Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

Sort By: Relevance

$150K - $180K *

Transform your career by driving strategic partnerships in healthcare. Leverage your extensive relationships within benefits consulting to influence and expand business opportunities while collaborati...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Hospitality & Recreation

$176K - $287K *

Lead the charge in advancing scientific discourse by engaging KOLs and HCPs in Hematological Malignancies. Drive strategic medical initiatives while fostering relationships to enhance research and cli...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $230K *

Engage key stakeholders in oncology by promoting innovative products, building relationships, and driving access to care. Lead strategic initiatives to exceed performance goals while embodying corpora...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$101K - $135K *

Join a team that's shaping the future of healthcare technology by designing and enhancing our build and delivery infrastructure. Collaborate with architects and developers to implement best practices...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$135K - $145K *

Drive innovative software solutions by developing robust, cloud-native systems that enhance provider data management capabilities and meet the evolving needs of clients in a dynamic, collaborative env...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $230K *

Unlock potential by driving oncology product success through strategic relationships and innovative solutions. Collaborate with healthcare professionals to enhance patient access and exceed performanc...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$140K - $190K *

Shape the future of healthcare revenue cycle performance by leading transformative initiatives, optimizing client success, and fostering innovation across multiple healthcare partnerships. Drive measu...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Join a dynamic team to drive strategic initiatives and enhance global health outcomes. Collaborate with senior leadership to synthesize complex data, manage special projects, and prepare impactful com...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $195K *

Empower quality assurance excellence by leading GMP oversight for contract manufacturing and validation projects, ensuring compliance and collaboration across technical operations to support drug deve...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $230K *

Optimize your career by driving oncology product success and building impactful relationships with healthcare professionals. Leverage your expertise to enhance patient access and deliver innovative so...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$80K - $110K *

Transform clinical data into engaging scientific content with growth opportunities. Collaborate, communicate, and adhere to guidelines in a dynamic environment, supporting varied projects across forma...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$128K - $178K *

Lead the charge in shaping the future of destination marketing through data-driven insights and innovative product strategies. Collaborate with cross-functional teams to enhance customer experiences a...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$86K - $118K *

Lead the charge in managing complex healthcare projects, ensuring timely delivery and budget adherence while coordinating cross-functional teams and mitigating risks for strategic initiatives...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Partner with us to drive strategic healthcare marketing initiatives. Lead client relationships, oversee peer-to-peer programs, and mentor team members to ensure compliance and achieve results while fo...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $230K *

Empower oncology practices by driving product adoption and building relationships with key stakeholders. Lead strategic initiatives to enhance patient access and optimize territory management while ex...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Partner with us to drive revenue growth and strategic account management across a diverse portfolio. You'll own the full sales cycle, collaborate with cross-functional teams, and build lasting relatio...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$180K - $220K *

Drive clinical excellence as a Physician Advisor, leading resource utilization and enhancing care quality through collaborative decision-making and compliance with regulations. Your expertise will sha...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $200K *

Unlock potential by leading high-performing teams in construction disputes and advisory. Drive client relationships, innovate solutions, and ensure quality execution while fostering growth and collabo...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Business Services

$150K - $230K *

Help us drive oncology product success by building relationships with key stakeholders, promoting innovative therapies, and ensuring patient access while exceeding performance goals in a dynamic bioph...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$150K - $200K *

Elevate your career by leading HCP engagement and clinical marketing initiatives. Drive strategic insights and educational content for the HSCT portfolio, fostering impactful connections and enhancing...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$94K - $293K *

Shape client membership administration by optimizing operations, implementing technology solutions, and leading project delivery. Drive growth and efficiency while building strong client relationships...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Business Services

$170K - $200K *

Lead the charge in managing complex Life Sciences programs, ensuring alignment with customer commitments. Drive delivery across teams, proactively addressing risks and building a PMO as the business s...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$70K - $100K *

Drive your career as a key Sales Executive, responsible for new client acquisition and expanding our innovative staffing services in the US market. Join a dynamic team where your expertise in building...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Staffing

$244K - $409K *

Drive the development of a global SME organization, leading regional teams to enhance technical selling and product direction. Transform ambiguity into structure while mentoring leaders and collaborat...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$180K - $215K *

Transform your career by leading regional sales efforts for a groundbreaking product. Drive performance, build a high-performing team, and engage with key healthcare providers in a fast-paced, entrepr...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.