Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.
Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.
High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.
Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.
$90K - $110K *
Champion patient care by evaluating and managing chronic pain conditions, collaborating with healthcare teams to create tailored treatment plans that enhance quality of life and optimize outcomes for...
1 week ago
$128K - $192K *
The Workday Financials Integrations Senior Principal Consultant - Global AMS is a seasoned professional responsible for leading integration efforts and managing Workday financial services for clients...
Reposted yesterday
Clinical Supply Chain Site Lead
$110K - $130K *
Champion the clinical supply chain for late-stage oncology trials, ensuring seamless operations and communication between sites, suppliers, and stakeholders. Drive continuous improvement and complianc...
6 days ago
IB Temporary - Medical Information Specialist
$160K - $176K *
Elevate medical information operations by managing inquiries, developing responses, and ensuring compliance. Collaborate with healthcare professionals to deliver high-quality communication and support...
2 weeks ago
$125K *
Engage with clients by leveraging data analysis and technical expertise to drive revenue growth. Collaborate with sales teams to ensure data accuracy and create tailored solutions, enhancing customer...
3 weeks ago
$100K - $120K *
Elevate operational efficiency by managing account priorities and delivering proactive business solutions. Collaborate with teams to ensure high-quality service and maintain strong relationships with...
3 weeks ago
Lead Product Analyst - Ancillary Products
$94K - $151K *
Join a team that's shaping the future of insurance products by leading strategic initiatives, ensuring compliance, and driving market analysis. Collaborate with product managers to define vision and e...
2 weeks ago
Computer Systems Engineer/ Architect
$110K - $130K *
Unlock potential by designing and optimizing enterprise data solutions in a Databricks Lakehouse environment, supporting critical missions with a focus on scalability and best practices...
Reposted 1 week ago
$139K - $220K *
Empower revenue teams by developing impactful sales enablement programs, tailored for Public Sector customers, enhancing their skills and tools to effectively deliver GitLab solutions across various g...
Reposted 3 weeks ago
Advanced Practice Provider (FT) | Physical Medicine & Rehabilitation | Ames | PR2026-016
$90K - $110K *
Manage patient care as an Advanced-Practice Provider in a collaborative team, leveraging a large referral network and comprehensive benefits to enhance the well-being of patients in a supportive envir...
4 weeks ago
$110K - $130K *
Advance client relationships and team performance as a strategic leader, overseeing captive insurance operations, driving excellence, and enhancing service delivery while managing complex engagements...
1 week ago
$160K - $200K *
Drive enterprise sales by creating pipeline, closing complex contracts, and building strategic relationships. Collaborate with leadership to scale revenue and develop a repeatable sales motion in the...
3 weeks ago
$100K - $120K *
Drive philanthropic initiatives by managing donor relationships, developing strategies, and collaborating with leaders to enhance fundraising efforts. Engage with community stakeholders to support org...
3 weeks ago
$69K - $125K *
Transform regulatory insights into actionable strategies by analyzing national and state legislative activities. Collaborate with legal and business teams to ensure compliance and support effective de...
1 week ago
Sr. Manager, Marketing Compliance
$110K - $130K *
Lead compliance efforts in marketing by ensuring all materials meet legal standards. Collaborate with cross-functional teams to apply guidelines effectively while maintaining a keen attention to detai...
1 week ago
RN Clinical Documentation Informaticist - Remote (see full posting for eligible states)
$80K - $95K *
Advance clinical documentation accuracy by collaborating with healthcare teams to ensure comprehensive patient records, reflecting severity of illness and risk of mortality, while maintaining complian...
1 week ago
$95K - $115K *
Join a team that's dedicated to excellence in inpatient pharmacy operations. Oversee 24-hour department functions, lead a skilled team, and drive quality care while achieving financial goals in a dyna...
2 weeks ago
$170K - $195K *
Engage in strategic account acquisition for our Legal Technologies sector, focusing on sourcing, qualifying, and closing new enterprise accounts. Drive revenue growth through complex sales cycles whil...
2 weeks ago
Senior Manager, Training & Development, Obesity & Related Conditions - U.S. Remote
$156K - $212K *
Shape the future of training by leading impactful learning solutions for obesity and related conditions. Collaborate with cross-functional teams to design and deliver engaging curricula that enhance f...
2 days ago
HR Reinvention Industry & Process Advisor Manager, Chemical & Natural Resources
$94K - $253K *
Empower transformation in HR by leading process design and AI integration. Collaborate with clients to redefine HR functions, enhance employee experiences, and drive measurable business outcomes throu...
3 weeks ago
$105K - $120K *
Tackle the challenges of IT modernization by providing remote and on-site support for the Air National Guard's infrastructure, ensuring seamless deployment and maintenance across numerous installation...
Yesterday
Cardiovascular Account Specialist - U.S. Sales, Des Moines, IA
$162K - $195K *
Lead the launch of a novel cardiac myosin inhibitor in your territory, driving sales and building strategic relationships with healthcare providers. Collaborate with internal teams to meet patient nee...
Yesterday
Business Analyst/Business Process Modeler (Remote)
$85K - $95K *
Unlock potential by leading business analysis to transform processes into actionable requirements for a major financial management system. Collaborate with stakeholders to enhance workflows and ensure...
3 weeks ago
$80K - $95K *
Engage with patients as a Virtually Integrated Care RN, providing essential remote support and care coordination. Utilize advanced clinical skills to assess needs, develop care plans, and enhance pati...
3 days ago
Senior Director, Commercial Data & Analytics
$190K - $210K *
Unlock data-driven insights as a hybrid leader, balancing hands-on analytics with high-level client strategy. Drive impactful initiatives and foster cross-functional collaboration to deliver valuable...
1 month ago
What types of $100,000+ jobs are available in Iowa?
Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.
Which Iowa cities have professional jobs paying $100,000 or more?
Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.
How can I find high-paying jobs in Iowa on Ladders?
Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.
Do Iowa job listings on Ladders include salary information?
Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.