Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$161K - $299K *

Transform healthcare contracting by developing strategies, negotiating reimbursement agreements, and ensuring network adequacy for commercial and government providers. Lead a team to achieve operation...

United StatesRemote

4 days ago

  •   11 - 15 years exp.  •   Healthcare

$90K - $110K *

Lead IT support initiatives to ensure optimal performance of bot infrastructure. Manage setup, monitoring, and uptime of machines while growing a dedicated team within the Customer Success division. D...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$117K - $195K *

Champion innovation by leading software verification and validation efforts for critical aerospace projects. Collaborate with cross-functional teams to ensure flight software meets rigorous standards...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$95K - $135K *

Advance your career by leading product strategy for workforce solutions. Collaborate with cross-functional teams to drive innovation, ensuring products meet market needs and deliver value to diverse s...

Iowa City, IARemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$145K - $175K *

Unlock customer success by designing impactful journeys that enhance retention and revenue. As a key contributor, you'll shape service blueprints and orchestrate cross-functional teams to drive measur...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Shape the future of HR technology by leading system administration and enhancements. Collaborate across departments to optimize processes, improve data accuracy, and drive innovation in HR systems, en...

4 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$134K - $154K *

Lead the charge in designing and enhancing enterprise GRC solutions using Archer. Collaborate with stakeholders to build scalable applications, optimize workflows, and ensure compliance with business...

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$145K - $175K *

Shape the future of cybersecurity by leading Zero Trust architecture initiatives. Drive enterprise-wide strategies, develop reusable patterns, and ensure alignment with federal standards while guiding...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Information Technology

$130K - $155K *

Elevate your career by designing and training advanced machine learning models. Collaborate with experts to analyze data, create reinforcement learning environments, and communicate findings effective...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Accelerate progress at defining and driving innovative HVAC product strategies. This strategic leadership role encompasses market insight, portfolio management, and cross-functional collaboration, ens...

Reposted 4 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$76K - $186K *

Join us in driving financial planning and forecasting to enhance Revenue, Billings, and Cash Flow. Collaborate with teams to create accurate models and provide insights that shape strategic decisions...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Join a team that's pioneering biomarker research in oncology clinical studies. Drive innovative strategies, collaborate with experts, and contribute to the development of transformative therapies that...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$136K - $212K *

Join a team that's driving strategic sales enablement initiatives to empower independent agents. Lead impactful projects, manage vendor partnerships, and collaborate across functions to enhance growth...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$100K - $120K *

Lead business growth across NJ, PA, DE, MD & DC by developing new accounts, expanding existing relationships, and engaging key partners. Drive strategic initiatives and achieve sales goals in a dynami...

RemoteRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Optimize program management across the Customer Experience organization, ensuring strategic alignment and operational excellence. Lead cross-functional teams, establish governance frameworks, and driv...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Food & Beverages

$63K - $100K *

Join a team that's dedicated to enhancing patient health and quality of life. Collaborate across specialties while advancing your skills in a supportive environment focused on teamwork and continuous...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Optimize customer success by executing strategic account plans, driving product adoption, and fostering relationships to achieve risk adjustment and quality improvement goals. Collaborate with clients...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Join a team that's dedicated to enhancing healthcare applications through innovative development and support. Leverage your expertise in SYNON, COBOL, and RxCLAIM to drive impactful solutions in pharm...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$203K - $305K *

Transform regulatory intelligence by leading a global strategy that identifies and implements evolving regulatory requirements across diverse healthcare sectors, ensuring compliance and strategic alig...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Healthcare

$325K - $375K *

Lead strategic client engagement and relationship management for top-tier financial institutions. Drive revenue growth, mentor a high-performing team, and ensure delivery excellence while fostering lo...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$153K - $166K *

Empower the future of education by developing scalable web applications and cloud services. Collaborate with cross-functional teams to enhance digital assessment experiences, ensuring reliability and...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$85K - $95K *

Innovate cutting-edge solutions for public safety communications. Oversee presales projects, collaborating with sales teams to deliver tailored, high-impact solutions that meet the unique needs of fir...

RemoteRemote

4 days ago

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$80K - $95K *

Develop and nurture partnerships with school districts to drive product adoption, enhance customer success, and ensure long-term retention through strategic implementation and proactive engagement...

United StatesRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$280K - $406K *

Join us to lead transformative finance initiatives in the utilities sector, advising top executives on FERC accounting and regulatory compliance while driving operational excellence and mentoring high...

United StatesRemote

4 days ago

  •   11 - 15 years exp.  •   Information Technology

$140K - $215K *

Lead the charge in driving growth by managing a cross-functional engineering team focused on optimizing subscription platforms. Foster collaboration, enhance product strategies, and ensure technical r...

United StatesRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.