Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$224K - $431K *

Empower innovation by leading a team of engineers to enhance AI infrastructure, ensuring reliability and performance for cutting-edge research. Shape the platform's future while collaborating with div...

United StatesRemote

4 days ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$160K - $200K *

Join a team that's redefining product marketing in the insurance tech space. Lead strategic positioning, drive go-to-market initiatives, and empower teams with insights that connect product capabiliti...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$100K - $166K *

Elevate your career by managing clinical trial data processes from start to finish. Collaborate with teams to ensure quality and compliance while overseeing database development and testing for impact...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$65K - $181K *

Engage partners in innovative co-marketing strategies, driving pipeline growth through collaborative campaigns and events. Build strong relationships, advocate for partner needs, and deliver measurabl...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$95K *

Manage the strategic roadmap for TikTok Shop clients, driving growth through data-driven decisions and hands-on execution. Collaborate with teams to optimize product listings and performance while lea...

United StatesRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$137K - $195K *

Accelerate your career by driving sales of innovative bioprocessing solutions. Leverage cutting-edge technology to enhance workflows and build strong relationships with key accounts in the Mid-Atlanti...

RemoteRemote

4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$155K - $195K *

Oversee project engineering initiatives for new facility construction and technology deployment. Collaborate with cross-functional teams to ensure successful implementation and compliance, while leadi...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Transportation

$88K - $105K *

Join a team that's shaping competitive electrical bids, ensuring alignment with customer needs and organizational standards while enhancing the customer experience across our electrification division...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Empower the future of broadband by designing and overseeing FTTH networks. Lead technical initiatives, ensure compliance, and deliver scalable solutions from concept to construction while mentoring ju...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Technical Services

$80K - $115K *

Inspire data-driven decisions by enhancing our Enterprise Data Warehouse. Collaborate with diverse teams to transform transactional data into actionable KPIs, ensuring data quality and performance for...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$143K - $160K *

Unlock potential by providing global legal support for commercial transactions, managing contracts, and ensuring compliance. Collaborate with teams to drive product development and protect intellectua...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $120K *

Elevate your career by transitioning to a remote role focused on clinical analysis. Join a team dedicated to ensuring high-quality case preparation through meticulous review and organization of medica...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Pioneer seamless pharmacy integrations by managing e-prescribing workflows, ensuring compliance, and optimizing operations. Become the go-to expert for pharmacy software, enhancing patient medication...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Lead a dynamic team to enhance service delivery, drive employee development, and ensure high customer satisfaction while managing operational needs and fostering a positive organizational culture...

United StatesRemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$100K - $120K *

Transform the furniture retail landscape by driving channel expansion and managing partnerships with dealers across the U.S. Bring your expertise in sales and negotiation to unlock market growth oppor...

RemoteRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$174K - $235K *

Unlock potential by building and maintaining capacity forecasts to guide investment decisions. Collaborate across teams to ensure timely delivery and optimize resource allocation while mentoring peers...

RemoteRemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Telecommunications & Hardware

$80K - $100K *

Join a team that's driving impactful client strategies in digital marketing. As a Supervisor, you'll lead a dynamic team, manage client relationships, and oversee integrated campaigns across omnichann...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$161K - $299K *

Transform healthcare contracting by developing strategies, negotiating reimbursement agreements, and ensuring network adequacy for commercial and government providers. Lead a team to achieve operation...

United StatesRemote

4 days ago

  •   11 - 15 years exp.  •   Healthcare

$90K - $110K *

Lead IT support initiatives to ensure optimal performance of bot infrastructure. Manage setup, monitoring, and uptime of machines while growing a dedicated team within the Customer Success division. D...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$117K - $195K *

Champion innovation by leading software verification and validation efforts for critical aerospace projects. Collaborate with cross-functional teams to ensure flight software meets rigorous standards...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$95K - $135K *

Advance your career by leading product strategy for workforce solutions. Collaborate with cross-functional teams to drive innovation, ensuring products meet market needs and deliver value to diverse s...

Iowa City, IARemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$145K - $175K *

Unlock customer success by designing impactful journeys that enhance retention and revenue. As a key contributor, you'll shape service blueprints and orchestrate cross-functional teams to drive measur...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Shape the future of HR technology by leading system administration and enhancements. Collaborate across departments to optimize processes, improve data accuracy, and drive innovation in HR systems, en...

4 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$134K - $154K *

Lead the charge in designing and enhancing enterprise GRC solutions using Archer. Collaborate with stakeholders to build scalable applications, optimize workflows, and ensure compliance with business...

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$145K - $175K *

Shape the future of cybersecurity by leading Zero Trust architecture initiatives. Drive enterprise-wide strategies, develop reusable patterns, and ensure alignment with federal standards while guiding...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.