Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$80K - $95K *

Unlock potential by configuring and supporting LIMS/ELN systems, ensuring seamless operations and compliance. Collaborate with teams to gather requirements, troubleshoot issues, and enhance workflows...

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$136K - $170K *

Transform patient access by leading reimbursement initiatives and collaborating with cross-functional teams to maximize the reach of innovative healthcare technologies while ensuring compliance and ed...

RemoteRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Healthcare

$88K - $102K *

Elevate your career by managing day-to-day financial operations, ensuring compliance, and supporting strategic financial initiatives. Collaborate with diverse teams to maintain financial health and dr...

United StatesRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$85K - $95K *

Drive the end-to-end delivery of complex curriculum projects, collaborating across teams to ensure high-quality outcomes that meet business and learner needs while managing risks and stakeholder expec...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$90K - $130K *

Drive strategic partnerships by leading the sales cycle for hospital systems. Engage C-suite executives to negotiate complex agreements, enhancing operational efficiency and revenue retention in wound...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$176K - $281K *

Empower your career by leading complex service portfolios, driving strategic initiatives, and delivering measurable value through innovative solutions in a dynamic environment. Collaborate across team...

RemoteRemote

4 days ago

  •   8 - 10 years exp.  •   Telecommunications & Hardware

$73K - $132K *

Grow your career with a dynamic team solving complex challenges in electric transmission design for high-voltage systems, ensuring compliance with industry standards and delivering impactful projects...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Technical Services

$100K - $155K *

Join a dynamic team to lead the deployment and support of cloud security solutions, ensuring optimal performance and customer satisfaction through expert technical guidance and strategic partnerships...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$117K - $176K *

Drive the development and governance of enterprise processes, ensuring alignment across operations and technology. Lead initiatives that enhance operational excellence and foster adoption of standardi...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$116K - $189K *

Transform partner marketing strategies by developing data-driven co-marketing plans, driving pipeline growth, and aligning sales teams with partners. Collaborate to create impactful campaigns and mana...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Transportation

$110K - $130K *

Accelerate progress at the forefront of digital transformation by managing complex data solutions. Collaborate with a global IT team to innovate and optimize SAP BW and BPC applications, driving effic...

RemoteRemote

4 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$165K - $195K *

Join us to define and drive the product vision for Retail Experiences, enhancing guest journeys through innovative digital solutions. Collaborate across teams to create impactful, user-centric product...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$80K - $95K *

Take ownership of the Colleague Accounts Receivable solutions, collaborating with higher education clients to design, implement, and optimize systems while ensuring effective billing, payment processi...

United StatesRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Empower institutions by delivering tailored ERP solutions in financial aid, optimizing processes, and ensuring compliance. Collaborate with stakeholders to enhance student services and drive strategic...

United StatesRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$95K - $115K *

Drive the success of a dynamic claims team by leading, coaching, and optimizing performance. Ensure quality outcomes, manage client relationships, and execute strategic initiatives for continuous impr...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$80K - $95K *

Transform the claims process by leading a team of adjusters, ensuring quality and efficiency while managing complex cases. Drive performance through coaching, feedback, and strategic oversight to meet...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$155K - $241K *

Join us to shape the future of platform engineering by driving strategic initiatives, influencing organizational architecture, and enhancing developer experience across a multi-cloud environment. Your...

United StatesRemote

Reposted 4 days ago

  •   11 - 15 years exp.  •   Information Technology

$300K *

Unlock potential by leading national consultant relations, driving strategy, and managing a team to enhance employer opportunities. Engage with key consulting firms while fostering relationships that...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $155K *

Lead content operations for a federal web services program, managing a team to ensure timely, accurate, and accessible communication. Drive strategic planning, oversee Drupal content management, and e...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$90K - $110K *

Champion growth by expanding dealership networks and driving financing adoption in the powersports industry. Build relationships, identify opportunities, and enhance dealer experiences through strateg...

RemoteRemote

4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$130K - $155K *

Transform data into actionable insights by leading research initiatives, collaborating with business leaders, and developing predictive models to drive strategic decisions and enhance product offering...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$125K - $150K *

Drive AI transformations in manufacturing by collaborating with C-level executives to identify high-impact opportunities, build tailored solutions, and achieve measurable results in core operating pro...

United StatesRemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$95K - $165K *

Lead the charge in optimizing bulk distribution services, managing barge supply chains, and ensuring operational excellence from stockpile management to delivery. Collaborate cross-functionally to enh...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$125K - $150K *

Empower customer success by designing impactful journeys that drive retention and revenue. Lead cross-functional teams to create and optimize service blueprints, ensuring seamless customer experiences...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Information Technology

$190K - $283K *

Drive impactful data analyses and innovative experiment design to enhance product strategies and optimize Ads Marketplace performance, collaborating with cross-functional teams in a flexible, hybrid w...

United StatesRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Consumer Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.