Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$180K - $220K *

Lead the infrastructure engineering team to drive strategic initiatives, enhance developer productivity, and ensure reliability as the organization scales towards ambitious growth targets, including A...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Information Technology

$180K - $225K *

Transform the future of auto claims by designing AI agents that enhance decision-making and streamline processes. Join a dynamic team to build innovative solutions that improve efficiency and accuracy...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Business Services

$77K - $104K *

Lead transformative knowledge strategies that enhance customer experiences and drive AI integration across multiple functions. Collaborate with teams to ensure knowledge is accurate, discoverable, and...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $140K *

Lead the charge in delivering innovative healthcare solutions by engaging with clients, understanding their needs, and providing technical guidance throughout the sales process to drive successful out...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $125K *

Join a team that's redefining programmatic strategy and activation. Lead the expansion of service offerings, collaborate cross-functionally, and drive impactful digital advertising initiatives while m...

RemoteRemote

5 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $145K *

Engage with cross-functional teams to drive AI security product marketing initiatives, focusing on buyer insights, competitive analysis, and effective sales enablement. Collaborate on launches and con...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Information Technology

$145K - $185K *

Join a dynamic team to drive innovation in HELOC underwriting, enhancing efficiency and borrower experience. Collaborate cross-functionally to streamline processes, leverage AI, and lead product strat...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$135K - $145K *

Lead the charge in strategic account management, driving growth and strengthening customer partnerships. Collaborate cross-functionally to align business objectives with customer needs while overseein...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$157K - $192K *

Develop and enhance a cloud-native agent harness, ensuring secure, reliable, and efficient operations. Collaborate with a dynamic team to deliver features, fix bugs, and innovate using AI throughout t...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$94K - $117K *

Unlock your potential as a key underwriter, evaluating complex insurance applications and guiding risk assessment. Collaborate with a dynamic team to enhance underwriting practices while fostering rel...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$111K - $197K *

Champion integration solutions by leading projects, conducting discovery sessions, and implementing complex integrations for clients in Higher Education and Nonprofit sectors. Drive results and ensure...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Consumer Technology

$125K - $150K *

Accelerate growth by leading commercial strategy and sales for Mid-Market & SMB segments. Drive revenue, manage KPIs, and collaborate cross-functionally to enhance client satisfaction and market prese...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$130K - $160K *

Deliver high-quality telemedicine care to complex patients, focusing on symptom management and improving outcomes. Collaborate with a multidisciplinary team to enhance patient experiences and facilita...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$88K - $105K *

Empower cross-functional teams to achieve project goals by leading planning, execution, and delivery. Utilize technical skills and strategic influence to manage risks and ensure alignment with long-te...

Reposted 5 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$135K - $160K *

Champion innovation in AI engineering by building intelligent systems that enhance productivity and streamline workflows, enabling teams to deliver exceptional user experiences and drive the future of...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Consumer Technology

$140K - $160K *

Design and enhance intelligent AI systems for K-12 assessment, collaborating across disciplines to create reliable, evaluative solutions that integrate seamlessly into educational frameworks and suppo...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$123K - $155K *

Lead the charge in enhancing incident management practices across global data centers. Collaborate with teams to develop standards, improve processes, and drive operational excellence, ensuring effect...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$270K - $340K *

Unlock potential by driving sales for innovative healthcare compliance solutions. Own the full sales cycle with health plans, transforming initial conversations into lasting partnerships while shaping...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Manage the full sales cycle for mid-sized jurisdictions, focusing on pipeline growth and relationship building. Drive revenue through prospecting, closing deals, and collaborating with cross-functiona...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Consumer Technology

$229K - $330K *

Join us to redefine revenue operations by leading a dynamic team that transforms GTM strategies into actionable insights, ensuring scalable success across diverse market segments and driving AI-enhanc...

United StatesRemote

5 days ago

  •   11 - 15 years exp.  •   Information Technology

$100K - $115K *

Engineer innovative Salesforce solutions and integrations, enhancing business applications and operational efficiency. Collaborate with cross-functional teams to deliver secure, scalable technology th...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$120K - $145K *

Accelerate progress at customer deployments and adoption, driving value realization across a portfolio of accounts. Leverage technical fluency and business acumen to ensure successful outcomes and dee...

RemoteRemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$67K - $101K *

Lead the charge in developing and executing validation plans for engine systems. Collaborate with cross-functional teams to analyze performance data and drive technical solutions, ensuring reliability...

5 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$157K - $183K *

Unlock innovative Finance and Accounting outsourcing solutions by leading design and development efforts. Collaborate with cross-functional teams to optimize service delivery and drive strategic clien...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Business Services

$150K - $200K *

Join us in a pivotal leadership role to enhance customer success initiatives, drive operational excellence, and build a high-performing team focused on customer engagement and retention strategies in...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.