Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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$90K - $110K *

Champion patient care by evaluating and managing chronic pain conditions, collaborating with healthcare teams to create tailored treatment plans that enhance quality of life and optimize outcomes for...

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$128K - $192K *

The Workday Financials Integrations Senior Principal Consultant - Global AMS is a seasoned professional responsible for leading integration efforts and managing Workday financial services for clients...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Champion the clinical supply chain for late-stage oncology trials, ensuring seamless operations and communication between sites, suppliers, and stakeholders. Drive continuous improvement and complianc...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$160K - $176K *

Elevate medical information operations by managing inquiries, developing responses, and ensuring compliance. Collaborate with healthcare professionals to deliver high-quality communication and support...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$125K *

Engage with clients by leveraging data analysis and technical expertise to drive revenue growth. Collaborate with sales teams to ensure data accuracy and create tailored solutions, enhancing customer...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$100K - $120K *

Elevate operational efficiency by managing account priorities and delivering proactive business solutions. Collaborate with teams to ensure high-quality service and maintain strong relationships with...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$94K - $151K *

Join a team that's shaping the future of insurance products by leading strategic initiatives, ensuring compliance, and driving market analysis. Collaborate with product managers to define vision and e...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Unlock potential by designing and optimizing enterprise data solutions in a Databricks Lakehouse environment, supporting critical missions with a focus on scalability and best practices...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$139K - $220K *

Empower revenue teams by developing impactful sales enablement programs, tailored for Public Sector customers, enhancing their skills and tools to effectively deliver GitLab solutions across various g...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$90K - $110K *

Manage patient care as an Advanced-Practice Provider in a collaborative team, leveraging a large referral network and comprehensive benefits to enhance the well-being of patients in a supportive envir...

4 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Advance client relationships and team performance as a strategic leader, overseeing captive insurance operations, driving excellence, and enhancing service delivery while managing complex engagements...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$160K - $200K *

Drive enterprise sales by creating pipeline, closing complex contracts, and building strategic relationships. Collaborate with leadership to scale revenue and develop a repeatable sales motion in the...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$100K - $120K *

Drive philanthropic initiatives by managing donor relationships, developing strategies, and collaborating with leaders to enhance fundraising efforts. Engage with community stakeholders to support org...

3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$69K - $125K *

Transform regulatory insights into actionable strategies by analyzing national and state legislative activities. Collaborate with legal and business teams to ensure compliance and support effective de...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Lead compliance efforts in marketing by ensuring all materials meet legal standards. Collaborate with cross-functional teams to apply guidelines effectively while maintaining a keen attention to detai...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Advance clinical documentation accuracy by collaborating with healthcare teams to ensure comprehensive patient records, reflecting severity of illness and risk of mortality, while maintaining complian...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Join a team that's dedicated to excellence in inpatient pharmacy operations. Oversee 24-hour department functions, lead a skilled team, and drive quality care while achieving financial goals in a dyna...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$170K - $195K *

Engage in strategic account acquisition for our Legal Technologies sector, focusing on sourcing, qualifying, and closing new enterprise accounts. Drive revenue growth through complex sales cycles whil...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Legal & Accounting

$156K - $212K *

Shape the future of training by leading impactful learning solutions for obesity and related conditions. Collaborate with cross-functional teams to design and deliver engaging curricula that enhance f...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$94K - $253K *

Empower transformation in HR by leading process design and AI integration. Collaborate with clients to redefine HR functions, enhance employee experiences, and drive measurable business outcomes throu...

3 weeks ago

  •   5 - 7 years exp.  •   Business Services

$105K - $120K *

Tackle the challenges of IT modernization by providing remote and on-site support for the Air National Guard's infrastructure, ensuring seamless deployment and maintenance across numerous installation...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$162K - $195K *

Lead the launch of a novel cardiac myosin inhibitor in your territory, driving sales and building strategic relationships with healthcare providers. Collaborate with internal teams to meet patient nee...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$85K - $95K *

Unlock potential by leading business analysis to transform processes into actionable requirements for a major financial management system. Collaborate with stakeholders to enhance workflows and ensure...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Engage with patients as a Virtually Integrated Care RN, providing essential remote support and care coordination. Utilize advanced clinical skills to assess needs, develop care plans, and enhance pati...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$190K - $210K *

Unlock data-driven insights as a hybrid leader, balancing hands-on analytics with high-level client strategy. Drive impactful initiatives and foster cross-functional collaboration to deliver valuable...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.