Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$134K - $241K *

Champion trade compliance by leading a team to ensure adherence to regulations, manage risks, and implement strategies that align with business goals while fostering a culture of integrity and innovat...

United StatesRemote

4 days ago

  •   11 - 15 years exp.  •   Real Estate & Construction

$78K - $140K *

Lead national account growth and category expansion in the Heavy-Duty sector. Drive strategic initiatives, build customer relationships, and collaborate across functions to enhance profitability and m...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Transportation

$66K - $111K *

Lead efficient warehouse operations by supervising daily processes, enhancing safety, and guiding your team to achieve optimal performance across multiple shifts while ensuring cost-effectiveness and...

Reposted 4 days ago

  •   Less than 5 years exp.  •   Food & Beverages

$156K - $212K *

Elevate the future of bone health as a Medical Science Liaison, engaging with key opinion leaders and healthcare stakeholders to advance scientific communication and support strategic initiatives alig...

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$74K - $145K *

Lead the Claims operations team, ensuring timely processing and quality outcomes. Oversee staff performance, workflow management, and process improvements while collaborating with executive leadership...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Lead the charge in designing and optimizing scalable data pipelines and infrastructure, ensuring efficient data processing and delivery to support agency missions. Collaborate with cross-functional te...

4 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$70K - $90K *

Transform your leadership skills by guiding a dynamic team to achieve safety, quality, and performance goals while ensuring timely customer deliveries in a fast-paced environment...

4 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$110K - $130K *

Transform client security postures by delivering strategic risk assessments, developing governance frameworks, and leading cybersecurity initiatives. Collaborate with stakeholders to enhance complianc...

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$104K - $115K *

Transform your driving career with a flexible schedule that balances work and home life. Enjoy competitive pay, a generous sign-on bonus, and the opportunity to travel across multiple states while del...

4 days ago

  •   Less than 5 years exp.  •   Transportation

$72K - $90K *

Join a team that's dedicated to delivering successful projects by coordinating and managing deliverables. This role offers hands-on experience in a fast-paced environment, ensuring project profitabili...

RemoteRemote

4 days ago

  •   Less than 5 years exp.  •   Energy & Utilities

$110K - $130K *

Unlock the potential of JD Edwards data by designing robust ETL pipelines, ensuring data quality, and collaborating with cross-functional teams to support ERP implementations and reporting needs for a...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$89K - $148K *

Unlock the potential of healthcare transformation by leveraging your expertise in financial modeling and data analytics to advise state Medicaid clients and enhance public health programs across the n...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Business Services

$120K - $170K *

Lead engineering efforts by writing production code and mentoring a team. Drive modernization initiatives through Java microservices while managing performance and growth of engineers. Collaborate wit...

United StatesRemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$175K - $210K *

Unlock potential by leading Revenue Operations to drive scalable growth. Collaborate with executives to develop strategies, oversee forecasting, and enhance commercial effectiveness through data-drive...

United StatesRemote

Reposted 4 days ago

  •   11 - 15 years exp.  •   Healthcare

$120K - $130K *

Unlock potential by leading the design and optimization of secure cloud-native platforms. Collaborate across teams to enhance software delivery, implement CI/CD pipelines, and drive best practices in...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Grow your career with a consultative sales role that deepens client relationships and delivers integrated HR solutions, driving real business impact while navigating complex workforce challenges acros...

4 days ago

  •   5 - 7 years exp.  •   Business Services

$73K - $131K *

Drive analytics excellence by managing a team that transforms data into actionable insights, optimizing strategic decisions and enhancing operational efficiency across the business unit...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$107K - $180K *

Manage and deliver strategic communications for litigation and regulatory matters. Collaborate with Legal and C-suite peers, ensuring alignment between legal strategy and public voice while leading cr...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$186K - $314K *

Unlock your potential as a Senior Manager of Product Design, leading a team to refine visual identity and enhance customer experiences. Collaborate across teams to drive quality and innovation in digi...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$100K - $130K *

Elevate your career by leading impactful events that enhance visibility and engagement. Collaborate cross-functionally to develop strategic relationships and deliver high-quality experiences at confer...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Empower teams by building internal tools and automations to enhance support efficiency, diagnose issues, and collaborate with product and engineering for improved platform usability and customer exper...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $95K *

Elevate fundraising efforts by cultivating donor relationships and managing special events. Drive strategic initiatives to expand financial support for the foundation while leading a dedicated team to...

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Engineer innovative solutions as a Project Engineer, overseeing diverse projects from design to execution. Collaborate with teams to ensure quality standards and effective communication, driving conti...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Technical Services

$85K - $100K *

Optimize clinical trial execution by managing site relationships, ensuring compliance, and safeguarding patient safety. Play a key role in monitoring, training, and resolving issues to enhance study q...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$175K - $210K *

Accelerate progress at joint ventures with health systems, leading complex transactions from engagement to execution. Drive growth through partnerships, leveraging strategic relationships and operatio...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.