Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$68K - $131K *

Join a dynamic team of engineers to design and develop innovative flight management software for military applications, enhancing operational capabilities in a collaborative AGILE environment...

5 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$150K - $180K *

Join a dynamic team to drive channel sales and co-sell strategies with leading AI partners. Leverage your expertise to build relationships, identify opportunities, and lead teams to close deals, all w...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Information Technology

$65K - $100K *

Drive operational excellence by leading teams, enhancing customer service, and optimizing financial performance. Foster a collaborative environment while implementing business solutions and ensuring c...

5 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$110K - $130K *

Execute go-to-market strategies for product releases, translating technical features into compelling narratives. Collaborate with cross-functional teams to enhance customer engagement and maintain hig...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Information Technology

$150K - $170K *

Transform business growth by developing strategic partnerships and driving sales in IT infrastructure. Leverage your expertise to build relationships, conduct market analysis, and exceed revenue targe...

RemoteRemote

5 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$90K - $105K *

Elevate your career by managing the operational lifecycle of B2G products. Drive onboarding, renewals, and readiness activities while ensuring smooth day-to-day operations. Collaborate cross-functiona...

Iowa City, IARemote

5 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$160K - $200K *

Accelerate revenue growth by engaging Managed Service Providers, leading the full sales cycle, and building strong partnerships to drive NodeZero adoption and deliver compelling business solutions in...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Join a team that's dedicated to enhancing coding accuracy through comprehensive audits and educational support. Leverage your expertise in ICD-10, CPT, and HCPCS coding to drive compliance and improve...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$250K - $350K *

Transform your career by leading underwriting strategy and oversight. Supervise managers, enforce guidelines, and drive quality across all programs, ensuring a robust underwriting framework and risk m...

United StatesRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$80K - $95K *

Support and oversee a multidisciplinary rehab team, ensuring effective clinical programs and compliance while fostering collaboration and quality care in a skilled nursing facility setting...

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Drive the design and execution of large-scale data centers, managing complex projects from initiation to construction. Oversee integrated schedules and governance, ensuring accountability while enabli...

RemoteRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$90K - $105K *

Elevate strategic communications for vaccine development, translating complex science into engaging narratives for diverse audiences while managing multiple priorities in a dynamic global health envir...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$146K - $152K *

Collaborate with a multidisciplinary team to provide exceptional orthopedic care, supporting surgeries and patient management at a leading trauma center, while ensuring optimal outcomes and fostering...

Reposted 5 days ago

  •   Less than 5 years exp.  •   Healthcare

$175K - $250K *

Transform the GTM landscape by leading strategic initiatives, aligning teams, and driving measurable outcomes across solution areas. Foster collaboration and innovation to enhance sales processes and...

United StatesRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Information Technology

$125K - $150K *

Join a team that's shaping the future of machine learning by leveraging traditional algorithms and financial data. Collaborate with clients to design, build, and optimize innovative solutions while ad...

Des Moines, IARemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Information Technology

$125K - $150K *

Elevate your career by leading strategic initiatives in enterprise systems. Drive operational excellence, enhance data integration, and champion modern processes to support institutional priorities an...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$153K - $171K *

Join a dynamic team to orchestrate complex technical programs, driving alignment and clarity across product and engineering. Empower teams to deliver impactful outcomes while leveraging AI insights fo...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Technical Services

$110K - $130K *

Unlock potential by leading operational excellence across Engineering teams, ensuring timely delivery and adherence to standards. Collaborate with cross-functional teams to drive accountability and en...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Shape the future of cybersecurity in higher education by delivering expert assessments, advisory services, and tailored remediation plans that empower institutions to enhance their security posture an...

United StatesRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$115K - $135K *

Lead the charge in developing high-quality software solutions, mentoring engineers, and driving process improvements. Collaborate with stakeholders to enhance systems and deliver impactful results in...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$200K - $250K *

Join us in shaping technical strategies and growth initiatives for federal opportunities. Collaborate across teams to develop compelling solutions that drive success in complex pursuits, ensuring alig...

United StatesRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$105K - $110K *

Drive innovation as a Software Engineer III, enhancing full-stack capabilities and mentoring junior developers while collaborating with stakeholders to improve engineering processes and deliver impact...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Join a dynamic team as a Strategic Sales Engineer, driving sales growth through technical expertise and collaboration. Engage with sales leadership to create opportunities and deliver solutions across...

United StatesRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$70K - $205K *

Innovate digital laboratory operations by delivering strategic solutions that enhance scientific intelligence and user experiences, while collaborating with clients to transform their data-driven envi...

5 days ago

  •   Less than 5 years exp.  •   Business Services

$79K - $98K *

Drive statewide mine safety training initiatives by delivering MSHA courses, developing safety programs, and providing compliance support to operators. Engage with community colleges and industry part...

5 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.