Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$134K - $185K *

Shape the future of manufacturing by leading electricity and automation initiatives. Oversee process control and MES strategies to enhance operational performance and compliance while managing a skill...

1 week ago

  •   8 - 10 years exp.  •   Food & Beverages

$125K - $150K *

Join a team that's driving digital transformation by spearheading sales in Application Modernization Services, leveraging AI trends to cultivate strategic client relationships and optimize business gr...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Technical Services

$131K - $228K *

Empower innovation by developing and optimizing radar perception systems for autonomous agricultural technology. Collaborate across hardware and software to enhance sensor fusion and ensure robust per...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$88K - $128K *

Drive impactful actuarial analyses and modeling to enhance healthcare services, collaborating with teams to ensure accurate financial forecasting and decision support that shapes health program strate...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Transform project delivery by leading complex, multi-phase initiatives, ensuring timely completion within budget and quality standards. Collaborate with cross-functional teams and maintain accountabil...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$144K - $184K *

Transform strategic accounts by driving sales and fostering executive relationships. Leverage deep industry knowledge to identify opportunities and enhance client satisfaction, ensuring growth and ret...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$116K - $150K *

Champion innovative SAP FICA solutions, guiding clients through implementation and configuration while ensuring alignment with business needs and budgetary constraints. Drive value-added consulting to...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Information Technology

$110K - $130K *

Transform the quality landscape of data center equipment by overseeing supplier audits, inspections, and continuous improvement initiatives. Collaborate with cross-functional teams to ensure complianc...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$80K - $95K *

Transform sales operations by leading deal desk activities, guiding reps on deal structuring, and driving data analysis for revenue forecasting. Collaborate with finance and sales leadership to ensure...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Lead the charge in enhancing patient care by overseeing a dedicated rehabilitation team, managing operations, and ensuring compliance while fostering professional growth and community outreach...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$72K - $121K *

Shape the future of talent acquisition by managing full-cycle recruiting, collaborating with hiring managers, and enhancing candidate experiences while ensuring organized processes and timely communic...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$180K - $200K *

Join us as a Principal Architect to drive technical innovation and unify systems across platforms. Collaborate with teams to design cloud-based solutions, mentor engineers, and enhance product deliver...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$136K - $160K *

Empower healthcare partnerships by leading a regional team to enhance strategic relationships, drive business growth, and ensure exceptional service delivery in nutrition support across diverse health...

Ankeny, IARemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$136K - $160K *

Drive productivity and success by leading a field team to foster healthcare partnerships, ensure performance excellence, and implement effective sales strategies in a dynamic environment that promotes...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Elevate enterprise AI initiatives by partnering with clients to drive strategic solutions. Leverage your expertise to engage senior leaders, design impactful demos, and accelerate deal cycles, ensurin...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$127K - $157K *

Champion medical affairs for Photofrin and PDT, engaging with healthcare professionals and leading initiatives. This role offers autonomy and visibility, ideal for experienced Medical Affairs professi...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Unlock potential by building and deploying AI systems across diverse businesses. Collaborate with CEOs to identify needs, create prototypes, and drive growth through innovative solutions while managin...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$138K - $180K *

Lead the delivery of complex DevOps and cloud infrastructure projects, driving collaboration across engineering teams. Manage risks, dependencies, and execution plans to ensure successful project outc...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$222K - $288K *

Advance your career by leading global infrastructure strategy and operations. Drive modernization across cloud, networking, and security while ensuring compliance and scalability for 24/7 clinical and...

United StatesRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Healthcare

$90K - $180K *

Drive market expansion and adoption of innovative medical devices by developing strategic relationships and sales initiatives to increase market share within healthcare systems, focusing on cardiologi...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$90K *

Tackle complex sales challenges by driving revenue growth through strategic account management and new business development. Collaborate with internal teams to deliver exceptional client service and l...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Lead on-site coordination for multifamily renovation projects, ensuring compliance with plans and safety standards. Oversee subcontractors, manage schedules, and maintain quality control to deliver pr...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$80K - $90K *

Transform business needs into actionable requirements by bridging technical solutions and operational workflows. Collaborate across teams to enhance product creation technology systems, ensuring seaml...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$115K - $168K *

Engineer innovative web interfaces as part of a dynamic team, enhancing underwriting workflows. Collaborate across disciplines to deliver a user-centric platform that scales, integrating AI for effici...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$125K - $150K *

Deliver scalable backend services and APIs for scholarly content, enhancing search and discovery systems. Collaborate with cross-functional teams to optimize performance and reliability while integrat...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.