Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$79K - $108K *

Join a team that's transforming technology into opportunity by administering and governing Microsoft Power Platform environments. Leverage your expertise to enhance mission-critical projects and drive...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$97K - $115K *

Transform technology into opportunity by developing innovative SharePoint solutions. Lead the charge in enhancing user experiences and integrating Microsoft 365 services while collaborating with cross...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$85K - $92K *

Lead the charge in managing Safety and Compliance Committee operations, ensuring accurate records, effective onboarding, and seamless collaboration with stakeholders to uphold governance standards and...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$102K - $138K *

Lead major incident management efforts to enhance healthcare IT operations, ensuring stability and availability of critical systems. Collaborate with cross-functional teams to resolve high-severity in...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$129K - $149K *

Unlock your potential as you collaborate with teams to design and optimize cloud solutions, ensuring secure and cost-efficient operations for mission-critical projects. Drive innovation and efficiency...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$153K - $207K *

Lead the design and optimization of advanced network security architectures, focusing on Palo Alto Networks solutions. Provide senior technical leadership, drive enterprise-scale implementations, and...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$131K - $178K *

Develop and support scalable microservices for enterprise systems, collaborating with product and engineering teams to ensure high-quality delivery within a cloud-native platform, while mentoring and...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Information Technology

$131K - $178K *

Join a team that's driving identity data management initiatives, ensuring accurate aggregation and synchronization of identity and entitlement data across diverse environments. Lead project delivery a...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $143K *

Elevate your career by driving loyalty solutions sales within the financial services sector. Leverage your expertise to build relationships, execute strategies, and secure multimillion-dollar deals wh...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$320K - $488K *

Optimize the end-to-end software architecture for high-performance rack-scale solutions, collaborating with teams and customers to ensure product alignment and execution. Drive innovation while mentor...

RemoteRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$128K - $226K *

Unlock potential by leading the delivery of APIs and integrations that enhance healthcare tools. Collaborate with engineering teams to ensure reliable, user-friendly solutions that drive business grow...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$179K - $341K *

Elevate enterprise outcomes by bridging AI capabilities with client needs. In this hands-on role, you'll design solutions, lead workshops, and serve as a trusted advisor while prototyping and guiding...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Information Technology

$159K - $286K *

Drive transformative growth by managing key accounts, cultivating executive relationships, and delivering tailored solutions. Leverage industry expertise to enhance customer satisfaction and ensure pr...

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Lead the charge in implementing EHS programs, ensuring compliance with regulations, and fostering a culture of safety and environmental stewardship across all levels of the organization...

1 week ago

  •   5 - 7 years exp.  •   Food & Beverages

$179K - $232K *

Shape the future of technology architecture by leading complex initiatives, aligning enterprise strategies, and driving innovation across multiple domains to enhance operational efficiency and busines...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Transportation

$135K - $150K *

Lead the charge in enhancing cybersecurity operations by managing incident response, mentoring SOC analysts, and developing processes to effectively identify and mitigate threats in a 24/7 Security Op...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $160K *

Create impactful data solutions by leading a cross-functional team in managing high-priority IT projects for federal clients. Drive collaboration and ensure project success through effective communica...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$218K - $284K *

Empower decision-making by leading enterprise AI strategy, transforming innovative concepts into scalable applications that drive measurable business outcomes across diverse operational areas and enha...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $220K *

Drive sales excellence by leading a regional team in the Urology and Incontinence sector. Foster strategic partnerships, enhance market presence, and achieve revenue growth through effective coaching...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$119K - $186K *

Lead the charge in driving complex pre-sales engagements and shaping value-based solutions for customers. Collaborate with cross-functional teams to deliver impactful presentations and mentor peers, e...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Drive impactful oncology reimbursement strategies through hybrid engagement, balancing virtual support with essential in-field interactions across healthcare providers to enhance access to critical th...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Accelerate progress at the forefront of veterinary sales by driving new business, building relationships, and leveraging innovative solutions to enhance veterinary practices and customer loyalty in a...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$140K - $180K *

Partner with us to drive business development initiatives in the water treatment sector, fostering client relationships and solutions. Collaborate with leadership and teams, navigating client needs an...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$175K - $250K *

Champion strategic growth by leading market development, enhancing client relations, and uniting teams for impactful solutions. Leverage technical expertise to unlock opportunities and drive success i...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$100K - $175K *

Transform your career as a Senior Software Engineer, leading cross-functional teams to design and implement Java Spring Boot microservices and RESTful APIs on AWS, driving innovation and operational e...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.