Explore $100K+ Jobs in Illinois

Find high-paying career opportunities across Illinois with Ladders. Browse vetted professional jobs offering salaries of $100,000 or more, from openings in Chicago to roles in cities and communities throughout the state. Whether you’re ready to take the next step in your career or explore a new industry, discover Illinois positions that match your experience and goals.

Career Opportunities Across Illinois

Illinois offers a broad range of professional opportunities, with a concentration of employers and roles in the Chicago area and opportunities across the rest of the state. Explore positions in fields such as finance, technology, healthcare, manufacturing, consulting, and business leadership. Available roles and compensation vary by employer, location, and experience.

Find a Role That Fits Your Experience

Use Ladders to explore professional openings with salaries of $100,000 or more. Review job details, compare opportunities, and focus your search on the locations, industries, and responsibilities that align with your career plans. Check listings for requirements, work arrangements, and compensation details.

Advance Your Career in Illinois

Start your search for a high-paying job in Illinois by browsing current listings and applying to roles that fit your qualifications. New opportunities can become available over time, so check back regularly to find the latest vetted professional jobs on Ladders.

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$90K - $130K *

Elevate client success by leading analytics initiatives that drive actionable insights, mentor teams, and enhance strategic decision-making through data-driven solutions and innovative marketing progr...

Yesterday

  •   5 - 7 years exp.  •   Media

$107K - $147K *

Champion the integration of business needs and technical solutions, driving product delivery through collaboration with stakeholders. Leverage your expertise to translate requirements into actionable...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$70K - $105K *

Unlock potential by performing diagnostic testing and quality control in a fast-paced laboratory environment. Collaborate with clinical staff and ensure compliance with regulatory standards while cont...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$70K - $105K *

Unlock your potential by performing critical laboratory testing and analysis. Collaborate with clinical staff, ensure quality control, and contribute to patient care in a fast-paced environment while...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Empower life sciences innovation by evaluating AI model outputs, ensuring quality and accuracy. Collaborate with cross-functional teams to enhance predictive analytics and insights, bridging clinical...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$99K - $135K *

Unlock potential by designing and implementing secure, scalable research data workflows. Collaborate with researchers and IT teams to enhance data management in complex environments, ensuring reliable...

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Drive your career with a senior role that leverages healthcare expertise to support sales processes, lead solution demonstrations, and collaborate with teams to enhance customer success and revenue gr...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$102K - $184K *

Join a dynamic team to lead complex pharmacy initiatives from design to launch, managing delivery staff and overseeing strategic programs. Collaborate across departments to ensure operational readines...

Reposted 2 days ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $130K *

Lead the charge in enhancing member care as you coach and develop clinical teams, oversee daily operations, and ensure compliance with regulatory standards while driving quality improvements and opera...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $145K *

Advance healthcare outcomes by leading project teams to design and implement tailored revenue cycle solutions, fostering collaboration and driving transformation in mission-driven organizations. Empow...

Chicago, ILRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$100K - $145K *

Accelerate progress at the intersection of healthcare and consulting by leveraging your expertise in revenue cycle solutions, driving project success, and mentoring junior team members while deliverin...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$82K - $125K *

Join our team to drive innovative analytics solutions, oversee diverse projects, and engage with clients. Leverage your expertise to transform data into actionable insights while mentoring junior anal...

Reposted today

  •   8 - 10 years exp.  •   Media

$69K - $110K *

Transform strategic decision-making by delivering quantitative market insights. Collaborate with cross-functional teams to analyze trends, forecast markets, and develop actionable strategies that driv...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$69K - $110K *

Unlock your potential as you drive strategic market insights, focusing on analysis, forecasting, and competitive intelligence to support decision-making across diverse business units in a dynamic, hyb...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$74K - $112K *

Join a team that's driving financial excellence in manufacturing. Support strategic decisions and enhance operational performance across multiple sites, leveraging analytics and financial insights to...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $140K *

Accelerate progress at the intersection of healthcare and technology by leading Epic integration projects, collaborating with teams, and ensuring seamless data workflows. Your expertise will drive the...

4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$73K - $130K *

Drive the acquisition and usability of clinical data to enhance healthcare outcomes. Collaborate with diverse teams to analyze data gaps, implement integrations, and optimize processes, ensuring timel...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$108K - $130K *

Unlock your potential by leading customer projects, ensuring seamless communication, and driving success in healthcare solutions. Collaborate with diverse teams to enhance client satisfaction and oper...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$173K - $245K *

Unlock insights through data analytics and experimentation to enhance credit risk management. Collaborate with cross-functional teams to optimize policies, monitor performance, and drive strategic gro...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$90K - $120K *

Transform the Midwest market by driving new business through strategic partnerships with brokers and employers. Leverage relationships to convert pilots into contracts while building the Aware brand a...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Unlock potential by leveraging your expertise in Epic Cogito and Clarity to enhance data analytics solutions. Collaborate with teams to design, implement, and support reporting tools that drive inform...

Yesterday

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$73K - $88K *

Champion Treasury systems performance by overseeing daily operations, supporting team enhancements, automating processes, and ensuring data quality. Collaborate with stakeholders to drive efficiency a...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$95K - $115K *

Champion healthcare solutions by managing integrations and providing expert support. Drive projects and improve processes as a Senior Interface Analyst in a dynamic and innovative environment, ensurin...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$87K - $113K *

Unlock potential by partnering with clients to design and implement data management solutions. Collaborate across teams to enhance reporting and analysis, ensuring quality and compliance while driving...

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$87K - $113K *

Support clients by designing and implementing data management solutions, ensuring quality and compliance. Collaborate across teams to analyze data, develop metrics, and provide actionable insights for...

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Illinois?question toggle

    Illinois listings may include professional and leadership roles in areas such as finance, technology, healthcare, manufacturing, consulting, and business operations. Job availability and qualifications vary by employer.

  • Are there high-paying jobs outside Chicago?question toggle

    Yes. While many opportunities are based in the Chicago area, listings may also be available in other Illinois cities and communities. Search by location to explore current openings.

  • How can I find Illinois jobs that pay $100,000 or more?question toggle

    Browse Illinois listings on Ladders and review each job’s salary information, qualifications, location, and work arrangement. Listings feature vetted professional opportunities with salaries of $100,000 or more.

  • Do Illinois job listings include remote or hybrid roles?question toggle

    Some listings may offer remote or hybrid work, depending on the employer and position. Check each job description for the specific work arrangement.