Find high-paying career opportunities across Illinois with Ladders. Browse vetted professional jobs offering salaries of $100,000 or more, from openings in Chicago to roles in cities and communities throughout the state. Whether you’re ready to take the next step in your career or explore a new industry, discover Illinois positions that match your experience and goals.
Illinois offers a broad range of professional opportunities, with a concentration of employers and roles in the Chicago area and opportunities across the rest of the state. Explore positions in fields such as finance, technology, healthcare, manufacturing, consulting, and business leadership. Available roles and compensation vary by employer, location, and experience.
Use Ladders to explore professional openings with salaries of $100,000 or more. Review job details, compare opportunities, and focus your search on the locations, industries, and responsibilities that align with your career plans. Check listings for requirements, work arrangements, and compensation details.
Start your search for a high-paying job in Illinois by browsing current listings and applying to roles that fit your qualifications. New opportunities can become available over time, so check back regularly to find the latest vetted professional jobs on Ladders.
Business Analyst - AI Response Evaluation Specialist
$80K - $95K *
Analyze and evaluate AI-generated chatbot responses to enhance accuracy and relevance. Collaborate with stakeholders to document requirements and deliver structured assessments that drive improvements...
5 days ago
Director, Higher Education Administration & Policy
$135K - $175K *
Lead the evolution of a prestigious higher education program, shaping its vision, curriculum, and faculty while fostering student success and community engagement. Collaborate across teams to ensure p...
3 days ago
Clinical Informatics Integrator
$110K - $130K *
Lead the charge in managing informatics projects from planning to delivery, ensuring timely decision-making and risk management. Collaborate with cross-functional teams to enhance health information e...
3 weeks ago
$96K *
Join a dynamic Finance team as a Financial Analyst, focusing on sales commissions and SaaS metrics. Collaborate across departments to ensure accurate financial reporting and drive insights that suppor...
1 week ago
Epic Professional Billing Analyst 2
$70K - $100K *
Join a team that's dedicated to optimizing Epic Resolute Professional Billing. Support daily operations, troubleshoot issues, and enhance workflows while collaborating with analysts and users to ensur...
2 weeks ago
Senior Full-Stack Engineer - Case Strategy
$120K - $145K *
Shape the future of healthcare by owning and optimizing AI systems. Design and deliver scalable ML solutions that transform operations, enhance decision-making, and create real-world impact across cri...
Reposted 1 week ago
Education Research Consulting Senior Associate/Associate Compliance/IRB
$100K - $145K *
Drive impactful solutions by leading project work streams, collaborating with clients, and mentoring junior staff. Leverage innovative analytics and methodologies to address unique challenges and fost...
1 week ago
$110K - $145K *
Champion innovative solutions as a Senior Business Analyst, driving requirements gathering and Agile processes to enhance custom applications for DHS. Collaborate with teams to streamline operations a...
2 weeks ago
Senior Valuations Analyst, Valuation Oversight Team
$88K - $151K *
Optimize valuation processes and governance at a leading investment firm. Drive excellence in pricing oversight, model management, and regulatory compliance while enhancing valuation capabilities and...
2 weeks ago
$108K - $130K *
Innovate cutting-edge full stack solutions by collaborating with diverse teams to address complex business challenges. Lead the design, engineering, and deployment of scalable applications using moder...
3 weeks ago
VP, Data Strategy & Governance
$180K - $220K *
Drive enterprise data strategy and governance, ensuring data quality, compliance, and innovation. Collaborate with stakeholders to foster a data-rich culture, enhance analytics capabilities, and lead...
5 days ago
$200K - $250K *
Transform investment insights through independent credit research, driving actionable recommendations and contributing to a high-performing global team managing over $70 billion in assets across diver...
Reposted 2 weeks ago
Senior Analyst, Finance (Medicare, VBC, SQL) - REMOTE
$90K - $110K *
Deliver comprehensive financial analysis and support for Medicare operations across multiple markets, driving insights and collaboration to enhance performance, forecasting, and reporting, ensuring ef...
3 weeks ago
Manager, Privacy Program Management
$108K - $130K *
Drive privacy governance by leading accountability assessments and enhancing scalable practices across functions. Collaborate globally to ensure compliance, streamline workflows, and support data subj...
3 days ago
VP, Data Strategy & Governance
$175K - $210K *
Drive the enterprise data strategy and governance, ensuring data quality, compliance, and accessibility. Lead cross-functional teams to foster a data-rich culture, enabling advanced analytics and AI r...
5 days ago
Director of Patient Navigation
$131K - $198K *
Design and implement oncology nurse navigation standards across multiple regions, ensuring seamless patient care coordination and performance improvement. Collaborate with teams to enhance patient exp...
6 days ago
$111K - $167K *
Empower your career by leading IT systems development, implementation, and maintenance. Oversee complex networks, ensure security, and drive automation, all while collaborating to enhance operational...
Reposted 2 weeks ago
Senior Auditor, Compliance Internal Audit
$100K - $120K *
Lead the charge in executing risk-based audits and enhancing AbbVie’s compliance environment while fostering stakeholder engagement and team development through a culture of collaboration and trust...
3 weeks ago
IT EPIC Principal Application Analyst
$110K - $130K *
Join a team that's driving innovation in healthcare IT by optimizing EPIC applications. You'll lead complex projects, enhance user experience, and collaborate with stakeholders to deliver robust IT so...
2 weeks ago
IT EPIC Principal Application Analyst
$110K - $130K *
Unlock your potential as a key player in optimizing EPIC applications, leading complex projects, and enhancing user experience in healthcare IT. Collaborate with stakeholders to deliver innovative sol...
2 weeks ago
$176K - $230K *
Lead the charge in transforming healthcare through data-driven solutions. As a Senior Data Scientist, you'll spearhead projects that enhance patient outcomes, leveraging your expertise to align data s...
3 weeks ago
Associate Director, Clinical Process Engineer
$150K - $180K *
Drive the evolution of clinical process engineering, establishing methodologies and governance to ensure scalable, inspection-ready processes across Clinical Development Operations while advising lead...
3 days ago
Registered Nurse (RN) - Med-Surg Neuro Stroke
$79K - $118K *
Empower patients as a vital RN on our Med-Surg telemetry unit, delivering exceptional care for stroke and neuro populations. Engage in a collaborative team environment focused on patient satisfaction...
Reposted 1 month ago
$70K - $100K *
Transform your career by joining a dynamic team that resolves complex product issues for clients in the financial technology sector. Collaborate across departments to enhance customer satisfaction and...
1 week ago
Configuration Analyst (Data Management)
$72K - $108K *
Lead key documentation for mission-critical systems, ensuring timely release and management oversight. Collaborate effectively within teams and maintain high accuracy in a fast-paced environment, enha...
Reposted 1 week ago
What types of $100,000+ jobs can I find in Illinois?
Illinois listings may include professional and leadership roles in areas such as finance, technology, healthcare, manufacturing, consulting, and business operations. Job availability and qualifications vary by employer.
Are there high-paying jobs outside Chicago?
Yes. While many opportunities are based in the Chicago area, listings may also be available in other Illinois cities and communities. Search by location to explore current openings.
How can I find Illinois jobs that pay $100,000 or more?
Browse Illinois listings on Ladders and review each job’s salary information, qualifications, location, and work arrangement. Listings feature vetted professional opportunities with salaries of $100,000 or more.
Do Illinois job listings include remote or hybrid roles?
Some listings may offer remote or hybrid work, depending on the employer and position. Check each job description for the specific work arrangement.