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$95K - $115K *

Drive customer success by building strong relationships with enterprise accounts, ensuring strategic guidance, adoption, and retention. Collaborate cross-functionally to enhance customer experiences a...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$125K - $190K *

Lead the regional People strategy, partnering with executives to drive workforce planning, talent management, and organizational effectiveness while ensuring consistent execution of People programs ac...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Technical Services

$130K - $150K *

Shape the future of healthcare quality assurance by leading a dynamic team focused on DRG validation. Drive training, audits, and process improvements to enhance clinical accuracy and operational effi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$184K - $230K *

Lead the Complex Systems portfolio to enhance climate impact, ensuring cohesive strategy and program effectiveness across Land, Transportation, and Industry while aligning resources for sustainable so...

United StatesRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Energy & Utilities

$80K - $95K *

Join a team that's dedicated to enhancing housing standards through comprehensive inspections and evaluations of federally subsidized properties, ensuring compliance with safety regulations and improv...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Transportation

$120K - $145K *

Empower your career as a Senior Electrical Engineer, leading cutting-edge designs for high-capacity data centers, while collaborating with top industry professionals on impactful, mission-critical pro...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$138K - $190K *

Advance solutions in behavioral health by leveraging technical expertise to drive sales success. Collaborate with teams to deliver tailored demonstrations, support RFPs, and align strategies with clie...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Grow your career with a dynamic sales role focused on driving growth in industrial manufacturing. Engage with customers, manage the sales process, and achieve targets while building lasting relationsh...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$145K - $175K *

Lead the charge in architecting scalable Azure solutions across multi-team programs, aligning client goals with innovative designs. Mentor teams, drive modernization efforts, and ensure high-quality d...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Energy & Utilities

$120K - $140K *

Engineer key aspects of a native iOS app, enhancing user experiences and maintaining robust code. Collaborate cross-functionally to drive performance, scalability, and code quality while iterating on...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Media

$90K - $130K *

Drive exceptional client experiences by leading client services strategy and operations across screening services. Empower teams to deliver timely, accurate support while fostering a culture of accoun...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$95K - $115K *

Unlock potential by driving impactful marketing strategies for a key partnership. Collaborate across teams to create campaigns, manage events, and analyze performance, directly influencing revenue gro...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$170K - $210K *

Join a dynamic team to develop transformative brand strategies that inspire clients and drive impactful campaigns. Collaborate across functions to deliver insights and solutions that elevate brand per...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $180K *

Join a team that's redefining client success in the pharma sector by leading strategic initiatives, fostering senior-level relationships, and driving innovative marketing solutions for key accounts wh...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Healthcare

$163K - $237K *

Lead the charge in shaping advertising agreements for a dynamic legal team. Collaborate across functions to drive growth in our ad tech initiatives while ensuring compliance and efficiency in a fast-p...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$75K - $90K *

Unlock potential by providing compassionate, holistic care as you assess, plan, and coordinate patient needs in a dynamic hospice environment, ensuring quality support for patients and families throug...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$131K - $240K *

Shape the future of training and development in orthopedic medical devices, enhancing sales effectiveness and fostering strong partnerships across teams. Drive learning initiatives and support surgica...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Healthcare

$201K - $251K *

Engage with Key Opinion Leaders to drive strategic marketing initiatives, leveraging clinical expertise to influence oncologists and enhance brand strategy. Collaborate cross-functionally to execute i...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Lead comprehensive evaluations of federally subsidized housing, ensuring compliance with safety and accessibility standards. Collaborate with inspectors to enhance operational performance and resolve...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Transportation

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.