Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$125K - $145K *

Unlock potential by leading complex multi-disciplinary projects to achieve client goals, overseeing contracting, risk management, and deliverable production, while supporting program growth and commun...

RemoteRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Technical Services

$150K - $180K *

Champion the future of revenue operations by leading GTM infrastructure, analytics, and team scaling across multiple verticals. Drive strategic initiatives to enhance efficiency and revenue growth in...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $90K *

Take ownership of day-to-day campaign execution for paid search and affiliate marketing channels while driving performance optimizations and ensuring data integrity across multiple retail brands in a...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$88K - $95K *

Elevate healthcare access by providing clinical support and driving sales growth across government accounts. Collaborate with VA and DoD partners to expand Cochlear's hearing solutions in the Ohio/Ind...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$115K - $140K *

Join a team that's dedicated to transforming patient engagement through innovative marketing strategies. You'll develop and execute multichannel campaigns, crafting compelling content that drives enro...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Healthcare

$85K - $100K *

Support the oncology care journey by delivering high-quality virtual patient care, coordinating services, and providing clinical support while building strong relationships with patients and clinical...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Healthcare

$295K - $312K *

Join a team that's shaping the future of drug safety! Provide operational leadership across pharmacovigilance functions, oversee compliance and vendor relationships, and ensure high-quality safety rep...

United StatesRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Transform application deployment by collaborating with teams to streamline processes, enhance automation, and ensure high-quality releases across environments while mentoring junior members and drivin...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$156K - $275K *

Lead the charge in shaping the technical strategy for reliability and infrastructure. Drive initiatives across teams, design scalable systems, and enhance operational excellence while mentoring engine...

United StatesRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$125K - $150K *

Unlock potential by leading strategic initiatives for a portfolio of Department of War customers. Drive growth, foster executive relationships, and ensure impactful operational outcomes while guiding...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$90K - $120K *

Transform customer experiences by leading a dynamic Policy Operations team, driving process innovation, and collaborating with cross-functional partners to enhance service delivery and operational eff...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$95K - $115K *

Join a fast-paced team to drive key operational initiatives, optimize execution, and enhance cross-functional collaboration, all while delivering impactful, executive-ready communications in a dynamic...

Reposted 6 days ago

  •   Less than 5 years exp.  •   Business Services

$255K - $295K *

Lead the technical direction for foundational services, guiding architecture and execution across teams to enhance platform capabilities for customer and partner experiences. Mentor engineers and infl...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Explore new business opportunities and build lasting client relationships. Drive the full sales cycle, from prospecting to closing, while collaborating with cross-functional teams to deliver tailored...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Business Services

$73K - $115K *

Launch your engineering career by tackling real manufacturing challenges. Engage in a three-year rotational program that fosters growth through mentorship, diverse experiences, and exposure to industr...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Business Services

$90K - $110K *

Lead the charge in resolving complex technical issues, enhancing support processes, and collaborating with engineering teams to improve product functionality and customer satisfaction in a dynamic B2B...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Information Technology

$235K - $270K *

Unlock potential by leading actuarial strategy and health economic analyses. Collaborate with cross-functional teams to enhance value propositions and drive commercial growth while translating complex...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Healthcare

$200K - $225K *

Transform healthcare data into actionable insights by leading actuarial strategy and health economic analyses. Collaborate with cross-functional teams to enhance value propositions and drive commercia...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$162K - $203K *

Drive impactful market research initiatives by collaborating with cross-functional teams to translate business needs into actionable insights, ensuring high-quality execution and strategic decision-ma...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Elevate product design by leading innovative initiatives, guiding cross-functional teams, and shaping user experiences from concept to delivery. Drive design excellence and foster a culture of feedbac...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Lead and scale a high-performing global SDR team, optimizing outbound strategies and driving pipeline through innovative coaching and performance tracking in a dynamic, fast-paced environment...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$180K - $225K *

Transform the future of auto claims by designing AI agents that enhance decision-making and streamline processes. Join a dynamic team to build innovative solutions that improve efficiency and accuracy...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Business Services

$77K - $104K *

Lead transformative knowledge strategies that enhance customer experiences and drive AI integration across multiple functions. Collaborate with teams to ensure knowledge is accurate, discoverable, and...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $140K *

Lead the charge in delivering innovative healthcare solutions by engaging with clients, understanding their needs, and providing technical guidance throughout the sales process to drive successful out...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $125K *

Join a team that's redefining programmatic strategy and activation. Lead the expansion of service offerings, collaborate cross-functionally, and drive impactful digital advertising initiatives while m...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.