Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$113K - $188K *

Shape the future of data governance by leading teams to implement actionable AI programs, managing client relationships, and ensuring alignment across business and technical stakeholders for sustainab...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Business Services

$89K - $148K *

Optimize clinical documentation integrity operations by leading a dedicated team, ensuring compliance with best practices, and enhancing performance metrics to support effective healthcare delivery an...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$113K - $188K *

Optimize program execution by leading Integrated Master Scheduling (IMS) for Department of War initiatives. Collaborate with stakeholders to enhance visibility, manage risks, and support decision-maki...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$98K - $163K *

Analyze and maintain program data to enhance recruitment and onboarding processes. Collaborate with stakeholders to ensure accurate reporting and insights that drive decision-making and improve partic...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$89K - $148K *

Lead the charge in enhancing financial operations by delivering advanced analysis, ensuring compliance, and supporting internal controls for federal financial systems, contributing to a high-performin...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$90K - $145K *

Drive the development and management of third-party vendor relationships, ensuring effective communication, oversight, and resource allocation within the Vendor Management team to meet corporate objec...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$130K - $165K *

Oversee full lifecycle of U.S. government programs, managing stakeholders and technical details to ensure timely delivery and compliance. Forge trust with clients while leading multiple complex projec...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Energy & Utilities

$141K - $166K *

Lead the charge in shaping product messaging and go-to-market strategies, driving awareness and adoption through cross-functional collaboration and strategic insights. This role demands a proactive in...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$124K - $207K *

Drive impactful analytics in Medical Affairs by developing KPIs, analyzing data trends, and collaborating with cross-functional teams to enhance decision-making and resource allocation for optimal bus...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$90K - $180K *

Lead a team in maintaining facilities across a regional area, ensuring efficient operations and compliance with safety standards. Collaborate with store management and vendors while driving continuous...

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$68K - $131K *

Join our team to develop cutting-edge digital hardware for high-performance avionics systems. You'll engage in product lifecycle management, troubleshooting, and cost-saving initiatives, directly impa...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$175K - $195K *

Shape the future of global HR operations by enhancing systems and processes for a seamless employee lifecycle. Collaborate cross-functionally to improve workflows, compliance, and service effectivenes...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$88K - $105K *

Join a dynamic team to lead audits and appeals, optimizing reimbursement and compliance. Drive strategic initiatives, manage a multidisciplinary team, and collaborate across departments to enhance rev...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$135K - $187K *

Grow your career with a dynamic team focused on crafting scalable software solutions. Collaborate cross-functionally to design impactful APIs and lead innovations that drive efficiency and elevate cus...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$156K - $234K *

Drive the evolution of Sales Operations into an AI-driven powerhouse by architecting innovative AI solutions, redesigning processes, and establishing best practices that enhance efficiency and perform...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$500K+*

IntelliRad Imaging, LLC is seeking a Remote Diagnostic Radiologist to join their physician-owned group, working evening shifts from 8 PM to 4 AM EST. The role involves interpreting general radiology s...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$116K - $166K *

Grow your career by engaging healthcare providers through innovative outreach strategies. Collaborate with cross-functional teams to enhance patient care and drive business objectives in a dynamic, cu...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$116K - $166K *

Shape healthcare engagement by leveraging digital tools and in-person outreach to enhance provider relationships and patient care. Collaborate across teams to deliver insights and strategies that impr...

Cedar Rapids, IARemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$94K - $266K *

Transform your career by driving software sales growth through strategic client engagement, managing the full sales cycle, and collaborating across teams to deliver impactful solutions that meet clien...

1 week ago

  •   5 - 7 years exp.  •   Business Services

$132K - $271K *

Unlock potential by leading pre-sales efforts for complex software solutions. Collaborate with clients and partners to deliver tailored demonstrations, support RFPs, and develop reusable assets that d...

1 week ago

  •   8 - 10 years exp.  •   Business Services

$84K - $135K *

Grow your career by delivering tailored energy solutions to commercial clients. Utilize your sales expertise in the deregulated market while cultivating long-term partnerships and engaging with divers...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$90K - $150K *

Shape the future of cybersecurity by identifying vulnerabilities in blockchain smart contracts. Collaborate on security audits, enhance tools, and embrace emerging technologies to bolster security sol...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$87K - $293K *

Join a team that's transforming the banking industry through strategic digital solutions. Lead client engagements, harness AI and data to solve complex business challenges, and drive operational effic...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Business Services

$80K - $95K *

Take ownership of complex projects, managing detailing teams and vendor relations. Ensure efficient operations from estimation to completion while fostering customer satisfaction and profitability in...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$88K - $105K *

Lead the charge in engineering project excellence, guiding teams to deliver top-quality outcomes and fostering innovation while mentoring future leaders in the field...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Technical Services

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.